Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicki Gray"'
Autor:
Fiona Hartley, Arwa Alageel, Ruth Appeltant, Nicki Gray, Emmanouela Repapi, Dagan Wells, Suzannah A Williams, Joanna Poulton
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 3, Pp 198-206 (2022)
Mitochondrial quality is implicated as a contributor to declining fertility with aging. We investigated mitochondrial transcripts in oocytes and their associated cumulus cells from mice of different ages using RNA-seq. Mice aged 3 weeks, 9 weeks, and
Externí odkaz:
https://doaj.org/article/22fb7ad38bde4bc8a274b9f09fa758f2
Autor:
Chathuranga L. Fonseka, Clare S. Hardman, Jeongmin. Woo, Randeep Singh, Janina Nahler, Jiahe Yang, Yi-Ling Chen, Achala Kamaladasa, Tehani Silva, Maryam Salimi, Nicki Gray, Tao Dong, Gathsaurie N. Malavige, Graham S. Ogg
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Group 2 innate lymphoid cells are activated during acute dengue viral infection in human, downregulate type I-IFN responsive gene and protein expression through Prostaglandin D2, and are permissive for productive dengue viral infection.
Externí odkaz:
https://doaj.org/article/1f029b0885fe424d822999d259a66359
Autor:
Hedia Chagraoui, Maiken S. Kristiansen, Juan Pablo Ruiz, Ana Serra-Barros, Johanna Richter, Elisa Hall-Ponselé, Nicki Gray, Dominic Waithe, Kevin Clark, Philip Hublitz, Emmanouela Repapi, Georg Otto, Paul Sopp, Stephen Taylor, Supat Thongjuea, Paresh Vyas, Catherine Porcher
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Mechanisms that operate during embryonic development to restrict cell fate are currently under investigation. Here the authors characterise the role of SCL/TAL1 at the onset of blood specification in embryonic development using mouse EB differentiati
Externí odkaz:
https://doaj.org/article/58afad89e66d460dbd6feaaa3566ef20
Autor:
Sant-Rayn Pasricha, Pei Jin Lim, Tiago L. Duarte, Carla Casu, Dorenda Oosterhuis, Katarzyna Mleczko-Sanecka, Maria Suciu, Ana Rita Da Silva, Kinda Al-Hourani, João Arezes, Kirsty McHugh, Sarah Gooding, Joe N. Frost, Katherine Wray, Ana Santos, Graça Porto, Emmanouela Repapi, Nicki Gray, Simon J. Draper, Neil Ashley, Elizabeth Soilleux, Peter Olinga, Martina U. Muckenthaler, Jim R. Hughes, Stefano Rivella, Thomas A. Milne, Andrew E. Armitage, Hal Drakesmith
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Hepcidin controls systemic iron levels by inhibiting intestinal iron absorption and iron recycling. Here, Pasricha et al. demonstrate that the hepcidin-chromatin locus displays HDAC3-mediated reversible epigenetic modifications during both erythropoi
Externí odkaz:
https://doaj.org/article/15032712babd4934b8cf9987f86cc0ba
Autor:
Cristina Di Genua, Ruggiero Norfo, Alba Rodriguez-Meira, Wei Xiong Wen, Roy Drissen, Christopher A.G. Booth, Benjamin Povinelli, Emmanouela Repapi, Nicki Gray, Joana Carrelha, Laura M. Kettyle, Lauren Jamieson, Wen Hao Neo, Supat Thongjuea, Claus Nerlov, Adam J. Mead
Publikováno v:
Haematologica, Vol 104, Iss 11 (2019)
Somatic mutations in acute myeloid leukemia are acquired sequentially and hierarchically. First, pre-leukemic mutations, such as t(8;21) that encodes AML1-ETO, are acquired within the hematopoietic stem cell (HSC) compartment, while signaling pathway
