Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicola Andina"'
Autor:
Vanessa Alexandra Buetler, Nada Agbariah, Deborah Pia Schild, Fabian D. Liechti, Anna Wieland, Nicola Andina, Felix Hammann, Johanna A. Kremer Hovinga
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
IntroductionAn increasing number of case reports have associated vaccinations against coronavirus disease 2019 (COVID-19) with immune-mediated thrombotic thrombocytopenic purpura (iTTP), a very rare but potentially life-threatening thrombotic microan
Externí odkaz:
https://doaj.org/article/35b0b6bcd0bf4d2892465037de8d7d22
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Myeloid malignancies including myelodysplastic syndromes, myeloproliferative neoplasms and acute myeloid leukemia are heterogeneous disorders originating from mutated hematopoietic stem and progenitor cells (HSPCs). Genetically, they are very heterog
Externí odkaz:
https://doaj.org/article/db3e2ded3b6f4bdcaaa80729e8a93386
Autor:
Nicola Andina, Louise de Meuron, Annatina Sarah Schnegg-Kaufmann, Mayuresh Anant Sarangdhar, Camille Ansermet, Giuseppe Bombaci, Kiran Batta, Nino Keller, Naomi A. Porret, Anne Angelillo-Scherrer, Nicolas Bonadies, Ramanjaneyulu Allam
Publikováno v:
The Journal of Immunology. 210:580-589
Aging causes chronic low-grade inflammation known as inflamm-aging. It is a risk factor for several chronic disorders, including chronic myelomonocytic leukemia (CMML), a hematological malignancy that is most prevalent in older people. Recent studies
Publikováno v:
Sarangdhar, Mayuresh Anant; Andina, Nicola; Allam, Ramanjaneyulu (2023). Human molecular genetics sheds light on the physiological significance of ribonuclease inhibitor (RNH1). (In Press). European journal of human genetics Springer Nature 10.1038/s41431-023-01362-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffba7ff559a8029898ea0d0b26fa4f8
https://boris.unibe.ch/181924/1/s41431-023-01362-4.pdf
https://boris.unibe.ch/181924/1/s41431-023-01362-4.pdf
Autor:
Nicola Andina, Louise de Meuron, Annatina Sarah Schnegg-Kaufmann, Camille Ansermet, Giuseppe Bomaci, Nino Keller, Naomi Porret, Anne Angelillo-Scherrer, Nicolas Bonadies, Ramanjaneyulu Allam
Aging causes chronic low-grade inflammation known as inflamm-aging. It is a risk factor for chronic myelomonocytic leukemia (CMML), a hematological malignancy that is most prevalent in older people. Recent studies suggest a critical role for the NLRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad2fff829ae5fd3ebf637751059323c2
https://doi.org/10.1101/2022.01.27.477992
https://doi.org/10.1101/2022.01.27.477992
Autor:
Nicolas Bonadies, Joerg C. Schefold, Aubry Tardivel, Eric Chi-Wang Yu, Vedat Burak Ozan, Thibaud Spinetti, Esther Youd, Amiq Gazdhar, Kendle M. Maslowski, Ramanjaneyulu Allam, Pascal Schneider, Cédric Hirzel, Matthew Pugh, Mayuresh Anant Sarangdhar, Anne Angelillo-Scherrer, Giuseppe Bombaci, Graham S. Taylor, Yara Banz, Gillian M Mackie, Nicola Andina
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1 mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2b115e460eb414c2a9e1f238495ed2
https://doi.org/10.1101/2021.04.12.438219
https://doi.org/10.1101/2021.04.12.438219
Autor:
Roland von Känel, Cesar A. Hincapié, Peter E. Keller, Christoph Niederhauser, Bernhard Lämmle, Bruno R. da Costa, Nicola Andina, Peter Jüni, Stefano Fontana, Tobias E. Erlanger
Publikováno v:
