Mechanism of action of 4-substituted phenols to induce vitiligo and antimelanoma immunity

Autor: Arthur Kammeyer, Rosalie M. Luiten, Nico P.M. Smit, Sebas D. Pronk, Danielle Ratsma, Walbert J. Bakker, Karin J. Willemsen, Wouter Ouwerkerk

Publikováno v: Pigment Cell & Melanoma Research
Pigment Cell and Melanoma Research, 32(4), 540-552
Pigment cell & melanoma research, 32(4), 540-552. Wiley-Blackwell

Monobenzone is a 4‐substituted phenol that can induce vitiligo and antimelanoma immunity. We investigated the influence of the chemical structure on the biological activity of a series of structurally related 4‐substituted phenols. All phenols in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afb9fa74ef3886ed66d615a1816aba1
https://doi.org/10.1111/pcmr.12774

Metrological traceability and harmonization of medical tests: a quantum leap forward is needed to keep pace with globalization and stringent IVD-regulations in the 21st century!

Autor: Nico P.M. Smit, Philippe Gillery, Christa M. Cobbaert

Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM), 56(10), 1598-1602
Clinical Chemistry and Laboratory Medicine (CCLM)

In our efforts to advance the profession and practice of clinical laboratory medicine, strong coordination and collaboration are needed more than ever before. At the dawn of the 21st century, medical laboratories are facing many unmet clinical needs,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473fd2cf94432d421debb708a29d9400
https://www.degruyter.com/downloadpdf/j/cclm.2018.56.issue-10/cclm-2018-0343/cclm-2018-0343.pdf

Robust and Accurate 2-Year Performance of a Quantitative Mass Spectrometry-Based Apolipoprotein Test in a Clinical Chemistry Laboratory

Autor: Mervin M Pieterse, Arnoud van der Laarse, Christa M. Cobbaert, Fred P.H.T.M. Romijn, Yuri E. M. van der Burgt, Nico P.M. Smit, L. Renee Ruhaak

Publikováno v: Clinical Chemistry, 64(4), 747-749

To the Editor: We previously described a multiplex liquid chromatography–mass spectrometry (LC-MS)1 method for the quantification of 6 apolipoproteins (apo): A-I, B, C-I, C-II, C-III, and E (1). Analytical method validation was performed according

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e51ac9acfe1c2301f2c1bd218572e0
https://hdl.handle.net/1887/77615

Detecting molecular forms of antithrombin by LC-MRM-MS: defining the measurands

Autor: Christa M. Cobbaert, Piet Meijer, Nico P.M. Smit, Fred P.H.T.M. Romijn, Moniek P.M. de Maat, Cornelis Kluft, Mervin M Pieterse, L. Renee Ruhaak, Fred J. L. M. Haas, Arnoud van der Laarse, Jean Amiral

Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM), 56(10), 1704-1714
Clinical Chemistry and Laboratory Medicine (CCLM)

Background: Antithrombin (AT) is a critical regulator of coagulation, and its overall activity is typically measured using functional tests. A large number of molecular forms of AT have been identified and each individual carries multiple molecular p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38672f568861f59dee086a87d8c00576
https://pubmed.ncbi.nlm.nih.gov/29708875

ASSOCIATION OF BASELINE APOLIPOPROTEIN B AND FRIEDEWALD LDLC WITH LONG-TERM RE-INFARCTION IN HYPERTRIGLYCERIDEMIC PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION

Autor: Fred P.H.T.M. Romijn, M.J. Schalij, Y.E.M. van der Burgt, A. van der Laarse, Nico P.M. Smit, Maaike P. J. Hermans, Wouter Jukema, Christa M. Cobbaert

Publikováno v: Atherosclerosis, 252, E186-E186

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da736a2d589c00cfb13340f5a0faf0b
http://hdl.handle.net/1887/112571