Výsledky vyhledávání - "Nick L. Stemm"

Autor: Russell H. Robins, John W. Skoug, Nick L. Stemm

Publikováno v: Pharmaceutical Research. 12:738-745

A gradient high performance liquid chromatographic method was developed to determine degradation products of adinazolam mesylate in a sustained release tablet formulation. Sample preparations were chromatographed on a YMC-Basic column using a formate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88b10caa4c6ed22aaa672f65423dd060
https://doi.org/10.1023/a:1016219927912

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Qualitative evaluation of the mechanism of release of matrix sustained release dosage forms by measurement of polymer release

Autor: John W. Skoug, Cynthia N. Vigneron, Martin V. Mikelsons, Nick L. Stemm

Publikováno v: Journal of Controlled Release. 27:227-245

A method based on size exclusion chromatography and differential viscometric detection was developed for the measurement of polymer concentration in dissolution samples. The method was developed to evaluate the drug release mechanism of matrix sustai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a2ee58459220e8f0c6160f938e77440
https://doi.org/10.1016/0168-3659(93)90154-w

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Swelling of hydroxypropyl methylcellulose matrix tablets. 2. Mechanistic study of the influence of formulation variables on matrix performance and drug release

Autor: Ping Gao, Kuo-Chun Sung, T. Robert Ju, Phillip R. Nixon, Nick L. Stemm, John W. Skoug

Publikováno v: Journal of pharmaceutical sciences. 85(7)

We characterized the effect of hydroxypropyl methylcellulose (HPMC)/lactose ratio and HPMC viscosity grade (molecular weight) on solute release and swelling of matrix tablets. We used a semiquantitative optical imaging method to monitor the swelling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc460cd6bd2a9d09b37b30c2a83cdf7c
https://pubmed.ncbi.nlm.nih.gov/8818998

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Determination of the antileukemia agents cytarabine and azacitidine and their respective degradation products by high-performance liquid chromatography

Autor: Nick L. Stemm, Larry D. Kissinger

Publikováno v: Journal of chromatography. 353

A reversed-phase high-performance liquid chromatography (HPLC) system was developed for the determination of the antineoplastic agents cytarabine and azacitidine. Separations were performed on an octadecylsilane column with a mobile phase of methanol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9e33f897ff2be7e3a9b4e509e7c802
https://pubmed.ncbi.nlm.nih.gov/2422189

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