Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nico Scholz"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract The cell cycle is tightly regulated by protein phosphorylation and ubiquitylation events. During mitosis, the multi-subunit cullin-RING E3 ubiquitin ligase APC/c functions as a molecular switch which signals for one cell to divide into two d
Externí odkaz:
https://doaj.org/article/4bd0491964e24ab587654f7395042234
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Glioblastoma is the most common primary brain tumor in adults with poor overall outcome and 5-year survival of less than 5%. Treatment has not changed much in the last decade or so, with surgical resection and radio/chemotherapy being the main option
Externí odkaz:
https://doaj.org/article/0a0b8f771b0a488bb5fec83ede633f07
Programmed cell death is a complex and tightly regulated sequence of events that determines cell fate during tissue homeostasis, development, and pathogenesis. The small protein modifier ubiquitin mediates important regulatory functions during cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48170577f777bbcddb421fc9efe91cda
https://doi.org/10.1101/2023.02.17.528998
https://doi.org/10.1101/2023.02.17.528998
Mechanistic studies of how protein ubiquitylation regulates the cell cycle, in particular during mitosis, has provided unique insights which have contributed to the emergence of the ‘Ubiquitin code’. In contrast to RING E3 ubiquitin ligases such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae445b89b3e356d9ea8d3862aa2c0f4
https://doi.org/10.1101/2021.12.17.473173
https://doi.org/10.1101/2021.12.17.473173
Autor:
Georgina Berridge, Janic Le Pen, Juliusz Mieszczanek, Lee D. Harris, Benedikt M. Kessler, Natalie Vaughan, Simon J. Davis, Mariann Bienz, Julien D.F. Licchesi, Nico Scholz
Publikováno v:
Harris, L D, Le Pen, J, Scholz, N, Mieszczanek, J, Vaughan, N, Davis, S, Berridge, G, Kessler, B, Bienz, M & Licchesi, J 2021, ' The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1 ', Journal of Biological Chemistry, vol. 296, no. 1, 100246 . https://doi.org/10.1074/jbc.RA120.015162
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Ubiquitin is a versatile post-translational modification which is covalently attached to protein targets either as a single moiety or as a ubiquitin chain. In contrast to K48 and K63- linked chains which have been extensively studied, the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bf631083b388fa81a2e5c8a620dc01
https://purehost.bath.ac.uk/ws/files/217198202/J._Biol._Chem._2020_Harris_jbc.RA120.015162.pdf
https://purehost.bath.ac.uk/ws/files/217198202/J._Biol._Chem._2020_Harris_jbc.RA120.015162.pdf
Publikováno v:
Frontiers in Oncology
Scholz, N, Kurian, K M, Siebzehnrubl, F A & Licchesi, J 2020, ' Targeting the Ubiquitin System in Glioblastoma ', Frontiers in Oncology, vol. 10, 574011 . https://doi.org/10.3389/fonc.2020.574011
Frontiers in Oncology, Vol 10 (2020)
Scholz, N, Kurian, K M, Siebzehnrubl, F A & Licchesi, J 2020, ' Targeting the Ubiquitin System in Glioblastoma ', Frontiers in Oncology, vol. 10, 574011 . https://doi.org/10.3389/fonc.2020.574011
Frontiers in Oncology, Vol 10 (2020)
Glioblastoma is the most common primary brain tumor in adults with poor overall outcome and 5-year survival of less than 5%. Treatment has not changed much in the last decade or so, with surgical resection and radio/chemotherapy being the main option
Publikováno v:
Electrophoresis. 40(7)
Multidimensional separation techniques play an increasingly important role in separation science, especially for the analysis of complex samples such as proteins. The combination of reversed-phase liquid chromatography in the nanoscale and CZE is esp