Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Nicola Antonio, Colabufo"'
Autor:
Laura Braconi, Chiara Riganti, Astrid Parenti, Marta Cecchi, Alessio Nocentini, Gianluca Bartolucci, Marta Menicatti, Marialessandra Contino, Nicola Antonio Colabufo, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran, Elisabetta Teodori
Publikováno v:
Molecules, Vol 29, Iss 14, p 3290 (2024)
A new series of piperazine derivatives were synthesized and studied with the aim of obtaining dual inhibitors of P-glycoprotein (P-gp) and carbonic anhydrase XII (hCA XII) to synergistically overcome the P-gp-mediated multidrug resistance (MDR) in ca
Externí odkaz:
https://doaj.org/article/7f0fc90ebe6b4e25b07123ec416bb9e1
Autor:
Francesca Serena Abatematteo, Pietro Delre, Ivan Mercurio, Veronica V. Rezelj, Dritan Siliqi, Stephanie Beaucourt, Gianluca Lattanzi, Nicola Antonio Colabufo, Marcello Leopoldo, Michele Saviano, Marco Vignuzzi, Giuseppe Felice Mangiatordi, Carmen Abate
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The development of effective drugs to treat coronavirus infections remains a significant challenge for the scientific community. Recent evidence reports on the sigma-1 receptor (S1R) as a key druggable host protein in the SARS-CoV-1 and SARS
Externí odkaz:
https://doaj.org/article/165bc5a82cb64f1eb1159816b6b1c11a
Autor:
Diellza Bajrami, Syed Imdadul Hossain, Alexia Barbarossa, Maria Chiara Sportelli, Rosaria Anna Picca, Luigi Gentile, Francesco Mastrolonardo, Antonio Rosato, Alessia Carocci, Nicola Antonio Colabufo, Boris Mizaikoff, Nicola Cioffi
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25260- (2024)
This study explores how a simple argentometric titration-like approach could be evolved into a versatile, scalable, fast, and robust strategy for the production of AgCl/quaternary ammonium compounds (QACs) colloidal nanoantimicrobials (NAMs). These s
Externí odkaz:
https://doaj.org/article/b4d0818322a24ae68f7a72ba244243f8
Autor:
Stefania De Santis, Pasquale Crupi, Laura Piacente, Anna Mestice, Nicola Antonio Colabufo, Loredana Amodio, Paola Pontrelli, Loreto Gesualdo, Antonio Moschetta, Maria Lisa Clodoveo, Maria Felicia Faienza, Filomena Corbo
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Obesity represents an important public health challenge of the twenty first century reaching epidemic proportions worldwide; this is especially true for the pediatric population. In this context, bioactive compounds from foods are crucial to countera
Externí odkaz:
https://doaj.org/article/0193a5cbcf2a4ce5b05e74db68509d4a
Autor:
Laura Braconi, Gianluca Bartolucci, Marialessandra Contino, Niccolò Chiaramonte, Roberta Giampietro, Dina Manetti, Maria Grazia Perrone, Maria Novella Romanelli, Nicola Antonio Colabufo, Chiara Riganti, Silvia Dei, Elisabetta Teodori
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 974-992 (2020)
Aiming to deepen the structure–activity relationships of the two P-glycoprotein (P-gp) modulators elacridar and tariquidar, a new series of amide and ester derivatives carrying a 6,7-dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline scaffold lin
Externí odkaz:
https://doaj.org/article/80d6ac8beb384353b1f30d4afc238f16
Autor:
Carmen Abate, Mauro Niso, Francesca Serena Abatematteo, Marialessandra Contino, Nicola Antonio Colabufo, Francesco Berardi
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
These unprecedented times have forced the scientific community to gather to face the COVID-19 pandemic. Efforts in diverse directions have been made. A multi-university team has focused on the identification of the host (human) proteins interacting w
Externí odkaz:
https://doaj.org/article/b9551cfc337641e990698ea4339ee08a
Autor:
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Michele Saviano, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Publikováno v:
Journal of Medicinal Chemistry. 66:235-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c666b4e83426dc75645a7d6456be23db
https://doi.org/10.1021/acs.jmedchem.2c01084
https://doi.org/10.1021/acs.jmedchem.2c01084
Autor:
Francesca, Intranuovo, Leonardo, Brunetti, Pietro, DelRe, Giuseppe Felice, Mangiatordi, Angela, Stefanachi, Antonio, Laghezza, Mauro, Niso, Francesco, Leonetti, Fulvio, Loiodice, Alessia, Ligresti, Magdalena, Kostrzewa, Jose, Brea, Maria Isabel, Loza, Eddy, Sotelo, Michele, Saviano, Nicola Antonio, Colabufo, Chiara, Riganti, Carmen, Abate, Marialessandra, Contino
Publikováno v:
Journal of medicinal chemistry.
Cannabinoid type 2 receptor (CB2R), belonging to the endocannabinoid system, is overexpressed in pathologies characterized by inflammation, and its activation counteracts inflammatory states. Fatty acid amide hydrolase (FAAH) is an enzyme responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a17cd73abaaa431a4bd4eccf4714d7c7
https://pubmed.ncbi.nlm.nih.gov/36542836
https://pubmed.ncbi.nlm.nih.gov/36542836
Autor:
Muneyuki Sakata, Pascalle Mossel, Etsuko Imabayashi, Jun Toyohara, Nicola Antonio Colabufo, Masamichi Imai, Kenji Ishii, Gert Luurtsema, Kenji Ishibashi, Tetsuro Tago, Kei Wagatsuma
Publikováno v:
ANNALS OF NUCLEAR MEDICINE, 35(11), 1240-1252.. SPRINGER
Objective: 5-(1-(2-[18F]fluoroethoxy))-[3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-propyl]-5,6,7,8-tetrahydronaphthalen ([18F]MC225) is a selective substrate for P-glycoprotein (P-gp), possessing suitable properties for measuring overexpressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37410e392dd8958c103f4a24e13f54de
https://hdl.handle.net/11370/55ddeda6-91a7-4813-b799-3c94a4d2fba3
https://hdl.handle.net/11370/55ddeda6-91a7-4813-b799-3c94a4d2fba3
Autor:
Antonio Carrieri, Alessia Carocci, Elisabetta Casalino, Marilena Muraglia, Carlo Franchini, Filomena Corbo, Maria Maddalena Cavalluzzi, Mariagrazia Perrone, Jean-François Desaphy, Nicola Antonio Colabufo, Antonella Santoro, Gualtiero Milani, Giovanni Lentini, Concetta Altamura, Isabella Pisano
Publikováno v:
ChemMedChem. 16:3588-3599
Three analogues of To042, a tocainide-related lead compound recently reported for the treatment of myotonia, were synthesized and evaluated in vitro as skeletal muscle sodium channel blockers possibly endowed with enhanced use-dependent behavior. Pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1cec5b4690ee0ec0c35134eb266fe7
https://doi.org/10.1002/cmdc.202100496
https://doi.org/10.1002/cmdc.202100496