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Impaired Epstein-Barr Virus-Specific Neutralizing Antibody Response during Acute Infectious Mononucleosis Is Coincident with Global B-Cell Dysfunction

Autor: Alan B. Rickinson, Nick Tellam, Henry H. Balfour, Denis J. Moss, Michelle N. Wykes, Kristin A. Hogquist, Vijayendra Dasari, Rajiv Khanna, Corey Smith, Archana Panikkar, Andrew D. Hislop

Publikováno v: Journal of Virology. 89:9137-9141

Here we present evidence for previously unappreciated B-cell immune dysregulation during acute Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM). Longitudinal analyses revealed that patients with acute IM have undetectable EBV-specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0616e8eb21ec2dbbc5d3f266f9ed7f2
https://doi.org/10.1128/jvi.01293-15

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Cytokine-Mediated Loss of Blood Dendritic Cells During Epstein-Barr Virus-Associated Acute Infectious Mononucleosis: Implication for Immune Dysregulation

Autor: Kristin A. Hogquist, Rajiv Khanna, Alan B. Rickinson, Archana Panikkar, Vijayendra Dasari, Nick Tellam, Denis J. Moss, Michelle N. Wykes, Corey Smith, Andrew D. Hislop, Henry H. Balfour

Publikováno v: The Journal of infectious diseases. 212(12)

Acute infectious mononucleosis (IM) is associated with altered expression of inflammatory cytokines and disturbed T-cell homeostasis, however, the precise mechanism of this immune dysregulation remains unresolved. In the current study we demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9814999a079eaf0b31eff49b8269f21f
https://pubmed.ncbi.nlm.nih.gov/26080368

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