Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nickie C Chan"'
Autor:
Nickie C. Chan, David C. Chan, Willem den Besten, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies
Publikováno v:
Journal of Biological Chemistry. 289:19789-19798
Because the deubiquitinating enzyme USP33 is involved in several important cellular processes (β-adrenergic receptor recycling, centrosome amplification, RalB signaling, and cancer cell migration), its levels must be carefully regulated. Using quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31d6262b621058df6e3778c02c27d33
https://doi.org/10.1074/jbc.m114.569392
https://doi.org/10.1074/jbc.m114.569392
Autor:
Natalie J. Kolawa, David C. Chan, Anna M. Salazar, Michael J. Sweredoski, Robert Graham, Nickie C. Chan, Anh H. Pham, Sonja Hess
Publikováno v:
Human Molecular Genetics
Parkin, an E3 ubiquitin ligase implicated in Parkinson's disease, promotes degradation of dysfunctional mitochondria by autophagy. Using proteomic and cellular approaches, we show that upon translocation to mitochondria, Parkin activates the ubiquiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b3564a1fbd87be175562091b5ccd5d
http://europepmc.org/articles/PMC3071670
http://europepmc.org/articles/PMC3071670
Autor:
Terrence D. Mulhern, Trevor Lithgow, Carole Jabbour, Vladimir A Likic, Nemin Celik, Nickie C Chan, Ross F. Waller
Publikováno v:
Eukaryotic Cell. 8:19-26
Microsporidia are a group of highly adapted obligate intracellular parasites that are now recognized as close relatives of fungi. Their adaptation to parasitism has resulted in broad and severe reduction at (i) a genomic level by extensive gene loss,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a114ea7abbea8e828779c656185114da
https://doi.org/10.1128/ec.00313-08
https://doi.org/10.1128/ec.00313-08
Autor:
Andrew J. Perry, Vladimir A Likic, Franziska B Lueder, Nickie C Chan, P. Peter Wolynec, Trevor Lithgow, Joanne M Hulett, Paul R. Gooley
Publikováno v:
Monash University
Mitochondria cannot be made de novo. Mitochondrial biogenesis requires that up to 1000 proteins are imported into mitochondria, and the protein import pathway relies on hetero-oligomeric translocase complexes in both the inner and outer mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b83124763be2e5d9485cca438714ba8
https://doi.org/10.1016/j.jmb.2007.12.021
https://doi.org/10.1016/j.jmb.2007.12.021
Autor:
Lena Burri, David I Stapleton, Lynn Ramage, Ian E Gentle, Katherine Vascotto, Nickie C Chan, Trevor Lithgow, Traude H. Beilharz
Publikováno v:
Monash University
Mitochondria evolved from a bacterial endosymbiont ancestor in which the integral outer membrane proteins would have been beta-barrel structured within the plane of the membrane. Initial proteomics on the outer membrane from yeast mitochondria sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc9f76b3c0efe38918fd17b806157d8
https://doi.org/10.1111/j.1742-4658.2006.05171.x
https://doi.org/10.1111/j.1742-4658.2006.05171.x
Publikováno v:
The Journal of Biological Chemistry
Background: Mdv1 and Fis1 are components of the yeast mitochondrial fission complex. Results: In the dimeric Mdv1-Fis1 crystal structure, the Mdv1 coiled coil mediates two protein interactions important for mitochondrial fission. Conclusion: The Mdv1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5946b177d0f0d8fa54e878afec9f1f3e
https://resolver.caltech.edu/CaltechAUTHORS:20120501-070603033
https://resolver.caltech.edu/CaltechAUTHORS:20120501-070603033
Autor:
Trevor Lithgow, Nickie C Chan
Publikováno v:
Monash University
The sorting and assembly machinery (SAM) complex functions in the assembly of β-barrel proteins into the mitochondrial outer membrane. It is related to the Omp85/YaeT machinery in bacterial outer membranes, but the eukaryotic SAM complex is distingu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e596517791d28b79dbd7a7ddeb87084
https://europepmc.org/articles/PMC2174179/
https://europepmc.org/articles/PMC2174179/
Autor:
Mary-Jane Gething, William P. Tansey, Bhupinder Pal, Leon Helfenbaum, Kaeling Tan, Nickie C Chan
Publikováno v:
Molecular biology of the cell. 18(2)
The Saccharomyces cerevisiae basic leucine zipper transcription factor Hac1p is synthesized in response to the accumulation of unfolded polypeptides in the lumen of the endoplasmic reticulum (ER), and it is responsible for up-regulation of ∼5% of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce254a82aac83cb7d1c97848166b953b
https://pubmed.ncbi.nlm.nih.gov/17108329
https://pubmed.ncbi.nlm.nih.gov/17108329
Publikováno v:
Monash University
In fungi and animals the translocase in the outer mitochondrial membrane (TOM complex) consists of multiple components including the receptor subunit Tom70. Genome sequence analyses suggest no Tom70 receptor subunit exists in plants or protozoans, ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297fd7098f7e2973358f47f369a6f8dd
https://pubmed.ncbi.nlm.nih.gov/16566938
https://pubmed.ncbi.nlm.nih.gov/16566938
Autor:
David C. Chan, Nickie C. Chan
Publikováno v:
Autophagy. 7:771-772
Parkin is a ubiquitin E3 ligase that is implicated in familial Parkinson disease (PD). Previous studies have established its role in mitophagy, a pathway whereby dysfunctional mitochondria are targeted for autophagic degradation. We recently reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590c1ef52ec92c285e0b9e4324a36851
https://doi.org/10.4161/auto.7.7.15453
https://doi.org/10.4161/auto.7.7.15453