Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Nicky J Welton"'
Autor:
Nicky J Welton, Sofia Dias, Bruce Guthrie, Srinivasa Vittal Katikireddi, Katie Gillies, David A McAllister, Frances Mair, Sarah H Wild, Peter Hanlon, Elaine W Butterly, Emilia Harding, Jennifer Lees, Jamie Crowther
Publikováno v:
BMJ Medicine, Vol 3, Iss 1 (2024)
Objectives To assess whether age, sex, comorbidity count, and race and ethnic group are associated with the likelihood of trial participants not being enrolled in a trial for any reason (ie, screen failure).Design Bayesian meta-analysis of individual
Externí odkaz:
https://doaj.org/article/51a6d450e5064446aa2b10256d02612b
Autor:
Peter Hanlon, Elaine W Butterly, Anoop Sv Shah, Laurie J Hannigan, Jim Lewsey, Frances S Mair, David M Kent, Bruce Guthrie, Sarah H Wild, Nicky J Welton, Sofia Dias, David A McAllister
Publikováno v:
PLoS Medicine, Vol 20, Iss 6, p e1004176 (2023)
BackgroundPeople with comorbidities are underrepresented in clinical trials. Empirical estimates of treatment effect modification by comorbidity are lacking, leading to uncertainty in treatment recommendations. We aimed to produce estimates of treatm
Externí odkaz:
https://doaj.org/article/fa16bc9ce7af4bb2b3525ec362ce6eb3
Autor:
Elaine W Butterly, Peter Hanlon, Anoop S V Shah, Laurie J Hannigan, Emma McIntosh, Jim Lewsey, Sarah H Wild, Bruce Guthrie, Frances S Mair, David M Kent, Sofia Dias, Nicky J Welton, David A McAllister
Publikováno v:
PLoS Medicine, Vol 20, Iss 1, p e1004154 (2023)
BackgroundHealth-related quality of life metrics evaluate treatments in ways that matter to patients, so are often included in randomised clinical trials (hereafter trials). Multimorbidity, where individuals have 2 or more conditions, is negatively a
Externí odkaz:
https://doaj.org/article/b722117687da4beba10e5d9bd5217e8d
Autor:
Nicky J Welton, Sofia Dias, Rod S Taylor, Bruce Guthrie, Katie Gillies, David A McAllister, Frances S Mair, Sarah H Wild, Peter Hanlon, Jennifer S Lees, Elaine W Butterly
Publikováno v:
BMJ Medicine, Vol 1, Iss 1 (2022)
Objectives To estimate the association between individual participant characteristics and attrition from randomised controlled trials.Design Meta-analysis of individual participant level data (IPD).Data sources Clinical trial repositories (Clinical S
Externí odkaz:
https://doaj.org/article/5f2578e48549474bb55b99026da7089e
Autor:
Nicky J Welton, Harish Nair, David A McAllister, Harry Campbell, Amir Kirolos, Alisha Khanna, Rachel M Blacow, Arun Parajuli
Publikováno v:
BMJ Global Health, Vol 6, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/a9218d749e9b4200bb2592fb853b8f06
Autor:
Kyla H Thomas, Michael N Dalili, José A López-López, Edna Keeney, David Phillippo, Marcus R Munafò, Matt Stevenson, Deborah M Caldwell, Nicky J Welton
Publikováno v:
Health Technology Assessment, Vol 25, Iss 59 (2021)
Background: Cigarette smoking is one of the leading causes of early death. Varenicline [Champix (UK), Pfizer Europe MA EEIG, Brussels, Belgium; or Chantix (USA), Pfizer Inc., Mission, KS, USA], bupropion (Zyban; GlaxoSmithKline, Brentford, UK) and ni
Externí odkaz:
https://doaj.org/article/7babc5fdcdad4fa9a5bc0152ec687f84
Autor:
