Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Nico Lakenberg"'
Autor:
Thanh T. Hoang, Yunsung Lee, Daniel L. McCartney, Elin T.G. Kersten, Christian M. Page, Paige M. Hulls, Mikyeong Lee, Rosie M. Walker, Charles E. Breeze, Brian D. Bennett, Adam B. Burkholder, James Ward, Anne Lise Brantsæter, Ida H. Caspersen, Alison A. Motsinger-Reif, Marie Richards, Julie D. White, Shanshan Zhao, Rebecca C. Richmond, Maria C. Magnus, Gerard H. Koppelman, Kathryn L. Evans, Riccardo E. Marioni, Siri E. Håberg, Stephanie J. London, Bastiaan Heijmans, Peter ’t Hoen, Joyce van Meurs, Rick Jansen, Lude Franke, Dorret Boomsma, René Pool, Jenny van Dongen, Jouke Hottenga, Marleen van Greevenbroek, Coen Stehouwer, Carla van der Kallen, Casper Schalkwijk, Cisca Wijmenga, Sasha Zhernakova, Ettje Tigchelaar, P. Eline Slagboom, Marian Beekman, Joris Deelen, Diana Van Heemst, Jan Veldink, Leonard van den Berg, Cornelia van Duijn, Bert Hofman, Aaron Isaacs, André Uitterlinden, P. Mila Jhamai, Michael Verbiest, H. Eka Suchiman, Marijn Verkerk, Ruud van der Breggen, Jeroen van Rooij, Nico Lakenberg, Hailiang Mei, Maarten van Iterson, Michiel van Galen, Jan Bot, Dasha Zhernakova, Peter van ‘t Hof, Patrick Deelen, Irene Nooren, Matthijs Moed, Martijn Vermaat, René Luijk, Marc Bonder, Freerk van Dijk, Wibowo Arindrarto, Szymon Kielbasa, Morris Swertz, Erik van Zwet
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104956- (2024)
Summary: Background: Smoking impacts DNA methylation, but data are lacking on smoking-related differential methylation by sex or dietary intake, recent smoking cessation (
Externí odkaz:
https://doaj.org/article/3985b627485b4ff999b2ec073dfaf4e4
Autor:
Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Nico Lakenberg, Eka Suchiman, Hailiang Mei, Margreet Kloppenburg, Rob G. H. H. Nelissen, Ingrid Meulenbelt
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1356 (2021)
Objective: To identify and validate circulating micro RNAs (miRNAs) that mark gene expression changes in articular cartilage early in osteoarthritis (OA) pathophysiology process. Methods: Within the ongoing RAAK study, human preserved OA cartilage an
Externí odkaz:
https://doaj.org/article/9a0de23279b2478db5f07764f3c537e7
Autor:
Nils Bomer, Frederique M F Cornelis, Yolande F M Ramos, Wouter den Hollander, Nico Lakenberg, Ruud van der Breggen, Lies Storms, P Eline Slagboom, Rik J U Lories, Ingrid Meulenbelt
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154999 (2016)
OBJECTIVE:To identify intrinsic differences in cartilage gene expression profiles between wild-type- and Dio2-/--mice, as a mechanism to investigate factors that contribute to prolonged healthy tissue homeostasis. METHODS:Previously generated microar
Externí odkaz:
https://doaj.org/article/aac85a617a36467eac85fee1ee4b12cc
Autor:
Yolande F M Ramos, Wouter den Hollander, Judith V M G Bovée, Nils Bomer, Ruud van der Breggen, Nico Lakenberg, J Christiaan Keurentjes, Jelle J Goeman, P Eline Slagboom, Rob G H H Nelissen, Steffan D Bos, Ingrid Meulenbelt
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103056 (2014)
ObjectiveIdentify gene expression profiles associated with OA processes in articular cartilage and determine pathways changing during the disease process.MethodsGenome wide gene expression was determined in paired samples of OA affected and preserved
Externí odkaz:
https://doaj.org/article/2fa3036c8c66493fa4581fdf30a306d5
Autor:
Evelyn Houtman, Margo Tuerlings, H Eka D Suchiman, Nico Lakenberg, Frederique M F Cornelis, Hailiang Mei, Demiën Broekhuis, Rob G H H Nelissen, Rodrigo Coutinho de Almeida, Yolande F M Ramos, Rik J Lories, Luis J Cruz, Ingrid Meulenbelt
Publikováno v:
Rheumatology. OXFORD UNIV PRESS
Rheumatology
