Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Nicola La Monica"'
Autor:
Gloria C. Koo, Daniela Peruzzi, Luigi Aurisicchio, Nicola La Monica, Gennaro Ciliberto, Wei Zen Wei
Publikováno v:
Human Gene Therapy. 25:121-131
Several cancer vaccine efforts have been directed to simultaneously cotarget multiple tumor antigens, with the intent to achieve broader immune responses and more effective control of cancer growth. Genetic cancer vaccines based on in vivo muscle ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ca18639bb2a9961ffec62e02913a48
https://doi.org/10.1089/hum.2013.103
https://doi.org/10.1089/hum.2013.103
Autor:
Nicola La Monica, Lakshmi Bhagat, Dong Yu, Jimmy X. Tang, Sudhir Agrawal, Fu-Gang Zhu, Ekambar R. Kandimalla, Weiwen Jiang
Publikováno v:
Journal of Investigative Dermatology. 133:1777-1784
Psoriasis is a chronic inflammatory skin disease that involves the induction of T-helper 1 (Th1) and T-helper 17 (Th17) cell responses and the aberrant expression of proinflammatory cytokines, including IL-1β. Copious evidence suggests that abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d538cca18947ae36126a9beae7cff02
https://doi.org/10.1038/jid.2013.57
https://doi.org/10.1038/jid.2013.57
Autor:
Fu-Gang Zhu, Sudhir Agrawal, Ekambar R. Kandimalla, Jimmy X. Tang, Lakshmi Bhagat, Dong Yu, Daqing Wang, Nicola La Monica, Weiwen Jiang
Publikováno v:
Autoimmunity. 46:419-428
Systemic Lupus Erythematosus is an autoimmune disease characterized by production of autoantibodies against nucleic acid-associated antigens. Endogenous DNA and RNA associated with these antigens stimulate inflammatory responses through Toll-like rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee54cc2b566970baa95b3966741992f
https://doi.org/10.3109/08916934.2013.798651
https://doi.org/10.3109/08916934.2013.798651
Autor:
Francois H.T. Duong, Nicola La Monica, Tanja Blumer, Ekambar R. Kandimalla, Markus H. Heim, Zuzanna Makowska
Publikováno v:
Journal of hepatology
Background & Aims The toll-like receptor 9 (TLR9) agonist IMO-2125 is currently evaluated in clinical trials for chronic hepatitis C therapy. The aim of this study was to investigate the in vivo mode of action of a closely related compound, referred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e413bb5d68bc8fb0554330baf769b3eb
https://doi.org/10.1016/j.jhep.2012.11.038
https://doi.org/10.1016/j.jhep.2012.11.038
Autor:
Timothy J. Sullivan, Nicola La Monica, Ekambar R. Kandimalla, Sudhir Agrawal, Daqing Wang, Lakshmi Bhagat, Dong Yu
Publikováno v:
Nucleic Acids Research
Oligonucleotides containing an immune-stimulatory motif and an immune-regulatory motif act as antagonists of Toll-like receptor (TLR)7 and TLR9. In the present study, we designed and synthesized oligonucleotide-based antagonists of TLR7, 8 and 9 cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54eaf3108537804ed6a85646e629b0e
https://doi.org/10.1093/nar/gkt078
https://doi.org/10.1093/nar/gkt078
Autor:
Daniela Peruzzi, Gennaro Ciliberto, Irene Pak, Ansuman Bagchi, Danilo R. Casimiro, Luigi Aurisicchio, Nicola La Monica, Arthur Fridman, Adam C. Finnefrock
Publikováno v:
Oncoimmunology
Functional T-cell epitope discovery is a key process for the development of novel immunotherapies, particularly for cancer immunology. In silico epitope prediction is a common strategy to try to achieve this objective. However, this approach suffers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6f0926ba223e02ef4383efa9a54e72
https://doi.org/10.4161/onci.21355
https://doi.org/10.4161/onci.21355
Publikováno v:
Vaccine. 28:1201-1208
Pet dogs represent a valuable pre-clinical model to assess the efficacy of oncology drugs. Additionally, canine cancers occur with an incidence similar to that of humans and share many features with human malignancies including histological appearanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e295a82b2c6737ebff9c3b293e5eb77c
https://doi.org/10.1016/j.vaccine.2009.11.031
https://doi.org/10.1016/j.vaccine.2009.11.031
Autor:
Angelos D. Gritzapis, Sonia A. Perez, Michael Papamichail, Arthur Fridman, Constantin N. Baxevanis, Nicola La Monica, Luigi Aurisicchio
Publikováno v:
Vaccine. 28:162-170
The HER-2/neu oncoprotein is a promising cancer vaccine target. We describe herein a novel HLA-A2.1-restricted epitope, encompassing amino acids 657-665 (AVVGILLVV), which is naturally presented by human breast and ovarian cell lines. HER-2/neu(657-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e599514cb2424f9af8d4ddf374e4ead
https://doi.org/10.1016/j.vaccine.2009.09.104
https://doi.org/10.1016/j.vaccine.2009.09.104
Autor:
Saverio Giampaoli, Nicola La Monica, Daniela Peruzzi, Francesco Calvaruso, Gennaro Ciliberto, Giuseppe Mesiti, Elisa Scarselli, Ekambar R. Kandimalla, Sudhir Agrawal, Carmela Mennuni, Sridhar Dharmapuri, Gaetano Barbato, Luigi Aurisicchio
Publikováno v:
Molecular Therapy. 17:1804-1813
The human telomerase reverse transcriptase (hTERT) is an attractive target for human cancer vaccination because its expression is reactivated in most human tumors. We have evaluated the ability of DNA electroporation (DNA-EP) and adenovirus serotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663ad7a4890996228f4105104f764d3e
https://doi.org/10.1038/mt.2009.165
https://doi.org/10.1038/mt.2009.165
Autor:
Antonella Conforti, Gennaro Ciliberto, Luigi Aurisicchio, Antonella Biondo, Nicola La Monica, Daniela Peruzzi, Patrizia Giannetti
Publikováno v:
ResearcherID
Human leukocyte antigen (HLA)-A2.1 transgenic mice (HHD) represent a valuable model to study and predict the immunogenicity of vaccines against pathogens. However, HHD mice are unsuitable for in vivo studies of cancer vaccines against human tumor-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8def2601424ccb108ef6076e868aeb
https://doi.org/10.1097/cji.0b013e3181aee1b6
https://doi.org/10.1097/cji.0b013e3181aee1b6