Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Nickolai A Tchurikov"'
Autor:
Nickolai A Tchurikov, Olga V Kretova, Daria M Fedoseeva, Dmitri V Sosin, Sergei A Grachev, Marina V Serebraykova, Svetlana A Romanenko, Nadezhda V Vorobieva, Yuri V Kravatsky
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003429 (2013)
Genome instability plays a key role in multiple biological processes and diseases, including cancer. Genome-wide mapping of DNA double-strand breaks (DSBs) is important for understanding both chromosomal architecture and specific chromosomal regions
Externí odkaz:
https://doaj.org/article/f8542f42a0f54207b33b8730930a5c1d
Autor:
Nickolai A Tchurikov, Olga V Kretova
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21882 (2011)
In the Drosophila melanogaster germline, the piRNA pathway silences retrotransposons as well as other transcribed repetitive elements. Suffix is an unusual short retroelement that was identified both as an actively transcribed repetitive element and
Externí odkaz:
https://doaj.org/article/298939681d4f4622a227462bde3698e8
Autor:
Nickolai A Tchurikov, Olga V Kretova
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e476 (2007)
Separate conserved copies of suffix, a short interspersed Drosophila retroelement (SINE), and also divergent copies in the 3' untranslated regions of the three genes, have already been described. Suffix has also been identified on the 3' end of the D
Externí odkaz:
https://doaj.org/article/164cae8d66ea44018d1b9631b03637b5
Autor:
Kravatsky, Nickolai A. Tchurikov, Elena S. Klushevskaya, Ildar R. Alembekov, Antonina N. Kretova, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9842
The expression of clusters of rDNA genes influences pluripotency; however, the underlying mechanisms are not yet known. These clusters shape inter-chromosomal contacts with numerous genes controlling differentiation in human and Drosophila cells. Thi
Publikováno v:
Biology; Volume 11; Issue 10; Pages: 1422
In this paper, we describe a method for the study of colocalization effects between stretch–stretch and stretch–point genome tracks based on a set of indices varying within the (–1, +1) interval. The indices combine the distances between the ce
Autor:
Nickolai A. Tchurikov, G.I. Kravatskaya, Y. V. Kravatsky, E. S. Klushevskaya, D. M. Fedoseeva
Publikováno v:
Doklady Biochemistry and Biophysics. 496:22-26
To study the rDNA contacts with genes in three human cell lines of different origin, we used 4C approach. Our data indicate that the same set of about five hundred genes frequently shape contacts with rDNA clusters in HEK293T, K652, and hESM01 cells.
Autor:
Nickolai A. Tchurikov, Ildar R. Alembekov, Elena S. Klushevskaya, Antonina N. Kretova, Ann M. Keremet, Anastasia E. Sidorova, Polina B. Meilakh, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7201
Double-strand DNA breakes (DSBs) are the most deleterious and widespread examples of DNA damage. They inevitably originate from endogenous mechanisms in the course of transcription, replication, and recombination, as well as from different exogenous
Autor:
Ildar R. Alembekov, Olga V. Kretova, Nickolai A. Tchurikov, Y. V. Kravatsky, I Y Slovohotov, D. M. Fedoseeva, E. S. Klushevskaya
Publikováno v:
Молекулярная биология. 54:262-266
rDNA genes play an important role in epigenetic regulation and in differentiation of eukaryotic cells. Using the 4C (circular chromosome conformation capture) approach and model HEK293T cells, we analyzed the rDNA-contacting gene FANK1, using anchor
Autor:
I Y Slovohotov, Nickolai A. Tchurikov, Olga V. Kretova, Y. V. Kravatsky, D. M. Fedoseeva, E. S. Klushevskaya
Publikováno v:
Молекулярная биология. 54:445-449
In experiments on mouse and human cells it was demonstrated that rDNA plays an important role in epigenetic regulation of many genes. To identify and study rDNA-contacting genes in Drosophila we used the 4С (circular chromosome conformation capture)
Autor:
D. M. Fedoseeva, Y. V. Kravatsky, Olga V. Kretova, E. S. Klushevskaya, Nickolai A. Tchurikov, G.I. Kravatskaya
Publikováno v:
Doklady Biochemistry and Biophysics. 490:50-53
In order to study the effects of heat shock treatment on the distribution of rDNA contacts at the region possessing DUX genes inside chromosome 4 we used 4C approach. Our data indicate that the treatment removes the frequent rDNA contacts in this reg