Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicola, Vajente"'
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The endoplasmic reticulum (ER) is a highly dynamic network whose shape is thought to be actively regulated by membrane resident proteins. Mutation of several such morphology regulators cause the neurological disorder Hereditary Sp astic Paraplegia (H
Externí odkaz:
https://doaj.org/article/b8482dc739fb4e6ea19e6786f990583e
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change their morphology and position within the cells in response to physiological stimuli and these n
Externí odkaz:
https://doaj.org/article/24159bd9fed94ceb9fe0d1c16a9d08c9
Autor:
Paola Pizzo, Emy Basso, Riccardo Filadi, Elisa Greotti, Alessandro Leparulo, Diana Pendin, Nelly Redolfi, Michela Rossini, Nicola Vajente, Tullio Pozzan, Cristina Fasolato
Publikováno v:
Cells, Vol 9, Iss 10, p 2166 (2020)
Presenilin-2 (PS2) is one of the three proteins that are dominantly mutated in familial Alzheimer’s disease (FAD). It forms the catalytic core of the γ-secretase complex—a function shared with its homolog presenilin-1 (PS1)—the enzyme ultimate
Externí odkaz:
https://doaj.org/article/77b7dcffd7784e8b81cd1a266393c925
Publikováno v:
International Journal of Molecular Sciences
Calcium (Ca2+) exerts a pivotal role in controlling both physiological and detrimental cellular processes. This versatility is due to the existence of a cell-specific molecular Ca2+ toolkit and its fine subcellular compartmentalization. Study of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02caa12970bc489ad2ce67b7c1672cf8
https://pubmed.ncbi.nlm.nih.gov/34576104
https://pubmed.ncbi.nlm.nih.gov/34576104
Autor:
Nelly Redolfi, Paola Pizzo, Diana Pendin, Elisa Greotti, Alessandro Leparulo, Cristina Fasolato, Tullio Pozzan, Elena Scremin, Riccardo Filadi, Chiara Gomiero, Emy Basso, Luisa Galla, Nicola Vajente
Publikováno v:
Aging Clinical and Experimental Research. 33:1705-1708
Alzheimer's disease (AD) is the most frequent cause of dementia in the elderly. Few cases are familial (FAD), due to autosomal dominant mutations in presenilin-1 (PS1), presenilin-2 (PS2) or amyloid precursor protein (APP). The three proteins are inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f075f9484575d3a5d2f03df1e1cb4ca
https://doi.org/10.1007/s40520-019-01341-0
https://doi.org/10.1007/s40520-019-01341-0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2275
Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::777c4048658224d13785068a0071594c
https://pubmed.ncbi.nlm.nih.gov/34118039
https://pubmed.ncbi.nlm.nih.gov/34118039
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612613
Ca2+ handling by mitochondria is implicated in energy production, shaping of cytosolic Ca2+ rises, and determination of cell fate. It is therefore of crucial interest for researchers to directly measure mitochondrial Ca2+ concentration [Ca2+] in livi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e18448ab8cd9b393c8dac832f42b36
http://hdl.handle.net/11577/3415455
http://hdl.handle.net/11577/3415455
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030124564
Drosophila melanogaster, colloquially known as the fruit fly, is one of the most commonly used model organisms in scientific research. Although the final architecture of a fly and a human differs greatly, most of the fundamental biological mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd54b73006981c4514aa4cfbdcc5b75
http://hdl.handle.net/11577/3322022
http://hdl.handle.net/11577/3322022
Autor:
Elisa Greotti, Alessandro Leparulo, Nelly Redolfi, Paola Pizzo, Cristina Fasolato, Michela Rossini, Tullio Pozzan, Riccardo Filadi, Nicola Vajente, Emy Basso, Diana Pendin
Publikováno v:
Cells, Vol 9, Iss 2166, p 2166 (2020)
Cells
Cells
Presenilin-2 (PS2) is one of the three proteins that are dominantly mutated in familial Alzheimer’s disease (FAD). It forms the catalytic core of the γ-secretase complex—a function shared with its homolog presenilin-1 (PS1)—the enzyme ultimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804b4208493c6f66a5fca96ae12bfbae
http://hdl.handle.net/11577/3358594
http://hdl.handle.net/11577/3358594
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change their morphology and position within the cells in response to physiological stimuli and these n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ced881e4ddf728f164d2cf77bdab952
https://doi.org/10.3389/fphys.2019.01544
https://doi.org/10.3389/fphys.2019.01544