A comparison of four different models of acute respiratory distress syndrome in sheep

Autor: Monique Engel, Relana M. E. Nowacki, Elly M. Jonker, Daan Ophelders, Maria Nikiforou, Nico Kloosterboer, Luc J. I. Zimmermann, Dick A. van Waardenburg, Boris W. Kramer

Publikováno v: Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)

Abstract Background Acute respiratory distress syndrome (ARDS) can have various causes. The study objective was to investigate whether different pathophysiologic models of ARDS would show different respiratory, cardiovascular and inflammatory outcome

Externí odkaz: https://doaj.org/article/be332553941f4010994e4d6eb662711e

Smoking-Associated Exposure of Human Primary Bronchial Epithelial Cells to Aldehydes: Impact on Molecular Mechanisms Controlling Mitochondrial Content and Function

Autor: Christy B. M. Tulen, Evert Duistermaat, Johannes W. J. M. Cremers, Walther N. M. Klerx, Paul H. B. Fokkens, Naömi Weibolt, Nico Kloosterboer, Mieke A. Dentener, Eric R. Gremmer, Phyllis J. J. Jessen, Evi J. C. Koene, Lou Maas, Antoon Opperhuizen, Frederik-Jan van Schooten, Yvonne C. M. Staal, Alexander H. V. Remels

Publikováno v: Cells, Vol 11, Iss 21, p 3481 (2022)

Chronic obstructive pulmonary disease (COPD) is a devastating lung disease primarily caused by exposure to cigarette smoke (CS). During the pyrolysis and combustion of tobacco, reactive aldehydes such as acetaldehyde, acrolein, and formaldehyde are f

Externí odkaz: https://doaj.org/article/2858f0d527984676b53f121e83d3e3b9

Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis: A Potential Role for Plant Sterols

Autor: Charlotte van Gorp, Ilse H. de Lange, Owen B. Spiller, Frédéric Dewez, Berta Cillero Pastor, Ron M. A. Heeren, Lilian Kessels, Nico Kloosterboer, Wim G. van Gemert, Michael L. Beeton, Sarah J. Stock, Alan H. Jobe, Matthew S. Payne, Matthew W. Kemp, Luc J. Zimmermann, Boris W. Kramer, Jogchum Plat, Tim G. A. M. Wolfs

Publikováno v: Nutrients, Vol 11, Iss 5, p 968 (2019)

Chorioamnionitis, clinically most frequently associated with Ureaplasma, is linked to intestinal inflammation and subsequent gut injury. No treatment is available to prevent chorioamnionitis-driven adverse intestinal outcomes. Evidence is increasing

Externí odkaz: https://doaj.org/article/c9c4cfe62e41400ba4462aa01fb817a9

Protection of the ovine fetal gut against ureaplasma-induced chorioamnionitis: a potential role for plant sterols

Autor: Boris W. Kramer, Jogchum Plat, Matthew W. Kemp, Ron M. A. Heeren, Charlotte van Gorp, Wim G. van Gemert, Sarah J. Stock, Matthew S. Payne, Frédéric Dewez, Michael L. Beeton, Nico Kloosterboer, Berta Cillero Pastor, Alan H. Jobe, Lilian Kessels, Luc J. I. Zimmermann, Tim G. A. M. Wolfs, Owen B. Spiller, Ilse H. de Lange

Publikováno v: Nutrients
van Gorp, C, de Lange, I H, Spiller, O B, Dewez, F, Cillero Pastor, B, Heeren, R M A, Kessels, L, Kloosterboer, N, van Gemert, W G, Beeton, M L, Stock, S J, Jobe, A H, Payne, M S, Kemp, M W, Zimmermann, L J, Kramer, B W, Plat, J & Wolfs, T G A M 2019, ' Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis : A Potential Role for Plant Sterols ', Nutrients, vol. 11, no. 5 . https://doi.org/10.3390/nu11050968
Nutrients, 11(5):968, 1-21. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 11
Issue 5
Nutrients, Vol 11, Iss 5, p 968 (2019)

Chorioamnionitis, clinically most frequently associated with Ureaplasma, is linked to intestinal inflammation and subsequent gut injury. No treatment is available to prevent chorioamnionitis-driven adverse intestinal outcomes. Evidence is increasing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1268294232f335355ea6c189b718b9
https://orca.cardiff.ac.uk/id/eprint/122002/1/nutrients-11-00968.pdf

Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis

Autor: Birgit L. M. G. Senden-Gijsbers, Daan R. M. G. Ophelders, Nico Kloosterboer, Reint K. Jellema, Maria Nikiforou, Wilfred T. V. Germeraad, Tim G. A. M. Wolfs, Joris Vanderlocht, Mandy F. Joosten, Boris W. Kramer, Claire A. Chougnet

Publikováno v: Inflammatory Bowel Diseases, 21(9), 2026-2038. LIPPINCOTT WILLIAMS & WILKINS

Background Chorioamnionitis results from an infection of the fetal membranes and is associated with fetal adverse outcomes notably in the intestine. Using a translational ovine model, we showed that intra-amniotic exposure to inflammatory stimuli dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e784dff70dfc7703c650aed352b2d1
https://doi.org/10.1097/mib.0000000000000455