Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nick Papadopoulos"'
Autor:
Yuxuan Wang, Christopher Douville, Joshua Cohen, Chetan Bettegowda, Nick Papadopoulos, Ken Kinzler, Bert Vogelstein
Publikováno v:
Cancer Research. 83:6609-6609
The analysis of cell-free DNA (cfDNA) from plasma offers great promise for the earlier detection of cancer. At present, changes in DNA sequence, methylation, or copy number are the most sensitive ways to detect the presence of cancer. To increase the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2aa4b936f9451721bc356338a96c997
https://doi.org/10.1158/1538-7445.am2023-6609
https://doi.org/10.1158/1538-7445.am2023-6609
Autor:
Adnan Nagrial, David Goldstein, Niall C. Tebbutt, Bert Vogelstein, Joshua D. Cohen, Lu Li, Andrew Haydon, Kenneth W. Kinzler, Koen Simons, Peter Gibbs, Jeanne Tie, Cristian Tomasetti, D W M Tai, Prasad Cooray, Nick Papadopoulos, C L Wolfgang, Matthew Burge, Lara Lipton, Belinda Lee, Mehrdad Nikfarjam, Ammar A. Javed, Marion Harris, Benjamin N. J. Thomson, A M Lennon, B. Lawrence
Publikováno v:
Annals of Oncology. 30:1472-1478
In early-stage pancreatic cancer, there are currently no biomarkers to guide selection of therapeutic options. This prospective biomarker trial evaluated the feasibility and potential clinical utility of circulating tumor DNA (ctDNA) analysis to info
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25da70636ac384063a30f777fc3c5558
https://doi.org/10.1093/annonc/mdz200
https://doi.org/10.1093/annonc/mdz200
Autor:
Nick Papadopoulos
Publikováno v:
Social Defences Against Anxiety ISBN: 9780429480300
Social Defences Against Anxiety
Social Defences Against Anxiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5390fbe5a770112c5189e6b2211af195
https://doi.org/10.4324/9780429480300-7
https://doi.org/10.4324/9780429480300-7
Autor:
Nick Papadopoulos, Kenneth W. Kinzler, Mark Tacey, J. Roebert, Ben Tran, Robert L. Strausberg, Isaac Kinde, Jayesh Desai, MacDonald J. Christie, Peter Gibbs, Rachel Wong, Luis A. Diaz, Yuxuan Wang, Hui-Li Wong, Jeanne Tie, Christos S. Karapetis, Bert Vogelstein, Madhu Sudan Singh
Publikováno v:
Annals of Oncology. 26:1715-1722
Early indicators of treatment response in metastatic colorectal cancer (mCRC) could conceivably be used to optimize treatment. We explored early changes in circulating tumor DNA (ctDNA) levels as a marker of therapeutic efficacy.This prospective stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b4504868e1796c4f4e73dfa9cb0b19
https://doi.org/10.1093/annonc/mdv177
https://doi.org/10.1093/annonc/mdv177
Autor:
Luigi Marchionni, Ming Zhang, Nick Papadopoulos, Mohamad E. Allaf, Michael A. Gorin, George J. Netto, Maria Angelica Mendoza Rodriguez, Charles G. Drake, Michael C. Haffner, Michael H. Johnson, Mark W. Ball, Hans J. Hammers
Publikováno v:
Journal of Urology. 195
INTRODUCTION AND OBJECTIVES: Previous studies have correlated response to PD-1 blockade with PD-L1 over-expression, as well as cell-mediated immune transcripts. However, factors associated with long-term, durable response to nivolumab in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ea98e4eb9bdba4a3e1a16e6e1b3e389
https://doi.org/10.1016/j.juro.2016.02.1894
https://doi.org/10.1016/j.juro.2016.02.1894
Objectives: To systematically review and meta-analyse existing evidence on the association between folate/B12, and depression among the aged people. Methods: Following PRISMA/STROBE guidelines, the Medline abstracts were retrieved using an algorithm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::54a5ea4bc81031d0f6e57c8dadc26ae2
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3168369
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3168369
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9530-9535
The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Although massively parallel sequencing instruments are in principle well suited to this task, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca35d4e53a2111315b4f877f1e6584e3
https://doi.org/10.1073/pnas.1105422108
https://doi.org/10.1073/pnas.1105422108
Autor:
Jaclyn A. Biegel, Sueli Mieko Oba Shinjo, Xiaosong Zhang, Victor E. Velculescu, Yiping He, Stephen T. Keir, Tom Curran, Mitchel S. Berger, Daniela S. Gerhard, Nick Papadopoulos, D. Williams Parsons, Michael D. Taylor, Hai Yan, Adam C. Resnick, Peter C. Burger, Gregory J. Riggins, Giovanni Parmigiani, Darell D. Bigner, Zev A. Binder, Doug R. Smith, Henry S. Friedman, Roger E. McLendon, Scott R. VandenBerg, Jane E. Minturn, Carlos Clara, Alexander R. Judkins, Simina M. Boca, Siân Jones, George I. Jallo, Rachel Karchin, Kenneth W. Kinzler, Chetan Bettegowda, Gary L. Gallia, Meng Li, Yuri Nikolsky, Peter C. Phillips, James Hartigan, Rebecca J. Leary, Phillip B. Storm, Hannah Carter, Suely Kazue Nagahashi Marie, Josue Samayoa, Paul A. Northcott, Bert Vogelstein, B.K. Ahmed Rasheed, Jimmy Lin, Daniel W. Fults
Publikováno v:
Science. 331:435-439
Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high-density microarrays and sequenced all known protein-coding genes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eecda1f1d0b7cf8eab59dc6fcb1ee71
https://doi.org/10.1126/science.1198056
https://doi.org/10.1126/science.1198056
Autor:
Sanford D. Markowitz, Jordan M. Cummins, James K V Willson, Kenneth W. Kinzler, Siân Jones, Victor E. Velculescu, Tobias Sjöblom, Nick Papadopoulos, Ben Ho Park, Tian Li Wang, Yuri Nikolsky, Ramon Parsons, Joseph Willis, Dawn M. Dawson, Giovanni Parmigiani, Bert Vogelstein, Simina M. Boca, Laura D. Wood, Jimmy Lin, Levy Kopelovich, D. Williams Parsons, Len A. Pennacchio, Rebecca J. Leary, Tatiana Nikolskaya
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16224-16229
We have performed a genome-wide analysis of copy number changes in breast and colorectal tumors using approaches that can reliably detect homozygous deletions and amplifications. We found that the number of genes altered by major copy number changes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5400a78d12ba15f2b80a7ed94d4e5c5
https://doi.org/10.1073/pnas.0808041105
https://doi.org/10.1073/pnas.0808041105
Autor:
Aldrich Thomas H, Elena Burova, Jennifer A. Griffiths, John S. Rudge, Elizabeth Pasnikowski, Thomas J. Daly, Vivian Wong, James P. Fandl, Donald M. McDonald, Gavin Thurston, Nick Papadopoulos, Ella Ioffe, George D. Yancopoulos, Christopher Daly
Publikováno v:
Proceedings of the National Academy of Sciences. 103:15491-15496
Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of normal and pathologic angiogenesis. One prevailing model suggests that in these settings, Ang-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcafc5a49a15951b10cdffe3c44533fb
https://doi.org/10.1073/pnas.0607538103
https://doi.org/10.1073/pnas.0607538103