Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicolò Maganzini"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Biosensors using ligand-receptor binding tend to operate under equilibrium conditions, but this can make real-time monitoring challenging. Here the authors provide a theoretical foundation for biosensing where ligand concentrations can be continuousl
Externí odkaz:
https://doaj.org/article/b1510972f66c4321abf414668d57e227
Autor:
Amani A. Hariri, Sharon S. Newman, Steven Tan, Dan Mamerow, Alexandra M. Adams, Nicolò Maganzini, Brian L. Zhong, Michael Eisenstein, Alexander R. Dunn, H. Tom Soh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
A major challenge of enzyme-linked immunosorbent assays is discriminating true signal from non-specific binding. Here the authors present a Single-Molecule Colocalization Assay (SiMCA) which eliminates such effects, enabling reproducible detection of
Externí odkaz:
https://doaj.org/article/18c976fb74b244c38652006166953114
Autor:
Ian A.P. Thompson, Jason Saunders, Liwei Zheng, Amani A. Hariri, Nicolò Maganzini, Alyssa P. Cartwright, Jing Pan, Michael Eisenstein, Hyongsok Tom Soh
We present a generalizable approach for designing biosensors that can continuously detect specific biomarkers in real time and without sample preparation. This is achieved by converting existing antibodies into target-responsive “antibody-switches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610e44a052b17224fec28f4f76833f56
https://doi.org/10.1101/2023.03.07.531602
https://doi.org/10.1101/2023.03.07.531602
Autor:
Amani A. Hariri, Alyssa P. Cartwright, Constantin Dory, Yasser Gidi, Steven Yee, Kaiyu Fu, Kiyoul Yang, Diana Wu, Ian A. P. Thompson, Nicolò Maganzini, Trevor Feagin, Brian E. Young, Behrad Habib Afshar, Michael Eisenstein, Michel Digonnet, Jelena Vuckovic, H. Tom Soh
Current technology for measuring specific biomarkers – continuously in complex samples, without sample preparation – is limited to just handful of molecules such as glucose and blood oxygen. In this work, we present the first optical biosensor sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53384f8ef1ef6e4d53c28d5c41d226d6
https://doi.org/10.1101/2023.03.03.531030
https://doi.org/10.1101/2023.03.03.531030
Almost all biosensors that use ligand-receptor binding operate under equilibrium conditions. However, at low ligand concentrations, the equilibration with the receptor (e.g., antibodies and aptamers) become slow and thus equilibrium-based biosensors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a126405a5172244c17d39c2a8f089e7a
https://doi.org/10.1101/2022.03.26.485941
https://doi.org/10.1101/2022.03.26.485941
Autor:
Amani A. Hariri, Sharon S. Newman, Steven Tan, Dan Mamerow, Alexandra M. Adams, Nicolò Maganzini, Brian L. Zhong, Michael Eisenstein, Alexander R. Dunn, H. Tom Soh
Publikováno v:
Nature communications. 13(1)
Enzyme-linked immunosorbent assays (ELISAs) are a cornerstone of modern molecular detection, but the technique still faces notable challenges. One of the biggest problems is discriminating true signal generated by target molecules versus non-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e34425a9fea39d29616d1c497f44344
https://pubmed.ncbi.nlm.nih.gov/36097164
https://pubmed.ncbi.nlm.nih.gov/36097164
Autor:
Kaiyu Fu, Ji‐Won Seo, Vladimir Kesler, Nicolo Maganzini, Brandon D. Wilson, Michael Eisenstein, Boris Murmann, H. Tom Soh
Publikováno v:
Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)
Abstract Electrochemical biosensors hold the exciting potential to integrate molecular detection with signal processing and wireless communication in a miniaturized, low‐cost system. However, as electrochemical biosensors are miniaturized to the mi
Externí odkaz:
https://doaj.org/article/7cfaa41d881a4643a47e9146153e2ce2