Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nick Smithers"'
Autor:
Nick Smithers
Publikováno v:
Intimate Partner Violence ISBN: 9781315169842
The Scottish Government follow the UN line that “Domestic abuse is both a cause and consequence of gender inequality”. For three years the Scottish Government funded a development post to raise awareness of men’s experience with the hope of imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4652230dc216e9fba60187dba35f083f
https://doi.org/10.4324/9781315169842-10
https://doi.org/10.4324/9781315169842-10
Autor:
Philip Alan Skone, Donald O. Somers, Marion C. Dickson, Nick Smithers, Ann Louise Walker, Thomas George Christopher Hayhow, Stuart G. Leach, Karen Leavens, Clement Douault, Emma J. Jones, Dorothy Elwes, Robert J. Watson, Margarete Neu, Robert P. Davis, Matthew Gray, Neil Stuart Garton, Clare I. Hobbs, Alex Preston, Michael David Barker, Vipulkumar Kantibhai Patel, Cesar Ramirez-Molina, Paul S. Carter, Scott McCleary, Gordon G. Weingarten, Huw D. Lewis, Francis Louis Atkinson, John Liddle, Tracy Jane Shipley, Neil R. Curtis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6188-6194
The lead optimisation of the diaminopyrimidine carboxamide series of spleen tyrosine kinase inhibitors is described. The medicinal chemistry strategy was focused on optimising the human whole blood activity whilst achieving a sufficient margin over l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fce9afb90ca4e724d4726df2268b6f
https://doi.org/10.1016/j.bmcl.2011.07.082
https://doi.org/10.1016/j.bmcl.2011.07.082
Publikováno v:
FEBS Letters. 506:85-90
Monocyte chemoattractant protein-1 (MCP-1) has been implicated as a powerful pro-inflammatory mediator and may represent a potentially important, therapeutic opportunity for treatment of inflammatory disease and atherosclerosis. To further investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aa9ffb0efc154e482910b1eb120edf
https://doi.org/10.1016/s0014-5793(01)02895-2
https://doi.org/10.1016/s0014-5793(01)02895-2
Autor:
Nick Smithers, Valerie A. Kelly, S. L. Martin, Mark R. Edbrooke, A. J. Winder, Michael I. Bird, Christopher J. Britten, Sara J. Witham
Publikováno v:
Biochemical Society transactions. 25(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186e469f52f2d38ce0423ab8374f00bb
https://pubmed.ncbi.nlm.nih.gov/9388566
https://pubmed.ncbi.nlm.nih.gov/9388566
Autor:
Nick Smithers, Philippa Rollins, Sara J. Witham, Helen Sadler, Keith P. Ray, Roberto Solari, Nicola Thompson, S Grenfell
Publikováno v:
Cytokine. 3(1)
In this study we have examined the effect of agents known to perturb certain signal transduction pathways on the biological responses of target cells to stimulation with interleukin-1 (IL-1). In the murine thymoma cell line EL4, IL-1 stimulation resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faf12fbdfa96fda58319e6c995e1034
https://pubmed.ncbi.nlm.nih.gov/1715770
https://pubmed.ncbi.nlm.nih.gov/1715770
Publikováno v:
Biochemical Society Transactions. 25:426S-426S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3212423440429f087d7266fa517faf
https://doi.org/10.1042/bst025426s
https://doi.org/10.1042/bst025426s
Publikováno v:
Biochemical Society Transactions. 23:165S-165S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfdb61e856ce53986df03f121afc32e
https://doi.org/10.1042/bst023165s
https://doi.org/10.1042/bst023165s