Externí odkaz:
https://doaj.org/article/63c14c0940654124844eb28a1e97c816
Autor:
Mirjam Schilling, Anne Bridgeman, Nicki Gray, Jonny Hertzog, Philip Hublitz, Alain Kohl, Jan Rehwinkel
Publikováno v:
Cells, Vol 9, Iss 6, p 1476 (2020)
The Zika virus (ZIKV) has received much attention due to an alarming increase in cases of neurological disorders including congenital Zika syndrome associated with infection. To date, there is no effective treatment available. An immediate response b
Externí odkaz:
https://doaj.org/article/3748a93844d043d385082590838025b5
Autor:
Valentine M. Macaulay, Stephen Taylor, Thomas Bogenrieder, Michael P. Sanderson, Ulrike Weyer-Czernilofsky, Freddie C. Hamdy, Rajeev Kumar, Adam G. Lambert, Kathryn Hutchinson, Cheng Han, Richard J. Bryant, Clare Verrill, Jack Mills, Eliot Osher, Guillaume Rieunier, Xiaoning Wu, Nicki Gray, Tamara Aleksic
Supplementary file containing: Supplementary methods Table S1: Primers, probes and siRNAs used in this study. Table S2: Demographics of men treated by radical prostatectomy for prostate cancer. Table S3: IGF-1R scores and clinical parameters in men u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573218d9a30e08fded720f68f497737d
https://doi.org/10.1158/0008-5472.22420502
https://doi.org/10.1158/0008-5472.22420502
Autor:
Valentine M. Macaulay, Stephen Taylor, Thomas Bogenrieder, Michael P. Sanderson, Ulrike Weyer-Czernilofsky, Freddie C. Hamdy, Rajeev Kumar, Adam G. Lambert, Kathryn Hutchinson, Cheng Han, Richard J. Bryant, Clare Verrill, Jack Mills, Eliot Osher, Guillaume Rieunier, Xiaoning Wu, Nicki Gray, Tamara Aleksic
Table S5 Genomic locations of IGF-1R binding in DU145 prostate cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83c6a445b56a1b4fda7bc9c0577b9df
https://doi.org/10.1158/0008-5472.22420505.v1
https://doi.org/10.1158/0008-5472.22420505.v1
Autor:
Valentine M. Macaulay, Stephen Taylor, Thomas Bogenrieder, Michael P. Sanderson, Ulrike Weyer-Czernilofsky, Freddie C. Hamdy, Rajeev Kumar, Adam G. Lambert, Kathryn Hutchinson, Cheng Han, Richard J. Bryant, Clare Verrill, Jack Mills, Eliot Osher, Guillaume Rieunier, Xiaoning Wu, Nicki Gray, Tamara Aleksic
Internalization of ligand-activated type I IGF receptor (IGF1R) is followed by recycling to the plasma membrane, degradation or nuclear translocation. Nuclear IGF1R reportedly associates with clinical response to IGF1R inhibitory drugs, yet its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d147892df557bed6302e759b523de0e
https://doi.org/10.1158/0008-5472.c.6510674.v1
https://doi.org/10.1158/0008-5472.c.6510674.v1
Autor:
Chathuranga L. Fonseka, Clare S. Hardman, Jeongmin. Woo, Randeep Singh, Janina Nahler, Jiahe Yang, Yi-Ling Chen, Achala Kamaladasa, Tehani Silva, Maryam Salimi, Nicki Gray, Tao Dong, Gathsaurie N. Malavige, Graham S. Ogg
Publikováno v:
Communications biology. 5(1)
Mast cell products and high levels of type 2 cytokines are associated with severe dengue disease. Group 2 innate lymphoid cells (ILC2) are type-2 cytokine-producing cells that are activated by epithelial cytokines and mast cell-derived lipid mediator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b749d2620e7ad607d48bf5c4e673187a
https://pubmed.ncbi.nlm.nih.gov/35869167
https://pubmed.ncbi.nlm.nih.gov/35869167