Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nick R Lemoine"'
Autor:
Ming Yuan, Xuefei Gao, Louisa S Chard, Zarah Ali, Jahangir Ahmed, Yunqing Li, Pentao Liu, Nick R Lemoine, Yaohe Wang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
The current method for creation of vaccinia virus (VACV) vectors involves using a selection and purification marker, however inclusion of a gene without therapeutic value in the resulting vector is not desirable for clinical use. The Cre-LoxP system
Externí odkaz:
https://doaj.org/article/877a270d03ca43068bd8606fc497f5da
Autor:
Enrique Miranda, Hector Maya Pineda, Daniel Öberg, Gioia Cherubini, Zita Garate, Nick R Lemoine, Gunnel Halldén
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46617 (2012)
Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies. The replication-selective mutants AdΔΔ and dl922-947, defective in pRb-binding, have bee
Externí odkaz:
https://doaj.org/article/a3cecce52b2349eab6e0859e5b5b5795
Autor:
Gunnel Halldén, Nick R. Lemoine, Enrique Miranda, Derek Davies, Daniel Öberg, Katrina Sweeney, Stephan Leitner
Purpose: Pancreatic adenocarcinoma is a rapidly progressive malignancy that is highly resistant to current chemotherapeutic modalities and almost uniformly fatal. We show that a novel targeting strategy combining oncolytic adenoviral mutants with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc5029746fc668de01fcb8e38d1b7c1
https://doi.org/10.1158/1078-0432.c.6517719
https://doi.org/10.1158/1078-0432.c.6517719
Autor:
Tatjana Crnogorac-Jurcevic, Nick R. Lemoine, William Greenhalf, Eithne Costello, John Neoptolemos, Núria Malats, Francisco X. Real, Cristiane Murta-Nascimento, Luisa Guarner (posthumous), Stephen P. Pereira, Hemant M. Kocher, Stephen W. Duffy, Darren Ennis, Laurent Dumartin, Wasfi Alrawashdeh, Richard Jones, Nathalie J. Massat, Tomasz P. Radon
Correlation of the three urinary biomarkers and plasma CA19.9 (CA19.9p). A, Correlation plots (Navy blue: Healthy; Turquoise: chronic pancreatitis (CP); Purple: pancreatic adenocarcinoma (PDAC). B, Pearson correlation coefficients and corresponding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ad9299d2c43e0ae7b751afd99356ff
https://doi.org/10.1158/1078-0432.22455281.v1
https://doi.org/10.1158/1078-0432.22455281.v1
Autor:
Georges Vassaux, Kevin Harrington, Nick R. Lemoine, Richard Iggo, Mohan Hingorani, Miguel Quintanilla, Jerome Burnet, Cécilia Hindorf, Pilar Martin-Duque, Sophie Conchon, Patrick Baril, Andrew Merron, Inge Peerlinck
Purpose: The Na/I symporter (hNIS) promotes concentration of iodine in cells. In cancer gene therapy, this transgene has potential as a reporter gene for molecular imaging of viral biodistribution and as a therapeutic protein promoting 131I-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c93db3c809aec6703a14133fda6ac6
https://doi.org/10.1158/1078-0432.c.6517387.v1
https://doi.org/10.1158/1078-0432.c.6517387.v1
Autor:
Tatjana Crnogorac-Jurcevic, Nick R. Lemoine, William Greenhalf, Eithne Costello, John Neoptolemos, Núria Malats, Francisco X. Real, Cristiane Murta-Nascimento, Luisa Guarner (posthumous), Stephen P. Pereira, Hemant M. Kocher, Stephen W. Duffy, Darren Ennis, Laurent Dumartin, Wasfi Alrawashdeh, Richard Jones, Nathalie J. Massat, Tomasz P. Radon
Diagnostic performance of urine biomarkers in discriminating pancreatic adenocarcinoma all stages (A-C) and stage I-II (D-F) from chronic pancreatitis patients. A, ROC curves of PDAC (n=143) versus CP (n=62) patients for individual urine biomarkers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a17e64dbbf0da64021764b89243ae9
https://doi.org/10.1158/1078-0432.22455278
https://doi.org/10.1158/1078-0432.22455278
Autor:
Tatjana Crnogorac-Jurcevic, Nick R. Lemoine, William Greenhalf, Eithne Costello, John Neoptolemos, Núria Malats, Francisco X. Real, Cristiane Murta-Nascimento, Luisa Guarner (posthumous), Stephen P. Pereira, Hemant M. Kocher, Stephen W. Duffy, Darren Ennis, Laurent Dumartin, Wasfi Alrawashdeh, Richard Jones, Nathalie J. Massat, Tomasz P. Radon
Expression of the protein biomarkers in pancreatic cancer tissues. A, Immunohistochemical analysis of REG1A: i) REG1A in poorly differentiated PDAC, ii) luminal REG1A in malignant glands. B, TFF1: i) heterogenous expression in cancer,, ii) luminal TF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5485844746c5b46d185bc947e38af66
https://doi.org/10.1158/1078-0432.22455269
https://doi.org/10.1158/1078-0432.22455269
Autor:
Tatjana Crnogorac-Jurcevic, Nick R. Lemoine, William Greenhalf, Eithne Costello, John Neoptolemos, Núria Malats, Francisco X. Real, Cristiane Murta-Nascimento, Luisa Guarner (posthumous), Stephen P. Pereira, Hemant M. Kocher, Stephen W. Duffy, Darren Ennis, Laurent Dumartin, Wasfi Alrawashdeh, Richard Jones, Nathalie J. Massat, Tomasz P. Radon
Exploratory comparison of plasma CA19.9 and the urine biomarker panel in discriminating early pancreatic adenocarcinoma from chronic pancreatitis patients. A, ROC curves of the biomarker panel with corresponding plasma CA19.9 alone and in combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31725e27e81ab9122d98b18ec38d90ca
https://doi.org/10.1158/1078-0432.22455275
https://doi.org/10.1158/1078-0432.22455275
Autor:
Gunnel Halldén, Nick R. Lemoine, Celina Costas, Katrina Sweeney, Virginie Adam, Eva Yanover, Daniel Öberg
Supplementary Data from Improved Potency and Selectivity of an Oncolytic E1ACR2 and E1B19K Deleted Adenoviral Mutant in Prostate and Pancreatic Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d297f4986fcfc264dd343175f8ff3d1
https://doi.org/10.1158/1078-0432.22440346
https://doi.org/10.1158/1078-0432.22440346
Autor:
Georges Vassaux, Kevin Harrington, Nick R. Lemoine, Richard Iggo, Mohan Hingorani, Miguel Quintanilla, Jerome Burnet, Cécilia Hindorf, Pilar Martin-Duque, Sophie Conchon, Patrick Baril, Andrew Merron, Inge Peerlinck
Supplementary Data from Targeted Radionuclide Therapy Using a Wnt-Targeted Replicating Adenovirus Encoding the Na/I Symporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3931bc61633534a806eb9a8bc68967f1
https://doi.org/10.1158/1078-0432.22440007.v1
https://doi.org/10.1158/1078-0432.22440007.v1