Zobrazeno 1 - 10
of 525
pro vyhledávání: '"Nicodemi, M."'
Autor:
Brackley, C. A., Johnson, J., Michieletto, D., Morozov, A. N., Nicodemi, M., Cook, P. R., Marenduzzo, D.
Publikováno v:
Nucleus 9, 95 (2018)
Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is t
Externí odkaz:
http://arxiv.org/abs/2010.02548
Autor:
Brackley, C. A., Johnson, J., Michieletto, D., Morozov, A. N., Nicodemi, M., Cook, P. R., Marenduzzo, D.
Publikováno v:
Phys. Rev. Lett. 119, 138101 (2017)
We propose a model for the formation of chromatin loops based on the diffusive sliding of a DNA-bound factor which can dimerise to form a molecular slip-link. Our slip-links mimic the behaviour of cohesin-like molecules, which, along with the CTCF pr
Externí odkaz:
http://arxiv.org/abs/1612.07256
Publikováno v:
Physical Review E 80 (3), 031919 (2009)
In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation, each cell of an aggregate defines an inner and an outer side by brea
Externí odkaz:
http://arxiv.org/abs/1002.1558
Publikováno v:
Phys. Rev. E 84, 041308 (2011)
The non-equilibrium transition from a fluid-like state to a disordered solid-like state, known as the jamming transition, occurs in a wide variety of physical systems, such as colloidal suspensions and molecular fluids, when the temperature is lowere
Externí odkaz:
http://arxiv.org/abs/0912.3140
Autor:
Scialdone, A., Nicodemi, M.
Publikováno v:
PLoS Comp.Bio. 4, e1000244 (2008)
At the onset of X Chromosomes Inactivation, the vital process whereby female mammal cells equalize X products with respect to males, the X chromosomes are colocalized along their Xic (X-Inactivation Center) regions. The mechanism inducing recognition
Externí odkaz:
http://arxiv.org/abs/0910.2436
Publikováno v:
Genetics 179, 717 (2008)
A general model for the early recognition and colocalization of homologous DNA sequences is proposed. We show, on a thermodynamic ground, how the distance between two homologous DNA sequences is spontaneously regulated by the concentration and affini
Externí odkaz:
http://arxiv.org/abs/0809.4788
Autor:
Nicodemi, M., Prisco, A.
Publikováno v:
Phys. Rev. Lett. 98, 108104 (2007)
In mammals, dosage compensation of X linked genes in female cells is achieved by inactivation of one of their two X chromosomes which is randomly chosen. The earliest steps in X-inactivation (XCI), namely the mechanism whereby cells count their X chr
Externí odkaz:
http://arxiv.org/abs/0801.2730
Publikováno v:
Phys. Rev. E 73, 026123 (2006)
In order to characterize landslide frequency-size distributions and individuate hazard scenarios and their possible precursors, we investigate a cellular automaton where the effects of a finite driving rate and the anisotropy are taken into account.
Externí odkaz:
http://arxiv.org/abs/physics/0603100
Publikováno v:
Geophys. Rev. Lett. 33, L01403 (2006)
Landslide inventories show that the statistical distribution of the area of recorded events is well described by a power law over a range of decades. To understand these distributions, we consider a cellular automaton to model a time and position dep
Externí odkaz:
http://arxiv.org/abs/physics/0603094
Publikováno v:
Phys. Rev. Lett. 96, 051102 (2006)
Earthquakes and solar flares are phenomena involving huge and rapid releases of energy characterized by complex temporal occurrence. By analysing available experimental catalogs, we show that the stochastic processes underlying these apparently diffe
Externí odkaz:
http://arxiv.org/abs/cond-mat/0602208