Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicola, Zilio"'
Autor:
Kook Son, Vakil Takhaveev, Visesato Mor, Hobin Yu, Emma Dillier, Nicola Zilio, Nikolai J. L. Püllen, Dmitri Ivanov, Helle D. Ulrich, Shana J. Sturla, Orlando D. Schärer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Most genotoxic anticancer agents fail in tumors with intact DNA repair. Therefore, trabectedin, anagent more toxic to cells with active DNA repair, specifically transcription-coupled nucleotide excision repair (TC-NER), provides therapeutic
Externí odkaz:
https://doaj.org/article/1a45c02a032c494596a84c053a37fd46
Autor:
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
Publikováno v:
eLife, Vol 11 (2022)
The human SMC5/6 complex is a conserved guardian of genome stability and an emerging component of antiviral responses. These disparate functions likely require distinct mechanisms of SMC5/6 regulation. In yeast, Smc5/6 is regulated by its Nse5/6 subu
Externí odkaz:
https://doaj.org/article/ce310930ec9f4a289ae733b44d09acec
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100076- (2020)
Summary: GLOE-Seq is a next-generation sequencing method for the genome-wide mapping of 3′-OH termini, either resulting from single- or double-strand breaks or introduced by enzymatic conversion of lesions or modified nucleotides. This protocol pro
Externí odkaz:
https://doaj.org/article/271be5ee97a1498598352e58f80f9bb0
Autor:
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36cf4ac37486df5deea1fc767a563a32
https://doi.org/10.7554/elife.79676.sa2
https://doi.org/10.7554/elife.79676.sa2
Autor:
Nicola Zilio, Helle D. Ulrich
Publikováno v:
The FEBS journalReferences. 288(13)
Mapping the genome-wide distribution of DNA lesions is key to understanding damage signalling and DNA repair in the context of genome and chromatin structure. Analytical tools based on high-throughput next-generation sequencing have revolutionized ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5b5216f4cc5bf14cf9b806c46e61f9
https://pubmed.ncbi.nlm.nih.gov/32965079
https://pubmed.ncbi.nlm.nih.gov/32965079
Autor:
María Méndez-Lago, Axel J. Schäfer, Nicola Zilio, Giuseppe Petrosino, Annie M. Sriramachandran, Liliana S. Batista-Nascimento, Helle D. Ulrich
Publikováno v:
Molecular Cell
Summary DNA single-strand breaks (SSBs) are among the most common lesions in the genome, arising spontaneously and as intermediates of many DNA transactions. Nevertheless, in contrast to double-strand breaks (DSBs), their distribution in the genome h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c72c98b244c257d747be428d9803556
https://doi.org/10.1016/j.molcel.2020.03.027
https://doi.org/10.1016/j.molcel.2020.03.027
Publikováno v:
Molecular Cell. 77:3-16.e4
Tracing DNA repair factors by fluorescence microscopy provides valuable information about how DNA damage processing is orchestrated within cells. Most repair pathways involve single-stranded DNA (ssDNA), making replication protein A (RPA) a hallmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cbc8e18ae575cb69bd1be297091ea8
https://doi.org/10.1016/j.molcel.2019.09.015
https://doi.org/10.1016/j.molcel.2019.09.015
Autor:
Nicola Zilio
Publikováno v:
Ricerche giuridiche.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a95d375279c390d695cbfd88b5283d4f
https://doi.org/10.30687/rg/2281-6100/2018/02/010
https://doi.org/10.30687/rg/2281-6100/2018/02/010
Publikováno v:
Advances in experimental medicine and biology. 963
Like in most other areas of cellular metabolism, the functions of the ubiquitin-like modifier SUMO in the maintenance of genome stability are manifold and varied. Perturbations of global sumoylation causes a wide spectrum of phenotypes associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97c95a71308b53cdfb8c3f3aad3f2804
https://pubmed.ncbi.nlm.nih.gov/28197906
https://pubmed.ncbi.nlm.nih.gov/28197906
Publikováno v:
SUMO Regulation of Cellular Processes ISBN: 9783319500430
Like in most other areas of cellular metabolism, the functions of the ubiquitin-like modifier SUMO in the maintenance of genome stability are manifold and varied. Perturbations of global sumoylation causes a wide spectrum of phenotypes associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52fe49b6ec0b8606d217f4dcbdf04d5c
https://doi.org/10.1007/978-3-319-50044-7_4
https://doi.org/10.1007/978-3-319-50044-7_4