Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Nicky Thomas"'
Autor:
Legesse Garedew Kifelew, Morgyn S. Warner, Sandra Morales, David L. Gordon, Nicky Thomas, James G. Mitchell, Peter G. Speck
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Complications of diabetes, such as diabetic foot ulcers (DFUs), are common, multifactorial in origin, and costly to treat. DFUs are the cause of nearly 90% of limb amputations among persons with diabetes. In most chronic infections such as D
Externí odkaz:
https://doaj.org/article/5050fe918ace48169c8715d8007e0510
Autor:
Anam Ahsan, Nicky Thomas, Timothy J. Barnes, Santhni Subramaniam, Thou Chen Loh, Paul Joyce, Clive A. Prestidge
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 396 (2024)
The opportunistic bacteria growing in biofilms play a decisive role in the pathogenesis of chronic infectious diseases. Biofilm-dwelling bacteria behave differently than planktonic bacteria and are likely to increase resistance and tolerance to antim
Externí odkaz:
https://doaj.org/article/9d0e086c65b44475b36d6aae706253b7
Publikováno v:
BJGP Open, Vol 7, Iss 3 (2023)
Background: Parents of children diagnosed with intellectual disability are at increased risk of mental and physical health difficulties compared with other parents. They are likely to regularly seek medical treatment for their health concerns from ge
Externí odkaz:
https://doaj.org/article/68e2cb86caed4f359cac3998955873cf
Autor:
Elizabeth Bailey, Samantha Nightingale, Nicky Thomas, Dawn Coleby, Toity Deave, Trudy Goodenough, Samuel Ginja, Raghu Lingam, Sally Kendall, Crispin Day, Jane Coad
Publikováno v:
JMIR mHealth and uHealth, Vol 10, Iss 11, p e32757 (2022)
BackgroundInternationally, there is increasing emphasis on early support for pregnant women to optimize the health and development of mothers and newborns. To increase intervention reach, digital and app-based interventions have been advocated. There
Externí odkaz:
https://doaj.org/article/4acf203f54c345c58e38266e8debbf5a
Autor:
Muhammed Awad, Zlatko Kopecki, Timothy J. Barnes, Anthony Wignall, Paul Joyce, Nicky Thomas, Clive A. Prestidge
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 305 (2023)
Cutaneous chronic wounds impose a silent pandemic that affects the lives of millions worldwide. The delayed healing process is usually complicated by opportunistic bacteria that infect wounds. Staphylococcus aureus is one of the most prevalent bacter
Externí odkaz:
https://doaj.org/article/36805d2a96dd4fdb8e08bba5961b25a2
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2124 (2022)
The looming antimicrobial resistance pandemic has encouraged the investigation of antimicrobial photodynamic therapy (aPDT) as a promising technology to combat recalcitrant bacterial infections caused by antibiotic resistant strains. Here, we report
Externí odkaz:
https://doaj.org/article/a353b11937954471b3cc8ec000cf6a06
Publikováno v:
Metals, Vol 11, Iss 7, p 998 (2021)
Leaded brass alloys with high zinc content are classified as dual-phase (α-β′) brass alloys. For these alloys, α-β′ phase transformation induced by thermomechanical processing (TMP) is expected to play a significant role not only in the forma
Externí odkaz:
https://doaj.org/article/7c465f213a3d493da2d37bdc4c21eb58
Autor:
Ruba Almasri, Paul Joyce, Hayley B. Schultz, Nicky Thomas, Kristen E. Bremmell, Clive A. Prestidge
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 687 (2020)
The unique nanostructured matrix obtained by silica-lipid hybrids (SLHs) is well known to improve the dissolution, absorption, and bioavailability of poorly water-soluble drugs (PWSDs). The aim of this study was to investigate the impact of: (i) drug
Externí odkaz:
https://doaj.org/article/db30e6ba7d6545c48f344616fd82a8de
Autor:
Legesse Garedew Kifelew, Morgyn S. Warner, Sandra Morales, Nicky Thomas, David L. Gordon, James G. Mitchell, Peter G. Speck
Publikováno v:
Viruses, Vol 12, Iss 5, p 559 (2020)
The efficacy of phages in multispecies infections has been poorly examined. The in vitro lytic efficacies of phage cocktails AB-SA01, AB-PA01, which target Staphylococcus aureus and Pseudomonas aeruginosa, respectively, and their combination against
Externí odkaz:
https://doaj.org/article/45c9ea3e0e3946049928101ba76d260e
Autor:
Mian L. Ooi, Katharina Richter, Amanda J. Drilling, Nicky Thomas, Clive A. Prestidge, Craig James, Stephen Moratti, Sarah Vreugde, Alkis J. Psaltis, Peter-John Wormald
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Objectives: Increasing antimicrobial resistance has presented new challenges to the treatment of recalcitrant chronic rhinosinusitis fuelling a continuous search for novel antibiofilm agents. This study aimed to assess the safety and efficacy of Chit
Externí odkaz:
https://doaj.org/article/b0fde16dc48f43239ea20816adb62bb5