Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Nicola Barnett"'
Autor:
Julia Schumacher, John-Paul Taylor, Calum A. Hamilton, Michael Firbank, Ruth A. Cromarty, Paul C. Donaghy, Gemma Roberts, Louise Allan, Jim Lloyd, Rory Durcan, Nicola Barnett, John T. O’Brien, Alan J. Thomas
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Objectives To investigate using quantitative EEG the (1) differences between patients with mild cognitive impairment with Lewy bodies (MCI-LB) and MCI with Alzheimer’s disease (MCI-AD) and (2) its utility as a potential biomarker for early
Externí odkaz:
https://doaj.org/article/fa6cc008671546c1a51019953d061710
Autor:
Julia Schumacher, John-Paul Taylor, Calum A. Hamilton, Michael Firbank, Ruth A. Cromarty, Paul C. Donaghy, Gemma Roberts, Louise Allan, Jim Lloyd, Rory Durcan, Nicola Barnett, John T. O'Brien, Alan J. Thomas
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102604- (2021)
Objectives: To investigate in vivo degeneration of the cholinergic system in mild cognitive impairment with Lewy bodies (MCI-LB), we studied nucleus basalis of Meynert (NBM) volumes from structural MR images and its relation to EEG slowing and cognit
Externí odkaz:
https://doaj.org/article/389e76eaff8945d7ad5edf30f2c4205b
Autor:
Paul C. Donaghy, Michael Firbank, George Petrides, Jim Lloyd, Nicola Barnett, Kirsty Olsen, Amanda Heslegrave, Henrik Zetterberg, Alan J. Thomas, John T. O'Brien
Publikováno v:
Parkinsonism & Related Disorders. 101:111-116
INTRODUCTION: Amyloid-β (Aβ) deposition is common in dementia with Lewy bodies (DLB) and has been associated with more rapid disease progression. An effective biomarker that identified the presence of significant brain Aβ in people with DLB may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb9cb883e9f19aa988ceb8e0aa9a91c
https://doi.org/10.1016/j.parkreldis.2022.07.008
https://doi.org/10.1016/j.parkreldis.2022.07.008
Autor:
Julia Schumacher, Alan J. Thomas, Calum A Hamilton, Louise Allan, Paul C. Donaghy, John-Paul Taylor, Michael J. Firbank, Gemma Roberts, Rory Durcan, Nicola Barnett, John T. O'Brien
Publikováno v:
Journal of Neurology
Funder: GE Healthcare; doi: http://dx.doi.org/10.13039/100006775
Previous resting-state fMRI studies in dementia with Lewy bodies have described changes in functional connectivity in networks related to cognition, motor function, and attention a
Previous resting-state fMRI studies in dementia with Lewy bodies have described changes in functional connectivity in networks related to cognition, motor function, and attention a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb93afc8e2e0c54e05a4dbcd7696661
http://europepmc.org/articles/PMC8563567
http://europepmc.org/articles/PMC8563567
Autor:
Nicola Barnett, Jim Lloyd, Paul C. Donaghy, George Petrides, Alan J. Thomas, John-Paul Taylor, Ian G. McKeith, Fiona E. Matthews, Calum A Hamilton, John T. O'Brien, Kirsty Olsen
Publikováno v:
The American Journal of Geriatric Psychiatry. 29:272-284
Objective We explored whether the mild cognitive impairment (MCI) stages of dementia with Lewy bodies (DLB) and Alzheimer disease (AD) differ in their cognitive profiles, and longitudinal progression. Design A prospective, longitudinal design was uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15701d643cbe1092a6ae82b52141dc1a
https://doi.org/10.1016/j.jagp.2020.07.018
https://doi.org/10.1016/j.jagp.2020.07.018
Autor:
Michael J. Firbank, Louise Allan, Paul C. Donaghy, Alan J. Thomas, Calum A Hamilton, Sally Barker, Jim Lloyd, Sean J. Colloby, John T. O'Brien, John-Paul Taylor, Joanna Ciafone, George Petrides, Gemma Roberts, Rory Durcan, Nicola Barnett, Kim Howe, Tamir Ali, Sarah Lawley
Publikováno v:
Neurology
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo provide evidence that cardiac I-123-metaiodobenzylguanidine sympathetic innervation imaging (MIBG) scintigraphy differentiates probable mild cognitive impairment with Lewy bodies (MCI-LB) from mild cognitive impairment due to Alzheimer di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83a155fc18c59513953d5f53d4e97b1
http://europepmc.org/articles/PMC8205462
http://europepmc.org/articles/PMC8205462
Autor:
Paul C. Donaghy, Kirsty Olsen, Joanna Ciafone, Sally Barker, Calum A. Hamilton, John-Paul Taylor, Michael J. Firbank, Fiona E. Matthews, Nicola Barnett, Alan J. Thomas, Ian G. McKeith, Gemma Roberts, Rory Durcan, John T. O'Brien
Publikováno v:
Neurology
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo determine whether mild cognitive impairment with Lewy bodies or mild cognitive impairment with Alzheimer disease differ in their rates of clinical progression to dementia, we undertook longitudinal observation of mild cognitive impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc924c91ec9f0f3a9dc7dfbe02a52614
http://europepmc.org/articles/PMC8205466
http://europepmc.org/articles/PMC8205466
Autor:
Rory Durcan, John T. O'Brien, Alan J. Thomas, Calum A Hamilton, Tamir Ali, Joanna Ciafone, Gemma Roberts, Michael J. Firbank, Sean J. Colloby, Kim Howe, John-Paul Taylor, Kirsty Olsen, Sally Barker, Louise Allan, Paul C. Donaghy, Sarah Lawley, Jim Lloyd, George Petrides, Nicola Barnett
Publikováno v:
The British Journal of Psychiatry. 218:276-282
BackgroundDopaminergic imaging is an established biomarker for dementia with Lewy bodies, but its diagnostic accuracy at the mild cognitive impairment (MCI) stage remains uncertain.AimsTo provide robust prospective evidence of the diagnostic accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f1b51756ae327781d9a47f38b64ebb
https://doi.org/10.1192/bjp.2020.234
https://doi.org/10.1192/bjp.2020.234
Autor:
Calum A. Hamilton, James Frith, Paul C. Donaghy, Sally A. H. Barker, Rory Durcan, Sarah Lawley, Nicola Barnett, Michael Firbank, Gemma Roberts, John‐Paul Taylor, Louise M. Allan, John O’Brien, Alison J. Yarnall, Alan J. Thomas
OBJECTIVES: Orthostatic hypotension is a common feature of normal ageing, and age-related neurodegenerative diseases, in particular the synucleinopathies including dementia with Lewy bodies. Orthostatic hypotension and other abnormal cardiovascular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe2376cf116b034c53511dc05e31ab7
Autor:
Calum A. Hamilton, James Frith, Paul C. Donaghy, Sally A. H. Barker, Rory Durcan, Sarah Lawley, Nicola Barnett, Michael Firbank, Gemma Roberts, John‐Paul Taylor, Louise M. Allan, John O’Brien, Alison J. Yarnall, Alan J. Thomas
Publikováno v:
International Journal of Geriatric Psychiatry. 37
Objectives: Autonomic symptoms are a common feature of the synucleinopathies, and may be a distinguishing feature of prodromal Lewy body disease. We aimed to assess whether the cognitive prodrome of dementia with Lewy bodies, mild cognitive impairmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c500365823fe4bda9aee5696363da12
https://doi.org/10.1002/gps.5703
https://doi.org/10.1002/gps.5703