Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nickolay Neznanov"'
Autor:
Nickolay Neznanov, Eugenia M Dragunsky, Konstantin M Chumakov, Lubov Neznanova, Ronald C Wek, Andrei V Gudkov, Amiya K Banerjee
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1887 (2008)
Proteasome activity is an important part of viral replication. In this study, we examined the effect of proteasome inhibitors on the replication of vesicular stomatitis virus (VSV) and poliovirus. We found that the proteasome inhibitors significantly
Externí odkaz:
https://doaj.org/article/541fbff9205c4ef2a89f5f07f3baa1b7
Autor:
Nickolay Neznanov, Andrei Gudkov
Publikováno v:
The Scientific World Journal, Vol 1, Pp 40-40 (2001)
Externí odkaz:
https://doaj.org/article/0e0ca56d382d4f3888b6fd8e4f15ccb6
Autor:
Carol Wadham, Shiloh Middlemiss, Michelle J. Henderson, Richard B. Lock, Murray D. Norris, Angelika Bongers, Katerina Gurova, Chelsea Mayoh, Mawar Karsa, Andrei V. Gudkov, Angelika Kosciolek, Michelle Haber, Ursula R. Kees, Nickolay Neznanov, Rosemary Sutton, Ali El-Ayoubi, Klaartje Somers
Publikováno v:
International Journal of Cancer. 146:1902-1916
Around 10% of acute leukemias harbor a rearrangement of the MLL/KMT2A gene, and the presence of this translocation results in a highly aggressive, therapy-resistant leukemia subtype with survival rates below 50%. There is a high unmet need to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd1aee6cd83dcda6b045fbe38b7347a
https://doi.org/10.1002/ijc.32582
https://doi.org/10.1002/ijc.32582
Autor:
Nickolay Neznanov, Andrei V. Gudkov
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 1, Pp 40-40 (2001)
The Scientific World Journal, Vol 1, Pp 40-40 (2001)
INTRODUCTION. The activation of Fas and TNF receptor by ligands stimulates fast development of apoptosis in sensitive cells. The activation of these two-death domaincontaining receptors leads to the stimulation of very similar, but not identical proa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bbe48b20267bd5fe67ea49489cf2cd
https://pubmed.ncbi.nlm.nih.gov/30147489
https://pubmed.ncbi.nlm.nih.gov/30147489
Autor:
Catherine Burkhart, Joseph J. Skitzki, Daria Fleyshman, Gary Haderski, Nickolay Neznanov, Katerina Gurova, Minhyung Kim, Chandler Wilfong, Patricia Stanhope-Baker, Andrei Purmal, Andrei V. Gudkov
Publikováno v:
Cancer research. 76(22)
Isolated limb perfusion (ILP) with the chemotherapeutic agent melphalan is an effective treatment option for extremity in-transit melanoma but is toxic and technically challenging to deliver locoregionally. CBL0137 is an experimental clinical drug wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72838778b44f256037445e4cbcc3eef6
https://pubmed.ncbi.nlm.nih.gov/27680682
https://pubmed.ncbi.nlm.nih.gov/27680682
Autor:
Amiya K. Banerjee, Lubov Neznanova, Andrei V. Gudkov, Nickolay Neznanov, Alexandru Almasan, Konstantin Chumakov
Publikováno v:
Journal of Biological Chemistry. 280:24153-24158
Activation of NF-kappaB during viral infection is one of the critical elements in innate immune response. Several virus-specific factors, such as double-stranded RNA, can trigger host defense mechanisms by inducing NF-kappaB-mediated expression of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f174861e69a0643d5e97c444bd98ebe6
https://doi.org/10.1074/jbc.m502303200
https://doi.org/10.1074/jbc.m502303200
Publikováno v:
Proceedings of the National Academy of Sciences. 101:9327-9332
Screening of expression libraries for bioactive clones that modulate the growth of mammalian cells has been limited largely to positive selections incapable of revealing growth suppressive or lethal genetic elements. We have developed a technique, se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceab88cf50e78e56b67ec2b09a439936
https://doi.org/10.1073/pnas.0403080101
https://doi.org/10.1073/pnas.0403080101
Autor:
Axel Ullrich, Andrei V. Gudkov, Nickolay Neznanov, Lubov Neznanova, Roman V. Kondratov, Donald M. O'Rourke
Publikováno v:
DNA and Cell Biology. 23:175-182
In contrast with hematopoietic cells and fibroblasts, which express mainly one form of protein tyrosine phosphatase (PTP) SHP-1 or SHP-2, epithelial cells like A431, HeLa, and 293 express both forms of PTP. These two PTP regulate NFkappaB activity di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a517dccab677d5b07a6450cd1cfdd1
https://doi.org/10.1089/104454904322964779
https://doi.org/10.1089/104454904322964779
Autor:
Kaihua Wang, Andrei V. Gudkov, Elena A. Komarova, Mikhail V. Chernov, Pavel G. Komarov, Nickolay Neznanov
Publikováno v:
Journal of Biological Chemistry. 278:15465-15468
Pifithrin alpha (PFTalpha) is a chemical compound isolated for its ability to suppress p53-mediated transactivation. It can protect cells from p53-mediated apoptosis induced by various stimuli and reduce sensitivity of mice to gamma radiation. Identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacf36b45be95c3ced367ff1cf4468b3
https://doi.org/10.1074/jbc.c300011200
https://doi.org/10.1074/jbc.c300011200
Autor:
Axel Ullrich, Donald M. O'Rourke, Nickolay Neznanov, Eugene S. Kandel, Roman V. Kondratov, Ludmila G. Burdelya, Lubov Neznanova, Andrei V. Gudkov
Publikováno v:
Journal of Biological Chemistry. 278:3809-3815
Genetic suppressor element (GSE) methodology was applied to identify new genes controlling cell response to tumor necrosis factor (TNF). A retroviral library of randomly fragmented normalized cDNA from mouse fibroblasts was screened for GSEs capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6188bdfc374ab992d603353b1518b8
https://doi.org/10.1074/jbc.m210698200
https://doi.org/10.1074/jbc.m210698200