Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Nick P Talbot"'
Autor:
James Melhorn, Asma Alamoudi, Alexander J. Mentzer, Emily Fraser, Anastasia Fries, Mark Philip Cassar, Andrew Kwok, Julian Charles Knight, Betty Raman, Nick P Talbot, Nayia Petousi
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background and aimIn acute severe COVID-19, patients present with lung inflammation and vascular injury, accompanied by an exaggerated cytokine response. In this study, our aim was to describe the inflammatory and vascular mediator profiles in patien
Externí odkaz:
https://doaj.org/article/e6f7c94444bd4c858af9ae900fda82b7
Autor:
David A Holdsworth, Rebecca Chamley, Rob Barker-Davies, Oliver O'Sullivan, Peter Ladlow, James L Mitchell, Dominic Dewson, Daniel Mills, Samantha L J May, Mark Cranley, Cheng Xie, Edward Sellon, Joseph Mulae, Jon Naylor, Betty Raman, Nick P Talbot, Oliver J Rider, Alexander N Bennett, Edward D Nicol
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0267392 (2022)
IntroductionThere have been more than 425 million COVID-19 infections worldwide. Post-COVID illness has become a common, disabling complication of this infection. Therefore, it presents a significant challenge to global public health and economic act
Externí odkaz:
https://doaj.org/article/3fe13b7405a34c5898941a96f31bcf13
Autor:
Nayia Petousi, Nick P Talbot, Peter A Robbins, Mona Bafadhel, Annabel H Nickol, Peter Santer, Matthew C Frise, Anne McGahey, Richard Baskerville
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Background Increased iron availability modifies cardiorespiratory function in healthy volunteers and improves exercise capacity and quality of life in patients with heart failure or pulmonary hypertension. We hypothesised that intravenous iron would
Externí odkaz:
https://doaj.org/article/d3152b52eb28409f8a8380b35a0c1c2f
Autor:
Nayia Petousi, Nick P Talbot, Ian Pavord, Peter A Robbins, Nicholas M J Smith, John Couper, Christopher J Fullerton, Graham Richmond, Gus Hancock, Grant A D Ritchie
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Introduction In asthma, lung function measures are often discordant with clinical features such as disease activity or control.Methods We investigated a novel technique that provides a measure (σCL) of unevenness (inhomogeneity) in lung inflation/de
Externí odkaz:
https://doaj.org/article/b32ccc74944a4ff498ea812b739c607e
Autor:
Quentin P P Croft, Federico Formenti, Nick P Talbot, Daniel Lunn, Peter A Robbins, Keith L Dorrington
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67886 (2013)
The human pulmonary vasculature constricts in response to hypercapnia and hypoxia, with important consequences for homeostasis and adaptation. One function of these responses is to direct blood flow away from poorly-ventilated regions of the lung. In
Externí odkaz:
https://doaj.org/article/4b3c912a401d41a18f45a521c6e1c62b
Autor:
Thomas G Smith, Jerome T Brooks, George M Balanos, Terence R Lappin, D Mark Layton, Dawn L Leedham, Chun Liu, Patrick H Maxwell, Mary F McMullin, Christopher J McNamara, Melanie J Percy, Christopher W Pugh, Peter J Ratcliffe, Nick P Talbot, Marilyn Treacy, Peter A Robbins
Publikováno v:
PLoS Medicine, Vol 3, Iss 7, p e290 (2006)
BackgroundThe von Hippel-Lindau tumour suppressor protein-hypoxia-inducible factor (VHL-HIF) pathway has attracted widespread medical interest as a transcriptional system controlling cellular responses to hypoxia, yet insights into its role in system
Externí odkaz:
https://doaj.org/article/52c8f8c7977a47c5b133c24f88912721
Autor:
Hung‐Yuan Cheng, Matthew C. Frise, M. Kate Curtis, Nicole K. Bart, Nayia Petousi, Nick P. Talbot, George M. Balanos, Peter A. Robbins, Keith L. Dorrington
Publikováno v:
Physiological Reports, Vol 7, Iss 13, Pp n/a-n/a (2019)
Abstract In older individuals, pulmonary artery pressure rises markedly during exercise, probably due in part to increased pulmonary vascular resistance and in part to an increase in left‐heart filling pressure. Older individuals also show more mar
Externí odkaz:
https://doaj.org/article/5a8b2987b19f460dbf8a03bf4f924bc8
Autor:
Oliver O’Sullivan, David A. Holdsworth, Peter Ladlow, Robert M. Barker-Davies, Rebecca Chamley, Andrew Houston, Samantha May, Dominic Dewson, Daniel Mills, Kayleigh Pierce, James Mitchell, Cheng Xie, Edward Sellon, Jon Naylor, Joseph Mulae, Mark Cranley, Nick P. Talbot, Oliver J. Rider, Edward D. Nicol, Alexander N. Bennett
Publikováno v:
Sports Medicine - Open. 9
Background The COVID-19 pandemic has led to significant morbidity and mortality, with the former impacting and limiting individuals requiring high physical fitness, including sportspeople and emergency services. Methods Observational cohort study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::060e9cf871c1ba6a0d07b2539595a9b7
https://doi.org/10.1186/s40798-023-00552-0
https://doi.org/10.1186/s40798-023-00552-0
Autor:
Nicholas M. J. Smith, Snapper R. M. Magor-Elliott, Christopher J. Fullerton, John H. Couper, Graham Richmond, Gus Hancock, Grant A. D. Ritchie, Peter A. Robbins, Nick P. Talbot, Nayia Petousi
Publikováno v:
Frontiers in Physiology. 13
Early diagnosis and disease phenotyping in COPD are currently limited by the use of spirometry, which may remain normal despite significant small-airways disease and which may not fully capture a patient’s underlying pathophysiology. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205813bcec6c251142ee6b9319d2c938
Autor:
Snapper R. M. Magor-Elliott, Asma Alamoudi, Rebecca R. Chamley, Haopeng Xu, Tishan Wellalagodage, Rory P. McDonald, David O’Brien, Jonathan Collins, Ben Coombs, James Winchester, Ed Sellon, Cheng Xie, Dominic Sandhu, Christopher J. Fullerton, John H. Couper, Nicholas M. J. Smith, Graham Richmond, Mark P. Cassar, Betty Raman, Nick P. Talbot, Alexander N. Bennett, Edward D. Nicol, Grant A. D. Ritchie, Nayia Petousi, David A. Holdsworth, Peter A. Robbins
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(5)
The longer-term effects of COVID-19 on lung physiology remain poorly understood. Here, a new technique, computed cardiopulmonography (CCP), was used to study two COVID-19 cohorts (MCOVID and C-MORE-LP) at both ∼6 and ∼12 mo after infection. CCP i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ae0fc4e1cb65ba675d500061e9f35d
https://pubmed.ncbi.nlm.nih.gov/36173325
https://pubmed.ncbi.nlm.nih.gov/36173325