Rheumatology
Objectives To investigate whether the deiodinase inhibitor iopanoic acid (IOP) has chondroprotective properties, a mechanical stress induced model of human aged explants was used to test both repeated dosing and slow release of IOP. Methods Human ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5de7f0edc2ce0e93b2c98cd9f2a801
https://lirias.kuleuven.be/handle/20.500.12942/696032
https://lirias.kuleuven.be/handle/20.500.12942/696032
Autor:
Rodrigo Coutinho de Almeida, Margo Tuerlings, Yolande Ramos, Wouter Den Hollander, Eka Suchiman, Nico Lakenberg, Rob (RGHH) Nelissen, Hailiang Mei, Ingrid Meulenbelt
Publikováno v:
Rheumatology. OXFORD UNIV PRESS
Rheumatology
Rheumatology
Objectives To present an unbiased approach to identify positional transcript single nucleotide polymorphisms (SNPs) of osteoarthritis (OA) risk loci by allelic expression imbalance (AEI) analyses using RNA sequencing of articular cartilage and subcho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0eced72277c3a1d0ddd87c3d10d122
http://hdl.handle.net/1887/3513940
http://hdl.handle.net/1887/3513940
Autor:
Yolande F M Ramos, Ingrid Meulenbelt, Rob G H H Nelissen, E. Houtman, Nico Lakenberg, Enrike van der Linden-van der Zwaag, Marcella van Hoolwerff, H. Eka D. Suchiman
Publikováno v:
Rheumatology and Therapy
Rheumatology and Therapy, 8, 499-515. SPRINGER
Rheumatology and Therapy, 8, 499-515. SPRINGER
Introduction Likely due to ignored heterogeneity in disease pathophysiology, osteoarthritis (OA) has become the most common disabling joint disease, without effective disease-modifying treatment causing a large social and economic burden. In this stu
Autor:
Rodrigo Coutinho de Almeida, Nico Lakenberg, H. Eka D. Suchiman, Ingrid Meulenbelt, Hailiang Mei, Rob G H H Nelissen, Margreet Kloppenburg, Yolande F M Ramos
Publikováno v:
Biomolecules, 11(9). MDPI
Biomolecules
Volume 11
Issue 9
Biomolecules, Vol 11, Iss 1356, p 1356 (2021)
Biomolecules
Volume 11
Issue 9
Biomolecules, Vol 11, Iss 1356, p 1356 (2021)
Objective: To identify and validate circulating micro RNAs (miRNAs) that mark gene expression changes in articular cartilage early in osteoarthritis (OA) pathophysiology process. Methods: Within the ongoing RAAK study, human preserved OA cartilage an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54223cbbbf5d8ed6b303b8e65f480db
https://hdl.handle.net/1887/3239794
https://hdl.handle.net/1887/3239794
Autor:
Demien Broekhuis, Hailiang Mei, Yolande F M Ramos, Nico Lakenberg, H. Eka D. Suchiman, Ingrid Meulenbelt, Margo Tuerlings, Rodrigo Coutinho de Almeida, Davy Cats, Rob G H H Nelissen, Marcella van Hoolwerff, Jessica M van Bokkum
Publikováno v:
Rheumatology (Oxford, England). 61(7)
Objective To gain insight in the expression profile of long non-coding RNAs (lncRNAs) in OA subchondral bone. Methods RNA sequencing data of macroscopically preserved and lesioned OA subchondral bone of patients that underwent joint replacement surge
Autor:
Marcella van Hoolwerff, Ingrid Meulenbelt, Enrike van der Linden, Rob G H H Nelissen, Margo Tuerlings, Hailiang Mei, Yolande F M Ramos, Rodrigo Coutinho de Almeida, E. Suchiman, Nico Lakenberg, E. Houtman
Publikováno v:
Arthritis and Rheumatology, 73(5), 789-799. WILEY
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & Rheumatology (Hoboken, N.j.)
OBJECTIVE To identify key determinants of the interactive pathophysiologic processes in subchondral bone and cartilage in osteoarthritis (OA). METHODS We performed RNA sequencing on macroscopically preserved and lesional OA subchondral bone from pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863f53856521eb578c9dfdca0ffa50ee
http://hdl.handle.net/1887/3196095
http://hdl.handle.net/1887/3196095