Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nico Fricke"'
Autor:
Nico Fricke, Krishnan Raghunathan, Ajit Tiwari, Katherine M. Stefanski, Muthuraj Balakrishnan, Alex G. Waterson, Ricardo Capone, Hui Huang, Charles R. Sanders, Joshua A. Bauer, Anne K. Kenworthy
Publikováno v:
ACS Central Science, Vol 8, Iss 3, Pp 370-378 (2022)
Externí odkaz:
https://doaj.org/article/bcbf6e10de2f41239d8026b4d49b06a3
Autor:
Wooseong Kim, Guijin Zou, Wen Pan, Nico Fricke, Hammad A. Faizi, Soo Min Kim, Rajamohammed Khader, Silei Li, Kiho Lee, Iliana Escorba, Petia M. Vlahovska, Huajian Gao, Frederick M. Ausubel, Eleftherios Mylonakis
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Resistance or tolerance to traditional antibiotics is a challenging issue in antimicrobial chemotherapy. Moreover, traditional bactericidal antibiotics kill only actively growing bacterial cells, whereas nongrowing metabolically inactive cel
Externí odkaz:
https://doaj.org/article/4c6e5367321845828598c4354294512c
Autor:
Nico Fricke, Krishnan Raghunathan, Ajit Tiwari, Katherine M. Stefanski, Muthuraj Balakrishnan, Alex G. Waterson, Ricardo Capone, Hui Huang, Charles R. Sanders, Joshua A. Bauer, Anne K. Kenworthy
Publikováno v:
ACS central science. 8(3)
Plasma membrane organization profoundly impacts cellular functionality. A well-known mechanism underlying this organization is through nanoscopic clustering of distinct lipids and proteins in membrane rafts. Despite their physiological importance, ra
Autor:
Frederick M. Ausubel, Kiho Lee, Rajamohammed Khader, Wen Pan, Guijin Zou, Silei Li, Iliana Escorba, Nico Fricke, Wooseong Kim, Petia M. Vlahovska, Soo Min Kim, Eleftherios Mylonakis, Hammad A. Faizi, Huajian Gao
Publikováno v:
mBio, Vol 11, Iss 3, p e01140-20 (2020)
mBio
mBio, Vol 11, Iss 3 (2020)
mBio
mBio, Vol 11, Iss 3 (2020)
Membrane-damaging antimicrobial agents have great potential to treat multidrug-resistant or multidrug-tolerant bacteria against which conventional antibiotics are not effective. However, their therapeutic applications are often hampered due to their
Autor:
Charles R. Sanders, Nico Fricke, Anne K. Kenworthy, Arina Hadziselimovic, Ricardo Capone, Ajit Tiwari
Publikováno v:
Biophysical Journal. 118:392a
Autor:
Anne K. Kenworthy, Ricardo Capone, Ajit Tiwari, Krishnan Raghunathan, Hui Huang, Nico Fricke, Charles R. Sanders
Publikováno v:
Biophysical Journal. 118:77a
Autor:
Wooseong Kim, Nico Fricke, Huajian Gao, William M. Wuest, Erika E Csatary, Bumsup Kwon, Frederick M. Ausubel, Andrew D. Steele, Madeline M Dekarske, Elamparithi Jayamani, Wen Pan, Petia M. Vlahovska, Annie L. Conery, Wenpeng Zhu, Jake L Rosen, Beth Burgwyn Fuchs, Isabelle Sinitsa, Eleftherios Mylonakis
Conventional antibiotics are not effective in treating infections caused by drug-resistant or persistent nongrowing bacteria, creating a dire need for the development of new antibiotics. We report that the small molecule nTZDpa, previously characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f0e34866439648dea6accbe29a166e
https://europepmc.org/articles/PMC6468991/
https://europepmc.org/articles/PMC6468991/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The multifaceted involvement of GM1 as a ligand in many cellular functions has been well recognized. We find that GM1 readily desorbs from the membrane of cell-sized model biomimetic systems (giant unilamellar vesicles). The desorption i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f53af9a4a8b0b0cc311599b4d14a56f
https://hdl.handle.net/21.11116/0000-0001-610E-321.11116/0000-0001-802C-D
https://hdl.handle.net/21.11116/0000-0001-610E-321.11116/0000-0001-802C-D
Autor:
Kiho Lee, Andrew D. Steele, Petia M. Vlahovska, Beth Burgwyn Fuchs, Michael S. Gilmore, Nico Fricke, William M. Wuest, Annie L. Conery, Wen Pan, Wooseong Kim, Colleen E. Keohane, Huajian Gao, Wenpeng Zhu, Steven S. Shen, Eleftherios Mylonakis, Daria Van Tyne, Rajmohan Rajamuthiah, Frederick M. Ausubel, Gabriel L. Hendricks
Publikováno v:
Nature. 556(7699)
A challenge in the treatment of Staphylococcus aureus infections is the high prevalence of methicillin-resistant S. aureus (MRSA) strains and the formation of non-growing, dormant ‘persister’ subpopulations that exhibit high levels of tolerance t
Autor:
Frederick M. Ausubel, Annie L. Conery, Beth Burgwyn Fuchs, Nico Fricke, Elamparithi Jayamani, Eleftherios Mylonakis, Wooseong Kim, Rajmohan Rajamuthiah, Petia M. Vlahovska
Background: NH125, a known WalK inhibitor kills MRSA persisters. However, its precise mode of action is still unknown. Methods & results: The mode of action of NH125 was investigated by comparing its spectrum of antimicrobial activity and its effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a50c8b37b78bfe6c3cc834e0935a49
https://europepmc.org/articles/PMC4976882/
https://europepmc.org/articles/PMC4976882/