Stabilization of Tryptophan Hydroxylase 2 by L-Phenylalanine Induced Dimerization

Autor: Günther H.J. Peters, Kasper Damgaard Tidemand, Pernille Harris, Hans Erik Mølager Christensen, Niclas Hoeck, Jane Boesen

Publikováno v: Tidemand, K D, Christensen, H E M, Hoeck, N, Harris, P, Boesen, J & Peters, G H J 2016, ' Stabilization of Tryptophan Hydroxylase 2 by L-Phenylalanine Induced Dimerization ', F E B S Open Bio, vol. 6, no. 10, pp. 987-999 . https://doi.org/10.1002/2211-5463.12100
FEBS Open Bio

Tryptophan hydroxylase 2 (TPH2) catalyses the initial and rate-limiting step in the biosynthesis of serotonin, which is associated with a variety of disorders such as depression, obsessive compulsive disorder, and schizophrenia. Full-length TPH2 is p

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https://orbit.dtu.dk/en/publications/fab2fb05-4db6-4ed0-9bfd-0dd3381553ac