Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Niclas Kneisel"'
Autor:
Bernhard Radlwimmer, Gernot Poschet, Yonghe Wu, Karsten Hiller, Lidia Santos Silva, Peter Lichter, Yannic Nonnenmacher, Holger M. Becker, Magdalena Schlotter, Sean C. Sapcariu, Ann Christin Gaupel, Niclas Kneisel, Rüdiger Hell, Martina Seiffert
Publikováno v:
EMBO reports. 18:2172-2185
Elevated amino acid catabolism is common to many cancers. Here, we show that glioblastoma are excreting large amounts of branched‐chain ketoacids (BCKAs), metabolites of branched‐chain amino acid (BCAA) catabolism. We show that efflux of BCKAs, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e06ac8bc0b6eecda04079705afcd0bf
https://doi.org/10.15252/embr.201744154
https://doi.org/10.15252/embr.201744154
Autor:
Bernhard Radlwimmer, Mario Hlevnjak, Wei Wang, Kathrin V. Schmidt, M. Kirchgäßner, A. E. Lykkesfeldt, Verena Thewes, Guido Sauter, Martje Tönjes, Stefanie Heck, Ulrich Deuschle, Magdalena Schlotter, Hans-Peter Sinn, P. Windisch, Nathaniel Melling, Jürgen G. Okun, Peter Lichter, S. Kaulfuss, Andreas Schneeweiss, Yonghe Wu, Marc Zapatka, Niclas Kneisel, Reinhard Büttner, Ronald Simon, Tobias Anzeneder, H. Hess-Stumpp, Petra Schroeter
Publikováno v:
Oncogene. 36:4124-4134
Antiestrogen-resistant and triple-negative breast tumors pose a serious clinical challenge because of limited treatment options. We assessed global gene expression changes in antiestrogen-sensitive compared with antiestrogen-resistant (two tamoxifen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5113c500b31d5571ace1e5ec0ba2f1
https://doi.org/10.1038/onc.2017.32
https://doi.org/10.1038/onc.2017.32
Autor:
Simon, Raffel, Mattia, Falcone, Niclas, Kneisel, Jenny, Hansson, Wei, Wang, Christoph, Lutz, Lars, Bullinger, Gernot, Poschet, Yannic, Nonnenmacher, Andrea, Barnert, Carsten, Bahr, Petra, Zeisberger, Adriana, Przybylla, Markus, Sohn, Martje, Tönjes, Ayelet, Erez, Lital, Adler, Patrizia, Jensen, Claudia, Scholl, Stefan, Fröhling, Sibylle, Cocciardi, Patrick, Wuchter, Christian, Thiede, Anne, Flörcken, Jörg, Westermann, Gerhard, Ehninger, Peter, Lichter, Karsten, Hiller, Rüdiger, Hell, Carl, Herrmann, Anthony D, Ho, Jeroen, Krijgsveld, Bernhard, Radlwimmer, Andreas, Trumpp
Publikováno v:
Nature. 560(7718)
In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample DD06. Supplementary Data 4 has been added to the Supplementary Information of the original
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::898b3358465737146714ba41d5ad6159
https://pubmed.ncbi.nlm.nih.gov/29144447
https://pubmed.ncbi.nlm.nih.gov/29144447
Autor:
Petra Zeisberger, Patrizia Jensen, Sibylle Cocciardi, Lars Bullinger, Adriana Przybylla, Anne Flörcken, Jeroen Krijgsveld, Andreas Trumpp, Bernhard Radlwimmer, Gerhard Ehninger, Stefan Fröhling, Mattia Falcone, Carl Herrmann, Lital Adler, Patrick Wuchter, Jenny Hansson, Yannic Nonnenmacher, Gernot Poschet, Peter Lichter, Jörg Westermann, Anthony D. Ho, Martje Tönjes, Christoph Lutz, Rüdiger Hell, Carsten Bahr, Wei Wang, Andrea Barnert, Simon Raffel, Claudia Scholl, Ayelet Erez, Niclas Kneisel, Markus Sohn, Christian Thiede, Karsten Hiller
Publikováno v:
Nature. 551(7680)
The branched-chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer entities. However, the mechanistic role of BCAT1 in this process remains largely uncertain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebae6a75b572ad45ac83ce2de9d5c93
https://pubmed.ncbi.nlm.nih.gov/30069041
https://pubmed.ncbi.nlm.nih.gov/30069041
Autor:
Anita Schmitt, Lei Wang, Thomas Hoeger, Susanne Hofmann, Michael Schmitt, Carsten Mueller-Tidow, Bailin He, Brigitte Neuber, Niclas Kneisel
Publikováno v:
Blood. 134:3226-3226
Introduction Despite the encouraging outcome of anti-CD19 chimeric antigen receptor T (CAR T) cell therapy in patients with B cell malignancies, CAR T cell persistence remains a major clinical challenge. Activation-induced cell death (AICD) is a prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7ddca19b8f285ab4e47d9f5680b15a
https://doi.org/10.1182/blood-2019-122833
https://doi.org/10.1182/blood-2019-122833
Autor:
Hilmar Bading, Giles E. Hardingham, Anna M. Hagenston, Marc-Andre Martel, Yan-Wei Tan, David J. A. Wyllie, Paul Skehel, Jing-Dan Qiu, Niclas Kneisel
Publikováno v:
Qiu, J, Tan, Y-W, Hagenston, A M, Martel, M-A, Kneisel, N, Skehel, P, Wyllie, D, Bading, H & Hardingham, G 2013, ' Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals ', Nature Communications, vol. 4, no. n/a, 2034 . https://doi.org/10.1038/ncomms3034
Nature Communications
Nature Communications
The recent identification of the mitochondrial Ca2+ uniporter gene (Mcu/Ccdc109a) has enabled us to address its role, and that of mitochondrial Ca2+ uptake, in neuronal excitotoxicity. Here we show that exogenously expressed Mcu is mitochondrially lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fff9e7ac7a72a4b0d44534f9a40f021
https://www.pure.ed.ac.uk/ws/files/8318193/Mitochondrial_calcium_uniporter_Mcu_controls_excitotoxicity_and_is_transcriptionally_repressed_by_neuroprotective_nuclear_calcium_signals.pdf
https://www.pure.ed.ac.uk/ws/files/8318193/Mitochondrial_calcium_uniporter_Mcu_controls_excitotoxicity_and_is_transcriptionally_repressed_by_neuroprotective_nuclear_calcium_signals.pdf
