Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nick P. Hughes"'
Autor:
Shaveta Mehta, Nick P. Hughes, Sonia Li, Adrian Jubb, Rosie Adams, Simon Lord, Lefteris Koumakis, Ruud van Stiphout, Anwar Padhani, Andreas Makris, Francesca M. Buffa, Adrian L. Harris
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 109-116 (2016)
Anti-VEGF antibody bevacizumab has prolonged progression-free survival in several cancer types, however acquired resistance is common. Adaption has been observed pre-clinically, but no human study has shown timing and genes involved, enabling formula
Externí odkaz:
https://doaj.org/article/95b51e0dd07d4b28af30ade436d7ddd8
Autor:
Jessica Garcia, Nick Kamps-Hughes, Florence Geiguer, Sébastien Couraud, Brice Sarver, Léa Payen, Cristian Ionescu-Zanetti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Circulating cell-free DNA (cfDNA) has the potential to be a specific biomarker for the therapeutic management of lung cancer patients. Here, a new sequencing error-reduction method based on molecular amplification pools (MAPs) was utilized t
Externí odkaz:
https://doaj.org/article/da8aee7bdc1c403a8d63c53a6d8142ba
Publikováno v:
PeerJ, Vol 3, p e1527 (2015)
Here we present a genome-wide method for de novo identification of enhancer regions. This approach enables massively parallel empirical investigation of DNA sequences that mediate transcriptional activation and provides a platform for discovery of re
Externí odkaz:
https://doaj.org/article/29af53d8ac044a02a2f3e74ee2f2fb0e
Autor:
Nick Kamps-Hughes, Andrew McUsic, Laurie Kurihara, Timothy T Harkins, Prithwish Pal, Claire Ray, Cristian Ionescu-Zanetti
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195272 (2018)
The accurate detection of ultralow allele frequency variants in DNA samples is of interest in both research and medical settings, particularly in liquid biopsies where cancer mutational status is monitored from circulating DNA. Next-generation sequen
Externí odkaz:
https://doaj.org/article/01d75b1d749d44488c8b2a52ab9cce3a