Keller, Peter; von Känel, Roland; Hincapié, Cesar A; da Costa, Bruno R; Jüni, Peter; Erlanger, Tobias E; Andina, Nicola; Niederhauser, Christoph; Lämmle, Bernhard; Fontana, Stefano (2020). The effects of intravenous iron supplementation on fatigue and general health in non-anemic blood donors with iron deficiency: a randomized placebo-controlled superiority trial. Scientific reports, 10(1), p. 14219. Springer Nature 10.1038/s41598-020-71048-0
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
We investigated whether intravenous iron supplementation improves fatigue and general health in non-anemic repeat adult blood donors with iron deficiency (ferritin ≤ 50 µg/L). Of 1,487 potentially eligible participants, 203 were randomly assigned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a316a2e018fdac0cf322e18065325ad5
Autor:
Stefan Kuchen, Thomas Daikeler, Ramanjaneyulu Allam, Nicolas Bonadies, B. Kipfer, Mahmoud Hallal, Nicola Andina
Publikováno v:
Seminars in Hematology. 55:242-247
Myelodysplastic syndromes (MDS) and associated diseases, like chronic myelomonocytic leukemias (CMML), are heterogeneous, clonal disorders affecting the hematopoietic stem cells. They are characterized by dysplasia and a propensity to evolve toward a
Autor:
Sarah Dimeloe, Max Gassmann, Vladan P. Čokić, Florian Geier, Julien Delezie, Julia Magdalena Majewska, Teresa Cassel, Jonel Trebicka, Thomas Radimerski, Deniz Gezer, Christoph Handschin, Nils Hansen, Radek C. Skoda, Shivam Rai, Danijela Lekovic, Dominik Wolf, Ronny Nienhold, Hui Hao-Shen, Nicolaus Kröger, Serena Di Palma, Steffen Koschmieder, Serena Galli, Andrew N. Lane, Stefan Dirnhofer, Christian Beisel, Julian Hilfiker, Teresa W.-M. Fan, Christoph Hess, Nicola Andina, Tata Nageswara Rao
Publikováno v:
Blood, 134 (21)
Blood
Rao, T N, Hansen, N, Hilfiker, J, Rai, S, Majewska, J M, Leković, D, Gezer, D, Andina, N, Galli, S, Cassel, T, Geier, F, Delezie, J, Nienhold, R, Hao-Shen, H, Beisel, C, Di Palma, S, Dimeloe, S, Trebicka, J, Wolf, D, Gassmann, M, Fan, T W M, Lane, A N, Handschin, C, Dirnhofer, S, Kröger, N, Hess, C, Radimerski, T, Koschmieder, S, Čokić, V P & Skoda, R C 2019, ' JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms ', Blood, vol. 134, no. 21, pp. 1832-1846 . https://doi.org/10.1182/blood.2019000162
Blood
Rao, T N, Hansen, N, Hilfiker, J, Rai, S, Majewska, J M, Leković, D, Gezer, D, Andina, N, Galli, S, Cassel, T, Geier, F, Delezie, J, Nienhold, R, Hao-Shen, H, Beisel, C, Di Palma, S, Dimeloe, S, Trebicka, J, Wolf, D, Gassmann, M, Fan, T W M, Lane, A N, Handschin, C, Dirnhofer, S, Kröger, N, Hess, C, Radimerski, T, Koschmieder, S, Čokić, V P & Skoda, R C 2019, ' JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms ', Blood, vol. 134, no. 21, pp. 1832-1846 . https://doi.org/10.1182/blood.2019000162
Increased energy requirement and metabolic reprogramming are hallmarks of cancer cells. We show that metabolic alterations in hematopoietic cells are fundamental to the pathogenesis of mutant JAK2-driven myeloproliferative neoplasms (MPNs). We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4047e0fcbabe5128de1eaedb1f014e6c
https://hdl.handle.net/20.500.11850/382118
https://hdl.handle.net/20.500.11850/382118
Autor:
Ramanjaneyulu Allam, Aubry Tardivel, Mayuresh Anant Sarangdhar, Giuseppe Bombaci, Nicola Andina, Mahmoud Hallal, Irene Keller
Publikováno v:
Blood. 134:273-273
Hematopoietic stem cells (HSC) in higher vertebrate species, especially in mammals, maintain hematopoiesis throughout adult life and require critical cell cycle regulation for their self-renewal and cell fate decisions. Although cell cycle pathways a