Effects of Extended Cage Component Sanitation Interval on the Microenvironment, Health, and Gastrointestinal Microbiome of Rats ( Rattus norvegicus ).

Autor: Taylor JZ; Office of Laboratory Animal Resources, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado., Fong DL, Habenicht LM; Office of Laboratory Animal Resources, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado., Fink MK; Office of Laboratory Animal Resources, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado., Leszczynski JK; Office of Laboratory Animal Resources, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado., Frank DN; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Kofonow JM; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Robertson CE; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Nicklawsky AG; University of Colorado Cancer Center Biostatistics Core, Aurora, Colorado., Schurr MJ; Department of Immunology and Microbiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado., Manuel CA; Office of Laboratory Animal Resources, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado.

Publikováno v: Journal of the American Association for Laboratory Animal Science : JAALAS [J Am Assoc Lab Anim Sci] 2023 May 01; Vol. 62 (3), pp. 212-221. Date of Electronic Publication: 2023 Apr 18.

Differential responses to immune checkpoint inhibitor dictated by pre-existing differential immune profiles in squamous cell carcinomas caused by same initial oncogenic drivers.

Autor: Chen SMY; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA.; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Popolizio V; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Woolaver RA; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Ge H; UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Krinsky AL; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., John J; UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Danis E; Department of Pharmacology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Ke Y; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Kramer Y; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA.; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Bian L; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Nicklawsky AG; Department of Pediatrics and Department of Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Gao D; Department of Pediatrics and Department of Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA., Liu S; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Chen Z; UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Wang XJ; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA. xj.wang@cuanschutz.edu., Wang JH; UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA. JHW51@pitt.edu.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Apr 02; Vol. 41 (1), pp. 123. Date of Electronic Publication: 2022 Apr 02.

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts.

Autor: Woolaver RA; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Wang X; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Krinsky AL; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Waschke BC; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Chen SMY; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Popolizio V; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Nicklawsky AG; Pediatrics, Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Gao D; Pediatrics, Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Chen Z; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Jimeno A; Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Wang XJ; Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Wang JH; Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA jing.wang@CUanschutz.edu.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Jan; Vol. 9 (1).

Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15 ⁺ Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma.

Autor: Chen SMY; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Li B; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Nicklawsky AG; Department of Pediatrics, Department of Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Krinsky AL; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Brunetti T; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Woolaver RA; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Wang X; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Chen Z; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Young CD; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Gao D; Department of Pediatrics, Department of Biostatistics and Informatics, Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA., Wang XJ; Department of Pathology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA.; Veterans Affairs Medical Center, VA Eastern Colorado Health Care System, Aurora, CO 80045, USA., Wang JH; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO 80045, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 09; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 09.