Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nicolò Salvarani"'
Autor:
Margherita Burattini, Francesco Paolo Lo Muzio, Mirko Hu, Flavia Bonalumi, Stefano Rossi, Christina Pagiatakis, Nicolò Salvarani, Lorenzo Fassina, Giovanni Battista Luciani, Michele Miragoli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The heart coordinates its functional parameters for optimal beat-to-beat mechanical activity. Reliable detection and quantification of these parameters still represent a hot topic in cardiovascular research. Nowadays, computer vision allows
Externí odkaz:
https://doaj.org/article/8bab4f0e44bc4a6a8a7923f4c0bfa983
Autor:
Paola Lagonegro, Stefano Rossi, Nicolò Salvarani, Francesco Paolo Lo Muzio, Giacomo Rozzi, Jessica Modica, Franca Bigi, Martina Quaretti, Giancarlo Salviati, Silvana Pinelli, Rossella Alinovi, Daniele Catalucci, Francesca D’Autilia, Ferdinando Gazza, Gianluigi Condorelli, Francesca Rossi, Michele Miragoli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Silicon-based materials have the ability to support bioelectrical activity. Here the authors show how injectable silicon carbide nanowires reduce arrhythmias and rapidly restore conduction in a myocardial infarction model.
Externí odkaz:
https://doaj.org/article/ab601cecf18e4dd68348d8cbc2849cfe
Autor:
Nicolò Salvarani, Giovanni Peretto, Crasto Silvia, Andrea Villatore, Cecilia Thairi, Anna Santoni, Camilla Galli, Paola Carrera, Simone Sala, Sara Benedetti, Elisa Di Pasquale, Chiara Di Resta
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9548 (2023)
Brugada syndrome (BrS) is an inherited autosomal dominant cardiac channelopathy. Pathogenic rare mutations in the SCN5A gene, encoding the alpha-subunit of the voltage-dependent cardiac Na+ channel protein (Nav1.5), are identified in 20% of BrS patie
Externí odkaz:
https://doaj.org/article/3110b987a88146039a487026877f7c4e
Autor:
Nicolò Salvarani, Silvia Crasto, Michele Miragoli, Alessandro Bertero, Marianna Paulis, Paolo Kunderfranco, Simone Serio, Alberto Forni, Carla Lucarelli, Matteo Dal Ferro, Veronica Larcher, Gianfranco Sinagra, Paolo Vezzoni, Charles E. Murry, Giuseppe Faggian, Gianluigi Condorelli, Elisa Di Pasquale
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Mutation of LMNA, encoding Lamin A/C nuclear proteins, cause dilated cardiomyopathy and conduction disorders. Here, the authors show that patient-specific iPSC-derived CMs carrying the K219T LMNA mutation have downregulated Nav1.5 channels due to dyn
Externí odkaz:
https://doaj.org/article/975fc60819e84ad6adb18ec63c887d5c
Autor:
Vittoria Di Mauro, Paola Ceriotti, Francesco Lodola, Nicolò Salvarani, Jessica Modica, Marie-Louise Bang, Andrea Mazzanti, Carlo Napolitano, Silvia G. Priori, Daniele Catalucci
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Brugada syndrome (BrS) is an inherited arrhythmogenic disease that may lead to sudden cardiac death in young adults with structurally normal hearts. No pharmacological therapy is available for BrS patients. This situation highlights the urgent need t
Externí odkaz:
https://doaj.org/article/185089ae836f4f82a40fa10a9c2cfed3
Autor:
Floriana Maria Farina, Gianluigi Condorelli, Manuela Quintavalle, Pierluigi Carullo, Leonardo Elia, Simone Serio, Nicolò Salvarani, Montserrat Climent, Stefania Maria Zani, Ignacio Fernando Hall, Efrem Civilini
Publikováno v:
Circulation research. 126(12)
Rationale: MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene expression by negatively regulating translation of target genes. Although the role of several miRNAs in vascular smooth muscle cells (VSMCs) has been extensively characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765242c66816adeaa800b5e33c72c1ca
https://pubmed.ncbi.nlm.nih.gov/32853091
https://pubmed.ncbi.nlm.nih.gov/32853091
Autor:
Daniele Catalucci, Nicolò Salvarani, Pierluigi Carullo, Michele Miragoli, M Barandalla Sobrados, Gianluigi Condorelli
Publikováno v:
European Heart Journal. 40
Background MicroRNAs (miRs) are regulators involved in several biological processes and have been recognized as potential novel therapeutic targets for the treatment and prevention of CDs. We previously demonstrated that the cardiac-enriched miR-133,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b33ad6702c512abf7c7ee9dce844e0
https://doi.org/10.1093/eurheartj/ehz745.0028
https://doi.org/10.1093/eurheartj/ehz745.0028
Autor:
Michele Miragoli, Paolo Kunderfranco, Carla Lucarelli, Matteo Dal Ferro, Giuseppe Faggian, Simone Serio, Gianfranco Sinagra, Paolo Vezzoni, Marianna Paulis, Gianluigi Condorelli, Alberto Forni, Alessandro Bertero, Nicolò Salvarani, Veronica Larcher, Charles E. Murry, Elisa Di Pasquale, Silvia Crasto
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Mutations in LMNA, which encodes the nuclear proteins Lamin A/C, can cause cardiomyopathy and conduction disorders. Here, we employ induced pluripotent stem cells (iPSCs) generated from human cells carrying heterozygous K219T mutation on LMNA to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c9451d24c9c25453be5b9e4a809317
http://hdl.handle.net/10044/1/97602
http://hdl.handle.net/10044/1/97602
Autor:
Gianluigi Condorelli, Reza Gharibi, Hamid Yeganeh, Elisa Di Pasquale, Nicolò Salvarani, Nafiseh Baheiraei, Michele Miragoli
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:1398-1407
In first part of this experiment, biocompatibility of the newly developed electroactive polyurethane/siloxane films containing aniline tetramer moieties was demonstrated with proliferation and differentiation of C2C12 myoblasts. Here we further asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e18d6a5ecbee7ddd3138b3705f1f14
https://doi.org/10.1002/jbm.a.35669
https://doi.org/10.1002/jbm.a.35669
Autor:
Gianluigi Condorelli, Michele Miragoli, Nafiseh Baheiraei, Hamid Yeganeh, Nicolò Salvarani, Elisa Di Pasquale, Reza Gharibi
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:775-787
Tissue-engineered cardiac patch aims at regenerating an infarcted heart by improving cardiac function and providing mechanical support to the diseased myocardium. In order to take advantages of electroactivity, a new synthetic method was developed fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20402b9ae6b4cac69d698d820e21f7b1
https://doi.org/10.1002/jbm.a.35612
https://doi.org/10.1002/jbm.a.35612