Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nico Kress"'
Autor:
Min Huang, Grayson J. Ford, Ashley P. Mattey, Christopher Baldwin, James R. Marshall, William R. Birmingham, Lisa S. Seibt, Nico Kress, Lorna J. Hepworth, Sabine L. Flitsch, Nicholas J. Turner
Publikováno v:
Ford, G J, Kress, N, Mattey, A P, Hepworth, L J, Baldwin, C R, Marshall, J R, Seibt, L S, Huang, M, Birmingham, W R, Turner, N J & Flitsch, S L 2020, ' Synthesis of protected 3-aminopiperidine and 3-aminoazepane derivatives using enzyme cascades ', Chemical Communications, vol. 56, no. 57, pp. 7949-7952 . https://doi.org/10.1039/d0cc02976a
Chemical Communications
Chemical Communications
Multi-enzyme cascades utilising variants of galactose oxidase and imine reductase led to the successful conversion of N-Cbz-protected l-ornithinol and l-lysinol to l-3-N-Cbz-aminopiperidine and l-3-N-Cbz-aminoazepane respectively, in up to 54% isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8abc0d68bdcd5649bd9954bffa35c1
https://doi.org/10.1039/d0cc02976a
https://doi.org/10.1039/d0cc02976a
Publikováno v:
Current Opinion in Chemical Biology. 47:109-116
Enzymes are nature's powerful catalytic proteins to perform reactions with often outstanding activity, selectivity and specificity. Moreover, the access to non-natural functions of biocatalysts can be facilitated by enzyme engineering. While rational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fd715e7474cb20c6e91e578a58d344
https://doi.org/10.1016/j.cbpa.2018.09.010
https://doi.org/10.1016/j.cbpa.2018.09.010
Publikováno v:
ChemBioChem. 18:717-720
A deeper understanding of the >99 % S-selective reduction of both isomers of citral catalyzed by NCR ene reductase was achieved by active-site mutational studies and docking simulation. Though structurally similar, the E/Z isomers of citral showed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d29e68febd85d8f10ba7c96fc3529d
https://doi.org/10.1002/cbic.201700011
https://doi.org/10.1002/cbic.201700011
Autor:
William R. Birmingham, Sabine L. Flitsch, Juana Elizabeth Reyes Martinez, Fabio Parmeggiani, Nico Kress, Josef Voglmeir, Nicholas J. Turner, Kun Huang, Ashley P. Mattey, Peter Both, Gregory S Bulmer, Jolanda M. van Munster
Publikováno v:
Mattey, A, Birmingham, W R, Both, P, Kress, N, Huang, K, Van Munster, J M, Bulmer, G, Parmeggiani, F, Voglmeir, J, Reyes Martinez, J E, Turner, N J & Flitsch, S L 2019, ' Selective Oxidation of N-Glycolylneuraminic Acid Using an Engineered Galactose Oxidase Variant ', ACS Catalysis, vol. 9, no. 9, pp. 8208-8212 . https://doi.org/10.1021/acscatal.9b02873
N-Glycolylneuraminic acid (Neu5Gc) is a common cell surface ligand in animals which is not biosynthesized in humans but can be acquired in human tissue from dietary sources such as red meat. It is important to understand the relevance of this potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ef22d488fc4681a7072827bcf7a3ce
https://www.research.manchester.ac.uk/portal/en/publications/selective-oxidation-of-nglycolylneuraminic-acid-using-an-engineered-galactose-oxidase-variant(211706b8-d90f-4952-b533-24ba045e4689).html
https://www.research.manchester.ac.uk/portal/en/publications/selective-oxidation-of-nglycolylneuraminic-acid-using-an-engineered-galactose-oxidase-variant(211706b8-d90f-4952-b533-24ba045e4689).html
Autor:
Nico Kreß, Bernhard Hauer
Publikováno v:
BIOspektrum. 23:836-838
Biocatalysis can serve as a basis for the synthesis of structurally challenging valuable compounds. The synergistic use of biological and chemical knowledge represents a fruitful approach for finding starting points in the development of novel enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7516fcf2e1d508f6ff939e8e1713a12c
https://doi.org/10.1007/s12268-017-0878-1
https://doi.org/10.1007/s12268-017-0878-1
The squalene hopene cyclase from Alicyclobacillus acidocaldarius (AacSHC) is a highly efficient enzyme catalyst for stereoselective Bronsted acid catalysis. We engineered AacSHC to catalyze the selective Prins cyclization of citronellal. Four active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa58bbc3b6f396c2cf8171c63d4b597
https://pub.uni-bielefeld.de/record/2949716
https://pub.uni-bielefeld.de/record/2949716
Publikováno v:
ChemBioChem. 18:695-695
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37fed46e2c7fefe60f938ca6e7a3733a
https://doi.org/10.1002/cbic.201700163
https://doi.org/10.1002/cbic.201700163
Autor:
Nicole Schädel, Nico Kreß
Publikováno v:
Nachrichten aus der Chemie. 64:563-563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33ab66d963f629489ac020f42aafda0
https://doi.org/10.1002/nadc.20164051502
https://doi.org/10.1002/nadc.20164051502