Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nickie L. Seto"'
Autor:
Yudong Liu, Carmelo Carmona-Rivera, Erica Moore, Nickie L. Seto, Jason S. Knight, Milton Pryor, Zhi-Hong Yang, Saskia Hemmers, Alan T. Remaley, Kerri A. Mowen, Mariana J. Kaplan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Increasing evidence suggests that neutrophil extracellular traps (NETs) may play a role in promoting atherosclerotic plaque lesions in humans and in murine models. The exact pathways involved in NET-driven atherogenesis remain to be systematically ch
Externí odkaz:
https://doaj.org/article/b81039b365404496821615bd0246821e
Autor:
Yaíma L. Lightfoot, Saeko Nakajima, Verena M. Link, Samira Tamoutounour, Oliver J. Harrison, Christopher K. E. Bleck, Mariana J. Kaplan, E. Merrill, Jonathan L. Linehan, Margery G. Smelkinson, Seong-Ji Han, Yasmine Belkaid, C. Hurabielle, Nicolas Bouladoux, Nickie L Seto, Michail S. Lionakis
Publikováno v:
Proc Natl Acad Sci U S A
Under steady-state conditions, the immune system is poised to sense and respond to the microbiota. As such, immunity to the microbiota, including T cell responses, is expected to precede any inflammatory trigger. How this pool of preformed microbiota
Autor:
Marie L. Feser, Heather M. Rothfuss, Yuko Okamoto, Brian D. Cherrington, Ashley Visser, William J. Janssen, Valerie Minarchick, Timothy M. Wilson, Stacey M. Thomas, Ashley Frazer-Abel, Kevin D. Deane, Jill M. Norris, Stephanie Devoe, V. Michael Holers, Nickie L Seto, M. Kristen Demoruelle, Michael P. Mohning, Justin August, Mariana J. Kaplan, Jaron Arbet, Miranda E. Kroehl, Laura Lenis Charry, Chelsie Fleischer
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 74(1)
OBJECTIVE Mechanisms leading to anti-citrullinated protein antibody (ACPA) generation in rheumatoid arthritis (RA) are hypothesized to originate in the lung. We undertook this study to understand associations between neutrophil extracellular trap (NE
Autor:
Dominic Sinibaldi, Nehal N. Mehta, G. Illei, Mariana J. Kaplan, Binbing Yu, Xinghao Wang, Philip M. Carlucci, L. Wang, Kerry A. Casey, Martin P. Playford, Shiliang Wang, Wendy I. White, Nickie L Seto, Michael A Smith, Alan T. Remaley
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)References. 73(3)
OBJECTIVE Neutrophil dysregulation and the type I interferon (IFN) axis have been proposed to contribute to premature cardiovascular disease, a leading cause of mortality in patients with systemic lupus erythematosus (SLE). In the present study, we e
Autor:
Luz P. Blanco, Victoria Hoffmann, Carmelo Carmona-Rivera, Peter S.T. Yuen, Hege Lynum Pedersen, Nickie L Seto, Yaíma L. Lightfoot, Xinghao Wang, Zu Xi Yu, Mariana J. Kaplan
Publikováno v:
Arthritis Rheumatol
OBJECTIVE A role for mitochondrial dysfunction has been proposed in the immune dysregulation and organ damage characteristic of systemic lupus erythematosus (SLE). Idebenone is a coenzyme Q10 synthetic quinone analog and an antioxidant that has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88412c57844236ef9157d7e0769a9766
https://europepmc.org/articles/PMC7050361/
https://europepmc.org/articles/PMC7050361/
Autor:
V. Michael Holers, William H. Robinson, Michael H. Weisman, Emily Bowers, M. Kristen Demoruelle, Nickie L Seto, Lauren J. Lahey, Jill M. Norris, Jeremy Sokolove, Mariana J. Kaplan, Monica M. Purmalek, Kevin D. Deane
Publikováno v:
Arthritis & Rheumatology. 70:516-527
Objective The location and mechanisms involved in the initial generation of autoantibodies to citrullinated and noncitrullinated proteins/peptides during the natural history of rheumatoid arthritis (RA) development is incompletely understood. This st
Autor:
Katherine Pak, José J. Torres-Ruíz, Diana Gómez-Martín, Iago Pinal-Fernandez, José C. Milisenda, Frederick W. Miller, Yuji Hosono, Nickie L Seto, Olivier Benveniste, Adam I. Schiffenbauer, Lisa Christopher-Stine, Lisa G. Rider, Alexander M. Gorbach, Josep M. Grau-Junyent, Prateek Gowda, Ingrid E. Lundberg, Cátia Fernandes-Cerqueira, Monica M. Purmalek, Albert Selva-O'Callaghan, J. Michelle Kahlenberg, Nathan Arnett, Mariana J. Kaplan, Andrew L. Mammen, Carmelo Carmona-Rivera
Publikováno v:
JCI insight. 5(3)
Idiopathic inflammatory myopathies (IIM) are characterized by muscle inflammation and weakness, myositis-specific autoantibodies (MSAs), and extramuscular organ damage. The role of neutrophil dysregulation and neutrophil extracellular traps (NETs) in
Autor:
Yudong Liu, Mariana J. Kaplan, Victoria Hoffman, Luz P. Blanco, Nickie L Seto, Hege Lynum Pedersen, Yaíma L. Lightfoot, Peter S.T. Yuen, Carmelo Carmona-Rivera
Publikováno v:
Abstracts.
Background Immune dysregulation and organ damage are characteristic of systemic lupus erythematosus (SLE). We previously reported that mitochondrial reactive oxygen species (ROS) and the release of oxidized mitochondrial DNA (mtDNA) may be involved i
Publikováno v:
Ecological Research. 31:617-626
Japanese giant flying squirrels, Petaurista leucogenys, are entirely arboreal folivores. From spring to summer, their principal food source consists of leaves of the deciduous oak Quercus acutissima in western Tokyo, Japan. Before consuming the centr
Autor:
Rishi R. Goel, Paul R. Thompson, Yaíma L. Lightfoot, Hong-Wei Sun, Yudong Liu, Scott A. Coonrod, Erica Moore, Pragnesh Mistry, Santanu Mondal, Padmavathy Nandha Premnath, Nickie L Seto, Liam J. O’Neil, Kan Jiang, Stefania Dell'Orso, Carmelo Carmona-Rivera, Katherine Gribbons, Victoria Hoffmann, Mariana J. Kaplan
The peptidylarginine deiminases PAD2 and PAD4 are implicated in the pathogenesis of several autoimmune diseases. PAD4 may be pathogenic in systemic lupus erythematosus (SLE) through its role in neutrophil extracellular trap (NET) formation that promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d95abeb0d2f62d76402a5728bf77136
https://europepmc.org/articles/PMC6328098/
https://europepmc.org/articles/PMC6328098/