Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Niclas Lunder"'
Publikováno v:
Therapeutic Drug Monitoring. 41:396-400
Drugs may potentially adsorb to blood collection tubes containing gel separators in the preanalytical phase of therapeutic drug monitoring. The aim of this study was to compare measured concentrations of 28 psychoactive drugs and 13 metabolites in sp
Autor:
Silje Skrede, Niclas Lunder, Rolf K. Berge, Johan Fernø, Miguel López, María Jesús Vázquez, Carlos Dieguez, Sveinung Fjær, Vidar M. Steen, Tina Pavlin, Antonio Vidal-Puig
Publikováno v:
International Journal of Neuropsychopharmacology. 15:163-179
Metabolic adverse effects such as weight gain and dyslipidaemia represent a major concern in treatment with several antipsychotic drugs, including olanzapine. It remains unclear whether such metabolic side-effects fully depend on appetite-stimulating
Autor:
Niclas Lunder, Johan Fernø, Vidar M. Steen, Audun Osland Vik-Mo, Hege Wergedal, Miguel López, Silje Skrede, Carlos Dieguez, Goran Jassim, Rolf K. Berge, Antonio Vidal-Puig, María Jesús Vázquez
Publikováno v:
Psychopharmacology
Psychopharmacology; Vol 219
Psychopharmacology; Vol 219
Objective This study aims to investigate whether orexigenic antipsychotic drugs may induce dyslipidemia and glucose disturbances in female rats through direct perturbation of metabolically active peripheral tissues, independent of prior weight gain.
Publikováno v:
Therapeutic Drug Monitoring. 28:744-749
Aripiprazole is a new atypical antipsychotic drug with a partial agonist activity at dopamine 2 and serotonin 1A receptors. The metabolism of aripiprazole involves both cytochrome P450 2D6 (CYP2D6) and CYP3A4. This study investigated the pharmacokine
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 40(9)
The antipsychotic drug quetiapine has been approved for the treatment of unipolar and bipolar depression. The antidepressant activity is considered to be mediated by the active metabolite N-desalkylquetiapine, which is mainly formed by CYP3A4. Little
Autor:
Petter Moi, Marianne S. Nordlund, Bjørn Winther, Elisabeth Paus, J. Léon E. Reubsaet, Niclas Lunder
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(13)
The objective of this study was to develop a method using liquid chromatography with tandem mass spectrometric detection for the absolute quantification of the small cell lung cancer biomarker ProGRP in human serum, using its tryptic signature peptid
Autor:
Bjarte Håvik, Silje Skrede, Vidar M. Steen, Kjetil Berge, Oddrun Anita Gudbrandsen, Rolf K. Berge, Niclas Lunder, Johan Fernø, Goran Jassim, Audun Osland Vik-Mo, Sverre Mørk, Hyugo A. Jørgensen, Jo Erling Riise Waage
Publikováno v:
Psychopharmacology. 203(1)
Several antipsychotic drugs (APDs) have high propensity to induce weight gain and dyslipidemia in patients, with clozapine and olanzapine as the most potent drugs. These lipid-related effects have been attributed to drug-mediated blockade or antagoni
Publikováno v:
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 125(6)
Sales of herbal dietary supplements have increased dramatically. A patient case drew our attention to the problem of incomplete declaration of content.Two dietary supplements which the manufacturers claim to be natural, extremely fat-burning and ener
Autor:
Lars Gullestad, Ida Robertsen, Hege Christensen, Anders Åsberg, Nina K Næss, Pål Falck, Arne K. Andreassen, Niclas Lunder
Publikováno v:
Transplantation Research
Background In the early phases following heart transplantation a main challenge is to reduce the impact of acute rejections. Previous studies indicate that intracellular ciclosporin A (CsA) concentration may be a sensitive acute rejection marker in r