Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Nickolai O Dulin"'
Autor:
Jennifer La, Eleanor Reed, Lan Chan, Larisa V Smolyaninova, Olga A Akomova, Gökhan M Mutlu, Sergei N Orlov, Nickolai O Dulin
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168363 (2016)
Transforming growth factor-beta (TGF-β) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-β signals through a complex of TGF-β receptors 1 and 2 (TGFβR1 and TGFβR2) that phosphorylate and activate S
Externí odkaz:
https://doaj.org/article/3155d7ab5546483c84f92560652057b2
Autor:
Sergei N. Orlov, Artem M. Tverskoi, Svetlana V. Sidorenko, Larisa V. Smolyaninova, Olga D. Lopina, Nickolai O. Dulin, Elizaveta A. Klimanova
Publikováno v:
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous
Externí odkaz:
https://doaj.org/article/06ca50ef462249b5824f467527df1996
Autor:
Nickolai O. Dulin
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Anoctamin-1 (ANO1), also known as TMEM16A, is the most studied member of anoctamin family of calcium-activated chloride channels with diverse cellular functions. ANO1 controls multiple cell functions including cell proliferation, survival, migration,
Externí odkaz:
https://doaj.org/article/2f417c4d1a2e46a8a35bc2b6882d38f8
Autor:
Svetlana V. Sidorenko, E. A. Klimanova, Nickolai O. Dulin, Sergei N. Orlov, Artem M. Tverskoi, Olga D. Lopina, Larisa V. Smolyaninova
Publikováno v:
Genes & Diseases
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4eb3162fc4390a48554ae4ca53d150
https://doi.org/10.1016/j.gendis.2020.01.008
https://doi.org/10.1016/j.gendis.2020.01.008
Autor:
Shehab Eid, Thomas Zerbes, Declan Williams, Xinzhu Wang, Chris Sackmann, Sammy Meier, Nickolai O Dulin, Pavel Nagorny, Gerold Schmitt-Ulms
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14823
Several strands of investigation have established that a reduction in the levels of the cellular prion protein (PrPC) is a promising avenue for the treatment of prion diseases. We recently described an indirect approach for reducing PrPC levels that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168e06bae2b44c63cd5b34f5a4555618
https://doi.org/10.3390/ijms232314823
https://doi.org/10.3390/ijms232314823
Autor:
Leah J. Witt, Robert B. Hamanaka, Angelo Y. Meliton, Gökhan M. Mutlu, E.M. O'Leary, G. Gokalp, Yufeng Tian, Nickolai O. Dulin
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 61:597-606
Idiopathic pulmonary fibrosis (IPF) is characterized by the transforming growth factor (TGF)-β-dependent differentiation of lung fibroblasts into myofibroblasts, leading to excessive deposition of extracellular matrix proteins, which distort lung ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f023e86c26d4c6c2778b98094d4de354
https://doi.org/10.1165/rcmb.2019-0008oc
https://doi.org/10.1165/rcmb.2019-0008oc
Publikováno v:
Current Medicinal Chemistry. 26:564-575
Myofibroblast activation is a critical process in the pathogenesis of tissue fibrosis accounting for 45% of all deaths. No effective therapies are available for the treatment of fibrotic diseases. We focus our mini-review on recent data showing that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9523de9a56b1330a6cf3c4a4933712
https://doi.org/10.2174/0929867324666170619105407
https://doi.org/10.2174/0929867324666170619105407
Autor:
Nickolai O. Dulin, Gabriel Barron, Fangfang Duan, Angelo Y. Meliton, Gökhan M. Mutlu, Lucia Schuger
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 60:221-231
Interstitial lung fibrosis, a frequently idiopathic and fatal disease, has been linked to the increased expression of profibrotic transforming growth factor (TGF)-βs. P311 is an RNA-binding protein that stimulates TGF-β1, -β2, and -β3 translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41440a3564f593450b2380b7e4980a40
https://doi.org/10.1165/rcmb.2018-0028oc
https://doi.org/10.1165/rcmb.2018-0028oc
Publikováno v:
B64. MECHANISTIC ADVANCES IN LUNG FIBROSIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da176bf6ca734f50bc9e4b68bf1a5f07
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4042
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4042
Publikováno v:
C57. EXTRACELLULAR MATRIX AND SUBCELLULAR DYNAMICS IN COMPLEX LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02de4dd3542a059985a24e0eb241ef93
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5537
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5537