Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicklas W. C. Garrelfs"'
Autor:
Dieter Henrik Heiland, Vidhya M. Ravi, Simon P. Behringer, Jan Hendrik Frenking, Julian Wurm, Kevin Joseph, Nicklas W. C. Garrelfs, Jakob Strähle, Sabrina Heynckes, Jürgen Grauvogel, Pamela Franco, Irina Mader, Matthias Schneider, Anna-Laura Potthoff, Daniel Delev, Ulrich G. Hofmann, Christian Fung, Jürgen Beck, Roman Sankowski, Marco Prinz, Oliver Schnell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Astrocytes play important roles in neuroinflammatory diseases. Here the authors characterize human glioblastoma-associated astrocytes by gene expression and demonstrate their immunosuppressive role promoted by interactions with tumor and microglia ce
Externí odkaz:
https://doaj.org/article/bda58627bc774fe381635dc078c37616
Publikováno v:
Molecular Neurobiology. 56:6046-6055
Glioblastoma multiforme (GBM) is the most aggressive brain tumor with a high recurrence rate and a median survival of about 16 months even with multimodal therapy. Novel experimental strategies against malignant gliomas include cyclooxygenase (COX) i
Autor:
Mukesch Shah, Daniel Delev, Oliver Schnell, Marie Follo, Ulrich G. Hofmann, Melanie Meyer-Luehmann, Kevin Joseph, Julian Wurm, Yashar Naseri, Paolo d'Errico, Pamela Franco, Vidhya M Ravi, Simon P Behringer, Roman Sankowski, Nicklas W C Garrelfs, Irina Mader, Jürgen Beck, Dieter Henrik Heiland
Publikováno v:
Life Science Alliance
Life science alliance 2(4), e201900305 (2019). doi:10.26508/lsa.201900305
Life science alliance 2(4), e201900305 (2019). doi:10.26508/lsa.201900305
Therapeutically resected, adult brain segments were maintained and characterized for an extended period to study glioblastoma progression and treatment in its almost natural environment.
When it comes to the human brain, models that closely mimi
When it comes to the human brain, models that closely mimi
Autor:
Jessica, Guenzle, Louisa J, Wolf, Nicklas W C, Garrelfs, Jonathan M, Goeldner, Nadja, Osterberg, Cora R, Schindler, Joseph E, Saavedra, Astrid, Weyerbrock
Publikováno v:
Cell Death Discovery
Glioblastoma is associated with poor survival and a high recurrence rate in patients due to inevitable uncontrolled infiltrative tumor growth. The elucidation of the molecular mechanisms may offer opportunities to prevent relapses. In this study we i