Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nick M. Drayer"'
Autor:
Ken K. Ong, Nick M Drayer, Leslie A. Perry, David B. Dunger, David J. Morrell, Michael A. Preece, Les Cox, Marion L. Ahmed
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:899-905
Leptin may have a role in the initiation of puberty and the regulation of subsequent weight gain, but this hypothesis has not been tested by longitudinal study. We report data from 40 normal children (20 boys and 20 girls) followed from 8-16 yr of ag
Publikováno v:
Medical and Pediatric Oncology, 21(1), 14-18
Bone age was assessed in children with acute lymphoblastic leukaemia (ALL) using the Tanner-Whitehouse II method. X-rays of the left hand (wrist) were made at diagnosis and annually until 5 years after diagnosis. A total of 164 X-rays from 40 patient
Autor:
Nick M. Drayer, G.P.B. Kraan
Publikováno v:
Steroids, 55(4), 159-164. ELSEVIER SCIENCE INC
A urinary method of determining the cortisol production rate (CPR) in children was studied under physiologic conditions by administration of low amounts of [1,2,3,4-13C]cortisol. The CPR in three patients with multiple pituitary deficiency ranged fro
Publikováno v:
Diabetes care. 21(5)
OBJECTIVE In cross-sectional studies of subjects with IDDM, the relationship between suboptimal pubertal growth, glycemic control, and abnormal insulin-like growth factor 1 (IGFI) levels has proved difficult to define. The objective of this study was
Autor:
Gijsbert P.B. Kraan, Kees T. van Wee, Daan van Leusen, Gijs T. Nagel, Nick M. Drayer, Jan C. van der Molen, B.G. Wolthers
Publikováno v:
Steroids. 58(10)
This report describes the synthesis of 6 alpha, 17,21- and 6 beta, 17,21-trihydroxypregn-4-ene-3,20-dione, 6 alpha, 7,21- and 6 beta, 11 beta, 21-trihydroxypregn-4-ene-3,20-dione, and--for the first time--that of 6 alpha, 21- and 6 beta, 21-dihydroxy
Publikováno v:
Steroids. 44:293-300
The preparation of [1,2,3,4- 13 C] cortisol 21-acetate by total synthesis is described. The 13 C labels are introduced in a way analogous to the one described by us previously for the synthesis of testosterone and estradiol. The cortisol dihydroxyace
Autor:
Nick M. Drayer, H.J.G.-M. Derks
Publikováno v:
Steroids, 31(2), 289-305. ELSEVIER SCIENCE INC
The 24 hours urines of six two days old fullterm newborn infants were investigated for polar corticosteroids. 6alpha-hydroxy-tetrahydrocortisone, 6alpha-hydroxy-20alpha-cortolone and 6alpha-hydroxy-20beta-cortolone were identified by gas chromatograp
Autor:
Nick M. Drayer, H.J.G.-M. Derks
Publikováno v:
Steroids, 31(1), 9-22. ELSEVIER SCIENCE INC
This report describes the synthesis of 3alpha,6beta,11beta,17alpha,21-pentahydroxy-5beta-pregnane-20-one, 3alpha,6beta,11beta,17alpha,21-pentahydroxy-5beta-pregnane-20-one, 3alpha,6alpha,11beta,17alpha,21-pentahydroxy-5alpha-pregnane-20-one, 3alpha,6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83fbbcb2195882bc44049dfc3544759
https://research.rug.nl/en/publications/1eaaacf2-fa28-460b-a811-d2bf6b586202
https://research.rug.nl/en/publications/1eaaacf2-fa28-460b-a811-d2bf6b586202
Publikováno v:
Clinica chimica acta, 120(3), 341-353. ELSEVIER SCIENCE BV
The urine of a 6-day-old prematurely born female infant (birth weight 1060 g) suspected of having a 21-OH-deficiency showed no steroid abnormalities on capillary GLC analysis. Using GC-MS tetrahydrocortisone (THE) and also 3 alpha, 17 alpha-dihydroxy
Publikováno v:
Steroids. 44(4)
The preparation of [1,2,3,4-13C] testosterone and of [1,2,3,4-13C] estradiol by total synthesis is described. The 13C labels are introduced by alkylating intermediate 1 with [1,2,3,4-13C]l-iodo-3,3-ethylenedioxybutane ( 2 ) to obtain intermediate 10