Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicklas Fiedler"'
Autor:
Chunjiang Wei, Ziwen Gao, Robert Mau, Thomas Eickner, Gabor Jüttner, Nicklas Fiedler, Hermann Seitz, Thomas Lenarz, Verena Scheper
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1236 (2024)
Background: Preserving residual hearing after cochlear implant (CI) surgery remains a crucial challenge. The application of dexamethasone (DEX) has been proven to positively affect residual hearing. To deliver DEX in a localized and controlled way, a
Externí odkaz:
https://doaj.org/article/24b2a0c72864451592ed7825fd6345b6
Autor:
Stefan Oschatz, Selina Schultz, Nicklas Fiedler, Volkmar Senz, Klaus-Peter Schmitz, Niels Grabow, Daniela Koper
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26268- (2024)
Minimally invasive surgery procedures are of utmost relevance in clinical practice. However, the associated mechanical stress on the material poses a challenge for new implant developments. In particular PLLA, one of the most widely used polymeric bi
Externí odkaz:
https://doaj.org/article/cce706724d7847f4b51a88146859f523
Autor:
Robert Mau, Thomas Eickner, Gábor Jüttner, Ziwen Gao, Chunjiang Wei, Nicklas Fiedler, Volkmar Senz, Thomas Lenarz, Niels Grabow, Verena Scheper, Hermann Seitz
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1584 (2023)
A novel approach for the long-term medical treatment of the inner ear is the diffusion of drugs through the round window membrane from a patient-individualized, drug-eluting implant, which is inserted in the middle ear. In this study, drug-loaded (10
Externí odkaz:
https://doaj.org/article/5be2ca9a943b493db94e194655b5b954
Autor:
Dana Dohr, Nicklas Fiedler, Wolfram Schmidt, Niels Grabow, Robert Mlynski, Sebastian P. Schraven
Publikováno v:
Applied Sciences, Vol 11, Iss 11, p 5162 (2021)
Background: During cochlear implantation, the electrode array has significant friction with the sensitive endocochlear lining and causes mutual mechanical trauma while the array is being inserted. Both, the impact of insertion speed on electrode fric
Externí odkaz:
https://doaj.org/article/b17d8ea8648f4da6b83f0f7450c25bf3
Publikováno v:
Current Directions in Biomedical Engineering. 8:368-371
The characterization of mechanical properties of materials used in biomedical applications is essential for performance evaluation. In addition to quasi-static tests, dynamic tests extend the range of methods and allow predictions of failure, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22d4844e4e368aa608763aea45f0ade
https://doi.org/10.1515/cdbme-2022-1094
https://doi.org/10.1515/cdbme-2022-1094
Publikováno v:
Current Directions in Biomedical Engineering. 8:356-359
In this study, DSC experiments were used to elaborate an annealing protocol for injection molded very high molecular weight (VHMW) PLLA with two molecular masses, 320,000 g/mol and 700,000 g/mol. The initial material obtained from the injection moldi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b674a317a1dbe705d26281ad02483edf
https://doi.org/10.1515/cdbme-2022-1091
https://doi.org/10.1515/cdbme-2022-1091
Publikováno v:
Current Directions in Biomedical Engineering. 8:470-473
To simulate the specific material properties of thermoplastic polymers a suitable constitutive model is essential. The parallel rheological framework (PRF) model was calibrated and evaluated in this study as potential constitutive model for polymer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d507cfcb236a9b395ddf417ab7a3b92
https://doi.org/10.1515/cdbme-2022-1120
https://doi.org/10.1515/cdbme-2022-1120
Publikováno v:
Current Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 189-192 (2020)
Electrospinning is a popular method for creating nonwoven fiber materials for a wide variety of applications. In the field of biomaterials, electrospun materials are favoured because of a high surface-to-volume ratio which can be useful for drug load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4138c8973eac8c2c4c770f475a6fb9d3
https://doaj.org/article/02d3ef70920248408744db0828e7d3cf
https://doaj.org/article/02d3ef70920248408744db0828e7d3cf
Publikováno v:
Current Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 185-188 (2020)
The development and advancement of polymeric implant materials is a frequent focus in current research. The combination of polymeric materials with diverging properties provides a wide range of new materials with innovative characteristics. One techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c016804bda9e62b408eb2f5e0ca71992
https://doi.org/10.1515/cdbme-2020-3047
https://doi.org/10.1515/cdbme-2020-3047
Autor:
N. Grabow, Katharina Riedel, Dalibor Bajer, Stefanie Kohse, Thomas Eickner, V. Pauker, Daniela Arbeiter, K.-P. Schmitz, Nicklas Fiedler, Michael Stiehm, Katharina Wulf
Publikováno v:
Biomedical Engineering / Biomedizinische Technik. 64:19-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0bd4d0e5dc8984009d969c0e0e9669
https://doi.org/10.1515/bmt-2019-7002
https://doi.org/10.1515/bmt-2019-7002