Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicki Konstantakopoulos"'
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 377 (2020)
The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N. atra venom, as well as examining the efficacy of three Chinese monovalent antiv
Externí odkaz:
https://doaj.org/article/65eb8269e69042f684ccb261ead44079
Autor:
Steven Fernandez, Wayne Hodgson, Janeyuth Chaisakul, Rachelle Kornhauser, Nicki Konstantakopoulos, Alexander Ian Smith, Sanjaya Kuruppu
Publikováno v:
Toxins, Vol 6, Iss 5, Pp 1586-1597 (2014)
This study investigated the in vitro toxic effects of Bitis arietans venom and the ability of antivenom produced by the South African Institute of Medical Research (SAIMR) to neutralize these effects. The venom (50 µg/mL) reduced nerve-mediated twit
Externí odkaz:
https://doaj.org/article/3df292f7e51e42b89c8269fe44da9339
Publikováno v:
Journal of Toxins. 2015:1-7
In Sudan, as in many African countries, no local specific antivenom is manufactured resulting in snake bite victims being treated by antivenoms imported from abroad. In the present work we measured the cytotoxic effect of the recently described spitt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79ad6252ec12d213d6d3c00b999b2ed6
https://doi.org/10.1155/2015/167492
https://doi.org/10.1155/2015/167492
Autor:
Rachelle Kornhauser, Steven Fernandez, Alexander Ian Smith, Sanjaya Kuruppu, Wayne C. Hodgson, Janeyuth Chaisakul, Nicki Konstantakopoulos
Publikováno v:
Toxins, Vol 6, Iss 5, Pp 1586-1597 (2014)
Toxins; Volume 6; Issue 5; Pages: 1586-1597
Toxins
Toxins; Volume 6; Issue 5; Pages: 1586-1597
Toxins
This study investigated the in vitro toxic effects of Bitis arietans venom and the ability of antivenom produced by the South African Institute of Medical Research (SAIMR) to neutralize these effects. The venom (50 µg/mL) reduced nerve-mediated twit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0913a736ce7b73314c2d61024b088095
http://www.mdpi.com/2072-6651/6/5/1586
http://www.mdpi.com/2072-6651/6/5/1586
Autor:
Geoffrey K. Isbister, Jamie Seymour, Nicki Konstantakopoulos, Bernard V. McInerney, Jason Mulvenna, Wayne C. Hodgson, Diane L. Brinkman
Publikováno v:
Journal of Biological Chemistry. 289:4798-4812
The box jellyfish Chironex fleckeri produces extremely potent and rapid-acting venom that is harmful to humans and lethal to prey. Here, we describe the characterization of two C. fleckeri venom proteins, CfTX-A (∼40 kDa) and CfTX-B (∼42 kDa), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18fb2d2e87c8ff998103d3569b87d889
https://doi.org/10.1074/jbc.m113.534149
https://doi.org/10.1074/jbc.m113.534149
An examination of cardiovascular collapse induced by eastern brown snake (Pseudonaja textilis) venom
Autor:
Janeyuth Chaisakul, Wayne C. Hodgson, Sanjaya Kuruppu, Geoffrey K. Isbister, Nicki Konstantakopoulos
Publikováno v:
Toxicology Letters. 221:205-211
The Pseudonaja genus (Brown snakes) is widely distributed across Australia and bites account for significant mortality. Venom-induced consumption coagulopathy (VICC) and, less often, early cardiovascular collapse occur following envenoming by these s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c912778ebeb9f781bdabdf231e00820
https://doi.org/10.1016/j.toxlet.2013.06.235
https://doi.org/10.1016/j.toxlet.2013.06.235
Autor:
Helena C. Parkington, Wayne C. Hodgson, Nicki Konstantakopoulos, Janeyuth Chaisakul, Geoffrey K. Isbister
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 112:325-334
Pre-synaptic PLA(2) neurotoxins are important components of many Australasian elapid snake venoms. These toxins disrupt neurotransmitter release. Taipoxin, a pre-synaptic neurotoxin isolated from the venom of the coastal taipan (Oxyuranus scutellatus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426f0efcd0b2c13c5413aa0d6d220da4
https://doi.org/10.1111/bcpt.12048
https://doi.org/10.1111/bcpt.12048
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 59:166-170
Introduction: Chironex fleckeri is a large box jellyfish that has been labelled the ‘most venomous animal’ in the world. We have recently shown that the primary effect of C. fleckeri venom in vivo is cardiovascular collapse. This study utilised a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9765e756dbf1fd723eff0de620cbf6c9
https://doi.org/10.1016/j.vascn.2009.02.003
https://doi.org/10.1016/j.vascn.2009.02.003
Autor:
Geoffrey K. Isbister, Jennifer Schneider, Nicki Konstantakopoulos, Kelly Lee Winter, Jamie Seymour, Wayne C. Hodgson
Publikováno v:
Toxicology Letters. 179:118-123
Irukandji syndrome is usually characterized by delayed severe abdominal, back and chest pain associated with autonomic effects including diaphoresis, hypertension and, in severe cases, myocardial injury and pulmonary oedema. It is most often associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f17b4d20f2bf1763e83761965f1530
https://doi.org/10.1016/j.toxlet.2008.04.011
https://doi.org/10.1016/j.toxlet.2008.04.011
Autor:
Nicki Konstantakopoulos, Michael A. Quinn, Mark S. Baker, Harry M. Georgiou, Ian G. Campbell, Gregory E. Rice, Martin R. Larsen
Publikováno v:
Clinical Proteomics. 2:153-167
Epidemiological studies have shown that Asian populations display a lower incidence of hormone-dependant cancers, cardiovascular disease, osteoporosis, and menopausal ailments compared to Western societies. Available data support the proposal that lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2239ebd3659f03e052f91524b9d877f
https://doi.org/10.1007/bf02752498
https://doi.org/10.1007/bf02752498