Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Nicola, Specchio"'
Autor:
Simona Cappelletti, Cinzia Correale, Mattia Mercier, Giusy Carfi Pavia, Chiara Falamesca, Alessandro De Benedictis, Carlo Efisio Marras, Chiara Quintavalle, Concetta Luisi, Chiara Pepi, Daniela Chiarello, Federico Vigevano, Luca De Palma, Nicola Specchio
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1901-1909 (2024)
Abstract Objective The aim of this study is to describe the pre‐ and post‐operative developmental and intellectual functions in a cohort of patients who underwent surgery for drug‐resistant epilepsy (DRE) before the age of 5 years. Method We re
Externí odkaz:
https://doaj.org/article/2e7e6ab25e70459aaf2b1a70772c8faf
Autor:
Elaine C. Wirrell, Lieven Lagae, Ingrid E. Scheffer, J. Helen Cross, Nicola Specchio, Adam Strzelczyk
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1643-1657 (2024)
Abstract Fenfluramine (FFA), an antiseizure medication (ASM) with serotonergic and sigma‐1 receptor activity, is used to manage patients with developmental and epileptic encephalopathies (DEEs). It is approved in the US for treating seizures associ
Externí odkaz:
https://doaj.org/article/3dc1b09b0bfc46e7857e957e7df05a9b
Autor:
Antonella Riva, Antonietta Coppola, Francesca Bisulli, Alberto Verrotti, Irene Bagnasco, Maurizio Elia, Francesca Darra, Simona Lattanzi, Stefano Meletti, Angela La Neve, Giancarlo Di Gennaro, Isabella Brambilla, Katia Santoro, Tommaso Prisco, Francesca Macari, Antonio Gambardella, Carlo diBonaventura, Simona Balestrini, Carla Marini, Dario Pruna, Giuseppe Capovilla, Nicola Specchio, Giuseppe Gobbi, Pasquale Striano, the iRARE Study Group
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1857-1867 (2024)
Abstract Objective Rare and complex epilepsies encompass a diverse range of disorders characterized by seizures. We aimed to establish a consensus on key issues related to these conditions through collaboration among experienced neurologists, neurope
Externí odkaz:
https://doaj.org/article/aee12165e9f44506874795f612aec97d
Autor:
Nicola Pietrafusa, Luca De Palma, Michelina Armando, Tiziana Corsetti, Federico Vigevano, Nicola Specchio
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1997-1999 (2024)
Externí odkaz:
https://doaj.org/article/04ffc2ed56eb47b7a1ddfdab75db255a
Autor:
Michele Rizzi, Alessandro Consales, Irene Tramacere, Alessandro De Benedictis, Antonella Bua, Nicola Specchio, Luca De Palma, Erica Cognolato, Lino Nobili, Domenico Tortora, Carmen Barba, Marianna Pommella, Flavio Giordano, Chiara Pastori, Marcello Marchetti, Rita Garbelli, Mino Zucchelli, Matteo Martinoni, Lorenzo Ferri, Matia Martucci, Gianpiero Tamburrini, Federico Bianchi, Claudia Passamonti, Giancarlo Di Gennaro, Flavio Villani, Laura Tassi, Carlo Marras
Publikováno v:
Epilepsia Open, Vol 9, Iss 4, Pp 1493-1501 (2024)
Abstract Objective To investigate the Italian experience on the surgical and radiosurgical treatment of drug‐resistant epilepsy due to hypothalamic hamartoma (HH) in the period 2011–2021 in six Italian epilepsy surgery centers, and to compare saf
Externí odkaz:
https://doaj.org/article/e902478300b644a0b6a995940e025d77
Autor:
Carmen Barba, Veronica Pelliccia, Laura Grisotto, Luca De Palma, Giulia Nobile, Francesca Gozzo, Martina Revay, Giusy Carfi‐Pavia, Massimo Cossu, Flavio Giordano, Alessandro Consales, Alessandro De Benedictis, Elena Cavallini, Cristina Mion, Claudia Accolla, Nicola Specchio, Lino Nobili, Renzo Guerrini, Laura Tassi
Publikováno v:
Epilepsia Open, Vol 9, Iss 4, Pp 1382-1392 (2024)
Abstract Objective To assess seizure and developmental outcomes, their predictors, and complications in 160 children who, between 1998 and 2022, underwent surgery for lesional epilepsy with curative intent before the age of 3 years. To compare trends
Externí odkaz:
https://doaj.org/article/228dbd066402451ab05478a7a21eaa04
Autor:
Maria T. Papadopoulou, Lorenzo Muccioli, Francesca Bisulli, Kerstin Alexandra Klotz, Carmen Fons, Marina Trivisano, Teia Kabulashvili, Nicola Specchio, Gaetan Lesca, Alexis Arzimanoglou
Publikováno v:
Epilepsia Open, Vol 9, Iss 3, Pp 996-1006 (2024)
Abstract Objective The increasingly rapid pace of advancement in genetic testing may lead to inequalities in technical and human resources with a negative impact on optimal epilepsy clinical practice. In this view, the European Reference Network (ERN
Externí odkaz:
https://doaj.org/article/a4b6b2fc2f654ee089043121e6151671
Autor:
Sam Amin, Rikke S. Møller, Angel Aledo‐Serrano, Alexis Arzimanoglou, Patrick Bager, Sergiusz Jóźwiak, Gerhard Josef Kluger, Sandra López‐Cabeza, Rima Nabbout, Carol‐Anne Partridge, Susanne Schubert‐Bast, Nicola Specchio, Reetta Kälviäinen
Publikováno v:
Epilepsia Open, Vol 9, Iss 3, Pp 832-849 (2024)
Abstract Cyclin‐dependent kinase‐like 5 (CDKL5) deficiency disorder (CDD) is a developmental and epileptic encephalopathy caused by variants in the CDKL5 gene. The disorder is characterized by intractable early‐onset seizures, severe neurodevel
Externí odkaz:
https://doaj.org/article/e1b18ace19a548f987304aa2382d5955
Autor:
Mattia Mercier, Chiara Pepi, Giusy Carfi-Pavia, Alessandro De Benedictis, Maria Camilla Rossi Espagnet, Greta Pirani, Federico Vigevano, Carlo Efisio Marras, Nicola Specchio, Luca De Palma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Epilepsy surgery is effective for patients with medication-resistant seizures, however 20–40% of them are not seizure free after surgery. Aim of this study is to evaluate the role of linear and non-linear EEG features to predict post-surgi
Externí odkaz:
https://doaj.org/article/ed4209e5482f4b9eaaf8a748a6258e1f
Autor:
Nazanin Azarinejad Mohammadi, Philip Kiær Ahring, Vivian Wan Yu Liao, Han Chow Chua, Sebastián Ortiz de la Rosa, Katrine Marie Johannesen, Yael Michaeli-Yossef, Aline Vincent-Devulder, Catherine Meridda, Ange-Line Bruel, Alessandra Rossi, Chirag Patel, Joerg Klepper, Paolo Bonanni, Sara Minghetti, Marina Trivisano, Nicola Specchio, David Amor, Stéphane Auvin, Sarah Baer, Pierre Meyer, Mathieu Milh, Vincenzo Salpietro, Reza Maroofian, Johannes R. Lemke, Sarah Weckhuysen, Palle Christophersen, Guido Rubboli, Mary Chebib, Anders A. Jensen, Nathan L. Absalom, Rikke Steensbjerre Møller
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105236- (2024)
Summary: Background: Variants in GABRB2, encoding the β2 subunit of the γ-aminobutyric acid type A (GABAA) receptor, can result in a diverse range of conditions, ranging from febrile seizures to severe developmental and epileptic encephalopathies.
Externí odkaz:
https://doaj.org/article/1f75a6fe61cf4a01b76139af961cda76