Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Nicklas Raun, Jacobsen"'
Autor:
Fiona Murphy, Nicklas Raun Jacobsen, Emilio Di Ianni, Helinor Johnston, Hedwig Braakhuis, Willie Peijnenburg, Agnes Oomen, Teresa Fernandes, Vicki Stone
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-23 (2022)
Abstract Background The EU-project GRACIOUS developed an Integrated Approach to Testing and Assessment (IATA) to support grouping high aspect ratio nanomaterials (HARNs) presenting a similar inhalation hazard. Application of grouping reduces the need
Externí odkaz:
https://doaj.org/article/59e92a528c884918aafe1f0893c6e878
Autor:
Emilio Di Ianni, Johanna Samulin Erdem, Peter Møller, Nicklas Mønster Sahlgren, Sarah Søs Poulsen, Kristina Bram Knudsen, Shan Zienolddiny, Anne Thoustrup Saber, Håkan Wallin, Ulla Vogel, Nicklas Raun Jacobsen
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Multi-walled carbon nanotubes (MWCNT) have received attention due to extraordinary properties, resulting in concerns for occupational health and safety. Costs and ethical concerns of animal testing drive a need for in vitro models
Externí odkaz:
https://doaj.org/article/0d6a87d0ebdf4881add32020731523b6
Autor:
Shihori Tanabe, Jason O’Brien, Knut Erik Tollefsen, Youngjun Kim, Vinita Chauhan, Carole Yauk, Elizabeth Huliganga, Ruthann A. Rudel, Jennifer E. Kay, Jessica S. Helm, Danielle Beaton, Julija Filipovska, Iva Sovadinova, Natalia Garcia-Reyero, Angela Mally, Sarah Søs Poulsen, Nathalie Delrue, Ellen Fritsche, Karsta Luettich, Cinzia La Rocca, Hasmik Yepiskoposyan, Jördis Klose, Pernille Høgh Danielsen, Maranda Esterhuizen, Nicklas Raun Jacobsen, Ulla Vogel, Timothy W. Gant, Ian Choi, Rex FitzGerald
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result of natural cellular processes, intracellular signaling, or as adverse responses associated with diseases or exposure to oxidizing chemical and non-chemical stres
Externí odkaz:
https://doaj.org/article/6e4603ffc4664fc2936ec3f4a2a4f907
Autor:
Katja Maria Bendtsen, Louise Gren, Vilhelm Berg Malmborg, Pravesh Chandra Shukla, Martin Tunér, Yona J. Essig, Annette M. Krais, Per Axel Clausen, Trine Berthing, Katrin Loeschner, Nicklas Raun Jacobsen, Henrik Wolff, Joakim Pagels, Ulla Birgitte Vogel
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-25 (2020)
Abstract Background Diesel exhaust is carcinogenic and exposure to diesel particles cause health effects. We investigated the toxicity of diesel exhaust particles designed to have varying physicochemical properties in order to attribute health effect
Externí odkaz:
https://doaj.org/article/8cf50370daf748e79c4cb46d6e75619d
Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice
Autor:
Justyna Modrzynska, Trine Berthing, Gitte Ravn-Haren, Nicklas Raun Jacobsen, Ingrid Konow Weydahl, Katrin Loeschner, Alicja Mortensen, Anne Thoustrup Saber, Ulla Vogel
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Background Little is known about the mechanism underlying the genotoxicity observed in the liver following pulmonary exposure to carbon black (CB) nanoparticles (NPs). The genotoxicity could be caused by the presence of translocated particle
Externí odkaz:
https://doaj.org/article/a64a816c979a4ee1923e8a3e3952af7f
Autor:
Aneta Wierzbicka, Yuliya Omelekhina, Anne Thoustrup Saber, Erica Bloom, Louise Gren, Sarah Søs Poulsen, Bo Strandberg, Joakim Pagels, Nicklas Raun Jacobsen
Publikováno v:
Indoor Air. 32
Autor:
Aneta, Wierzbicka, Yuliya, Omelekhina, Anne Thoustrup, Saber, Erica, Bloom, Louise, Gren, Sarah Søs, Poulsen, Bo, Strandberg, Joakim, Pagels, Nicklas Raun, Jacobsen
Publikováno v:
Indoor airREFERENCES. 32(12)
We spend most of our time indoors; however, little is known about the effects of exposure to aerosol particles indoors. We aimed to determine differences in relative toxicity and physicochemical properties of PM
Publikováno v:
Drug and Chemical Toxicology. 45:2388-2397
Some implantable medical devices contain silver. We aimed to assess at what amount implanted silver becomes toxic. Silver was elevated in bodily fluids and tissues surrounding silver-containing implants. Silver released from implants also distributes
Autor:
Emilio, Di Ianni, Peter, Møller, Tanya, Cholakova, Henrik, Wolff, Nicklas Raun, Jacobsen, Ulla, Vogel
Publikováno v:
Nanotoxicology. 16(4)
Carbon black nanoparticles (CBNPs) have a large surface area/volume ratio and are known to generate oxidative stress and inflammation that may result in genotoxicity and cancer. Here, we evaluated the primary and inflammatory response-driven (i.e. se
Publikováno v:
Toxicological Sciences. 183:184-194
Carbon nanotubes (CNTs) are speculated to cause mesothelioma by persistent inflammation, oxidative stress, tissue injury, and genotoxicity. To investigate the pleural response to CNTs, we exposed C57BL/6 mice by intrapleural injection of 0.2 or 5 µg