Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicklaus A. Sparrow"'
Autor:
Gena Guidry, Nicklaus A. Sparrow, Hyyat S. Marshall, Roberta De Souza Santos, Suman P. Bharath, Michael M. Gezalian, Margareta D. Pisarska, Jean-Philippe Vit, Scott A. Kelly, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Urinary tract infections (UTIs) are common and frequently precipitate delirium-like states. Advanced age coincident with the postmenopausal period is a risk factor for delirium following UTIs. We previously demonstrated a pathological role f
Externí odkaz:
https://doaj.org/article/757169c0da244f42bd6bf2223a53515d
Autor:
Faizan Anwar, Nicklaus A. Sparrow, Mohammad Harun Rashid, Gena Guidry, Michael M. Gezalian, Eric J. Ley, Maya Koronyo-Hamaoui, Itai Danovitch, E. Wesley Ely, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Acute neuropsychiatric impairments occur in over 70% of patients with acute lung injury. Mechanical ventilation is a well-known precipitant of acute lung injury and is strongly associated with the development of acute delirium and anxiety ph
Externí odkaz:
https://doaj.org/article/5b0cf2ca25d24b3cb45f3271401af387
Autor:
Mohammad Harun Rashid, Nicklaus A. Sparrow, Faizan Anwar, Gena Guidry, Ambart E. Covarrubias, Haoming Pang, Chandrakumar Bogguri, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The
Externí odkaz:
https://doaj.org/article/27295915fdbf4affa8700bfa43899cca
Autor:
Nicklaus A. Sparrow, Gena Guidry, Faizan Anwar, Sonja Darwish, Scott A. Kelly, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Prone positioning is an established treatment for severe acute lung injury conditions. Neuronal dysfunction frequently occurs with mechanical ventilation-induced acute lung injury (VILI) and clinically manifests as delirium. We previously reported a
Externí odkaz:
https://doaj.org/article/4e5d64dc193f46ca9b953edd23f804ca
Autor:
Shouri Lahiri, Padmesh S. Rajput, Konrad Schlick, Nicklaus A. Sparrow, Michael M Gezalian, Luigi Mangiacotti
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Adrenoceptor and calcium channel modulating medications are widely used in clinical practice for acute neurological and systemic conditions. It is generally assumed that the cerebrovascular effects of these drugs mirror that of their systemic effects
Autor:
Shouri Lahiri, S. Ananth Karumanchi, Gena Guidry, Faizan Anwar, Chandrakumar Bogguri, Mohammad H. Rashid, Haoming Pang, Nicklaus A. Sparrow, Ambart E. Covarrubias
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
BackgroundUrinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The pathogene
Autor:
Padmesh S. Rajput, Maranatha Ayodele, Peyton L. Nisson, Faizan Anwar, Michael M Gezalian, Shouri Lahiri, Mohammad H. Rashid, Shahed Toossi, Nicklaus A. Sparrow, S. Ananth Karumanchi, Ambart E. Covarrubias, E. Wesley Ely
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Am J Respir Cell Mol Biol
Am J Respir Cell Mol Biol
Mechanical ventilation is a known risk factor for delirium, a cognitive impairment characterized by dysfunction of the frontal cortex and hippocampus. Although IL-6 is upregulated in mechanical ventilation–induced lung injury (VILI) and may contrib
Autor:
Oliver Valdivia Camacho, Stephani Klingeman Plati, Nicklaus A. Sparrow, Matthias A. Karajannis, Marisa A. Fuse, Jeanine Pestoni, Cristina Fernandez-Valle, Maria O. Onatunde, Maria Clara Franco
Publikováno v:
The Journal of Biological Chemistry
Neurofibromatosis type 2 (NF2) is an autosomal-dominant disorder characterized by the development of bilateral vestibular schwannomas. The NF2 gene encodes the tumor suppressor merlin, and loss of merlin activity promotes tumorigenesis and causes NF2
Autor:
Luigi Mangiacotti, Yosef Koronyo, Padmesh S. Rajput, Maya Koronyo-Hamaoui, Michael M Gezalian, Shouri Lahiri, Nicklaus A. Sparrow
Background: Prior published data show that short-term mechanical ventilation contributes to pathological hallmarks of Alzheimer’s Disease (AD) by increasing cerebral accumulation of the amyloid-β1-40 (Aβ1-40) peptide and neuroinflammation while u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c6dcc9d720ae88fac9232c00a3d8779
https://doi.org/10.21203/rs.3.rs-52225/v1
https://doi.org/10.21203/rs.3.rs-52225/v1
Autor:
Marisa A. Fuse, Cristina Fernandez-Valle, Stephani Klingeman Plati, Nicklaus A. Sparrow, Maria Clara Franco, Maria O. Onatunde
Publikováno v:
Free Radical Biology and Medicine. 112:86-87
Production of peroxynitrite and formation of nitrotyrosine, implicated in cell death in neurodegeneration and inflammatory conditions, is also found in multiple tumors. Paradoxically, whether tyrosine nitration plays a role in tumor cell survival is