Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nickolay Korabel"'
Autor:
Nickolay Korabel, John W. Warmenhoven, Nicholas T. Henthorn, Samuel Ingram, Sergei Fedotov, Charlotte J. Heaven, Karen J. Kirkby, Michael J. Taylor, Michael J. Merchant
Publikováno v:
Entropy, Vol 26, Iss 6, p 502 (2024)
The process of end-joining during nonhomologous repair of DNA double-strand breaks (DSBs) after radiation damage is considered. Experimental evidence has revealed that the dynamics of DSB ends exhibit subdiffusive motion rather than simple diffusion
Externí odkaz:
https://doaj.org/article/b1ffe8c2c55749f8912a4a623ebb2857
Autor:
Nickolay Korabel, Alessandro Taloni, Gianni Pagnini, Viki Allan, Sergei Fedotov, Thomas Andrew Waigh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Transport processes of many structures inside living cells display anomalous diffusion, such as endosomes in eukaryotic cells. They are also heterogeneous in space and time. Large ensembles of single particle trajectories allow the heterogen
Externí odkaz:
https://doaj.org/article/7454afbf26464077a8ec98d7b1cd710f
Autor:
Nickolay Korabel, Giuliana D. Clemente, Daniel Han, Felix Feldman, Tom H. Millard, Thomas Andrew Waigh
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-11 (2022)
Understanding how cells move is of great important for many biological processes but collective cell motion is hard to image in vivo. The authors experimentally and numerically study in vivo cell population migration during embryogenesis, quantify an
Externí odkaz:
https://doaj.org/article/d9ea2c06bb7d4b5894d1676bf01c338d
Publikováno v:
Cancer Nanotechnology, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Nanoparticles play a crucial role in nanodiagnostics, radiation therapy of cancer, and they are now widely used to effectively deliver drugs to specific sites, targeting whole organs and down to single cells, in a controlled manne
Externí odkaz:
https://doaj.org/article/753bacb225cd4fb9b04f07836063b424
Publikováno v:
Fractal and Fractional, Vol 7, Iss 10, p 758 (2023)
Transport of vesicles and organelles inside cells consists of constant-speed bidirectional movement along cytoskeletal filaments interspersed by periods of idling. This transport shows many features of anomalous diffusion. In this paper, we develop a
Externí odkaz:
https://doaj.org/article/78f8a8904b5d4036a0230f168aa94341
Autor:
Daniel Han, Nickolay Korabel, Runze Chen, Mark Johnston, Anna Gavrilova, Victoria J Allan, Sergei Fedotov, Thomas A Waigh
Publikováno v:
eLife, Vol 9 (2020)
Intracellular transport is predominantly heterogeneous in both time and space, exhibiting varying non-Brownian behavior. Characterization of this movement through averaging methods over an ensemble of trajectories or over the course of a single traje
Externí odkaz:
https://doaj.org/article/980c7e3f76b6436895aaad43ac9d0b64
Publikováno v:
Mathematics, Vol 10, Iss 3, p 375 (2022)
In this paper, we set up a stochastic model for the dynamics of active Rab5 and Rab7 proteins on the surface of endosomes and the acidification process that govern the virus–endosome fusion and endosomal escape of pH-responsive nanoparticles. We em
Externí odkaz:
https://doaj.org/article/a942bd6a3d9f4643bfad9cd933176ec3
Autor:
Nickolay Korabel, Daniel Han, Alessandro Taloni, Gianni Pagnini, Sergei Fedotov, Viki Allan, Thomas Andrew Waigh
Publikováno v:
Entropy, Vol 23, Iss 8, p 958 (2021)
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport. Some of the trajectories display switching
Externí odkaz:
https://doaj.org/article/bd3a46df520d4f80acaae47ad2475908
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207436 (2018)
Intracellular transport of organelles is fundamental to cell function and health. The mounting evidence suggests that this transport is in fact anomalous. However, the reasons for the anomaly is still under debate. We examined experimental trajectori
Externí odkaz:
https://doaj.org/article/2fe355300479413cb194a2300b4ded7b
Autor:
Daniel Han, Alessandro Taloni, Thomas A. Waigh, Gianni Pagnini, Nickolay Korabel, Sergei Fedotov, Viki Allan
Publikováno v:
Entropy
Entropy, Vol 23, Iss 958, p 958 (2021)
Volume 23
Issue 8
Korabel, N, Han, D, Taloni, A, Pagnini, G, Fedotov, S, Allan, V & Waigh, T A 2021, ' Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes ', Entropy, vol. 23, no. 8, 958 . https://doi.org/10.3390/e23080958
Entropy (Basel, Online) 23 (2021): 958-1–958-15. doi:10.3390/e23080958
info:cnr-pdr/source/autori:Korabel N.; Han D.; Taloni A.; Pagnini G.; Fedotov S.; Allan V.; Waigh T.A./titolo:Local analysis of heterogeneous intracellular transport: Slow and fast moving endosomes/doi:10.3390%2Fe23080958/rivista:Entropy (Basel, Online)/anno:2021/pagina_da:958-1/pagina_a:958-15/intervallo_pagine:958-1–958-15/volume:23
Entropy, Vol 23, Iss 958, p 958 (2021)
Volume 23
Issue 8
Korabel, N, Han, D, Taloni, A, Pagnini, G, Fedotov, S, Allan, V & Waigh, T A 2021, ' Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes ', Entropy, vol. 23, no. 8, 958 . https://doi.org/10.3390/e23080958
Entropy (Basel, Online) 23 (2021): 958-1–958-15. doi:10.3390/e23080958
info:cnr-pdr/source/autori:Korabel N.; Han D.; Taloni A.; Pagnini G.; Fedotov S.; Allan V.; Waigh T.A./titolo:Local analysis of heterogeneous intracellular transport: Slow and fast moving endosomes/doi:10.3390%2Fe23080958/rivista:Entropy (Basel, Online)/anno:2021/pagina_da:958-1/pagina_a:958-15/intervallo_pagine:958-1–958-15/volume:23
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport. Some of the trajectories display switching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc3e68c3f7c32c807696c7849d36036
http://arxiv.org/abs/2107.11553
http://arxiv.org/abs/2107.11553