Deborah M Caldwell, Sarah R Davies, Joanna C Thorn, Jennifer C Palmer, Paola Caro, Sarah E Hetrick, David Gunnell, Sumayya Anwer, José A López-López, Clare French, Judi Kidger, Sarah Dawson, Rachel Churchill, James Thomas, Rona Campbell, Nicky J Welton
Publikováno v:
Public Health Research, Vol 9, Iss 8 (2021)
Background: Schools in the UK increasingly have to respond to anxiety, depression and conduct disorder as key causes of morbidity in children and young people. Objective: The objective was to assess the comparative effectiveness of educational settin
Externí odkaz:
https://doaj.org/article/970b421f819544c4a42f1dde155fa097
Autor:
Nicky J Welton, Peter Vickerman, Katherine M E Turner, Christine Johnston, Katharine Jane Looker, Charlotte James, Marie-Claude Boily, Sami L Gottlieb
Publikováno v:
BMJ Global Health, Vol 5, Iss 3 (2020)
IntroductionHerpes simplex virus (HSV) infection can cause painful, recurrent genital ulcer disease (GUD), which can have a substantial impact on sexual and reproductive health. HSV-related GUD is most often due to HSV type 2 (HSV-2), but may also be
Externí odkaz:
https://doaj.org/article/e64b143d3362404eb5d01f0622b40b5c
Autor:
Ifigeneia Mavranezouli, Odette Megnin-Viggars, Nick Grey, Gita Bhutani, Jonathan Leach, Caitlin Daly, Sofia Dias, Nicky J Welton, Cornelius Katona, Sharif El-Leithy, Neil Greenberg, Sarah Stockton, Stephen Pilling
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232245 (2020)
BackgroundPost-traumatic stress disorder (PTSD) is a severe and disabling condition that may lead to functional impairment and reduced productivity. Psychological interventions have been shown to be effective in its management. The objective of this
Externí odkaz:
https://doaj.org/article/6441aa78a05a467b8528031bbf05120c
Autor:
Barnaby C Reeves, Leila Rooshenas, Rhiannon C Macefield, Mark Woodward, Nicky J Welton, Benjamin R Waterhouse, Andrew D Torrance, Sean Strong, Dimitrios Siassakos, William Seligman, Chris A Rogers, Lloyd Rickard, Anne Pullyblank, Caroline Pope, Thomas D Pinkney, Samir Pathak, Anwar Owais, Jamie O’Callaghan, Stephen O’Brien, Dmitri Nepogodiev, Khaldoun Nadi, Charlotte E Murkin, Tonia Munder, Tom Milne, David Messenger, Christel M McMullan, Jonathan M Mathers, Matthew Mason, Morwena Marshall, Richard Lovegrove, Robert J Longman, Jessica Lloyd, Jeffrey Lim, Kathryn Lee, Vijay Korwar, Daniel Hughes, George Hill, Rosie Harris, Mohammed Hamdan, Hannah Gould Brown, Rachael Gooberman-Hill, James Glasbey, Caroline Fryer, Lucy Ellis, Daisy Elliott, Jo C Dumville, Tim Draycott, Jenny L Donovan, David Cotton, Joanna Coast, Madeleine Clout, Melanie J Calvert, Benjamin E Byrne, Oliver D Brown, Natalie S Blencowe, Katarzyna D Bera, Joanne Bennett, Richard Bamford, Danya Bakhbakhi, Muhammad Atif, Kate Ashton, Elizabeth Armstrong, Lazaros Andronis, Piriyankan Ananthavarathan, Jane M Blazeby
Publikováno v:
Health Technology Assessment, Vol 23, Iss 39 (2019)
Background: Surgical site infection (SSI) affects up to 20% of people with a primary closed wound after surgery. Wound dressings may reduce SSI. Objective: To assess the feasibility of a multicentre randomised controlled trial (RCT) to evaluate the e
Externí odkaz:
https://doaj.org/article/610673c18df94182a5e73e85b98411a6