Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nick Occleston"'
Autor:
Jim Bush, Sharon O'kane, Mark Cooper, Mark W. J. Ferguson, David Fairlamb, Nick Occleston, Tracey Mason, Hugh G. Laverty
Publikováno v:
Wound Repair and Regeneration. 19:s38-s48
Scarring in the skin following surgery or trauma may be associated with adverse aesthetic, functional, growth and psychological effects, such that both physicians and patients regard it as important to minimize the appearance of scars. The prophylact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c6fc49abc489d2cdbd6d32f293882e
https://doi.org/10.1111/j.1524-475x.2011.00711.x
https://doi.org/10.1111/j.1524-475x.2011.00711.x
Autor:
Mark W. J. Ferguson, John Little, David Fairlamb, Richard B. Jones, Mark Johnson, Nick Occleston, Hugh G. Laverty, Sharon O'kane
Publikováno v:
Journal of Cutaneous Medicine and Surgery. 14:223-232
Background: The pig is an accepted species for evaluating the safety of molecules in dermal wound healing indications; however, the sizes of wounds assessed have not always been comparable to large incisions encountered clinically. Objective: To deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d687fba97f421eaee783752d99d91e
https://doi.org/10.2310/7750.2010.09069
https://doi.org/10.2310/7750.2010.09069
Autor:
Abdul Sattar, Neil French, Adam Boanas, M.J.W. Ferguson, Hugh Laverty, Sharon O'kane, Anthony D. Metcalfe, Nick Burgoyne, Nick Occleston
Publikováno v:
Wound Repair and Regeneration. 17:A10-A53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf944bb3cd34e119fb2755b1a282d717
https://doi.org/10.1111/j.1524-475x.2009.00469.x
https://doi.org/10.1111/j.1524-475x.2009.00469.x
Publikováno v:
Drug Discovery Today. 13:973-981
Published literature shows that both physicians and patients are highly concerned about scarring and value even small improvements in scar appearance. Both severe and relatively minor scars can have a significant psychological impact on patients, irr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882648025202111c191fa985a3140610
https://doi.org/10.1016/j.drudis.2008.08.009
https://doi.org/10.1016/j.drudis.2008.08.009
Publikováno v:
The International Journal of Lower Extremity Wounds. 7:160-168
Published literature shows that both physicians and their patients are highly concerned about scarring, even relatively minor scars and those that can be concealed by clothing. Furthermore, both patients and their physicians value any opportunities t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b51ca6a255efb2f0adc3dde9e2e95f9
https://doi.org/10.1177/1534734608322983
https://doi.org/10.1177/1534734608322983
Autor:
Anthony D. Metcalfe, Kerry Nield, Nicholas J. Burgoyne, Adam Boanas, Sharon O'kane, Nick Occleston, Mark William James Ferguson
Scarring is a major cause of physical and psychological morbidity and, whilst a variety of model systems exist that have increased our understanding of the pathways and processes underlying scar formation, they have typically not translated to the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a88211c9507f51227ec0e44d4f3cf0e
https://doi.org/10.1533/9780857093301.1.112
https://doi.org/10.1533/9780857093301.1.112
Autor:
Kerry Nield, Adam Boanas, Mark W. J. Ferguson, Nicholas J. Burgoyne, Nick Occleston, Anthony D. Metcalfe, Sharon O'kane
Publikováno v:
Dermatology Research and Practice
Dermatology Research and Practice, Vol 2010 (2010)
Dermatology Research and Practice, Vol 2010 (2010)
Scarring in the skin after trauma, surgery, burn or sports injury is a major medical problem, often resulting in loss of function, restriction of tissue movement and adverse psychological effects. Whilst various studies have utilised a range of model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c67f68465b99ce6b156149051ef32d
https://pubmed.ncbi.nlm.nih.gov/20811598
https://pubmed.ncbi.nlm.nih.gov/20811598
Publikováno v:
Dermatology Research and Practice, Vol 2010 (2010)
Dermatology Research and Practice
Dermatology Research and Practice
Many patients are dissatisfied with scars on both visible and non-visible body sites and would value any opportunity to improve or minimise scarring following surgery. Approximately 44 million procedures in the US and 42 million procedures in the EU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc27970b153a890a9071488eb7884b4
https://doaj.org/article/4cbdcaf9cfd84c6583cd3179b266d53f
https://doaj.org/article/4cbdcaf9cfd84c6583cd3179b266d53f
Publikováno v:
Expert opinion on investigational drugs. 18(8)
Disfiguring scarring in the skin is an area of high medical need. Current treatments for scarring have variable or limited effectiveness and have typically not been evaluated in randomized, controlled, double-blind clinical trials. The prophylactic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5437edcf2a0235140a88b3d8016f6931
https://pubmed.ncbi.nlm.nih.gov/19604123
https://pubmed.ncbi.nlm.nih.gov/19604123
Autor:
Jonathan A L Duncan, Gaynor James, Jonquille Chantrey, Sharon O'kane, Anna Ludlow, Tracey Mason, Karen So, Nick Occleston, Hugh G. Laverty, Abdul Sattar, Lisa D. Taylor, Mark W. J. Ferguson, James Bush, Piyush Durani, Jeremy S Bond
Publikováno v:
Lancet (London, England). 373(9671)
Summary Background Research into mechanisms of skin scarring identified transforming growth factor β3 (TGFβ3) as a potential antiscarring therapy. We assessed scar improvement with avotermin (recombinant, active, human TGFβ3). Methods In three dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d1babae958fe60487003248080a2c9
https://pubmed.ncbi.nlm.nih.gov/19362658
https://pubmed.ncbi.nlm.nih.gov/19362658