Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nick J. Gonchoroff"'
Autor:
Andras Perl, Nick J. Gonchoroff, Maureen Barcza, Katalin Banki, Wendy Amidon, Kazim R. Chohan, Karina L. Conkrite, Susan S. Suarez, Frank A. Middleton, Cynthia R. Shirley, Sanjay K. Banerjee, Yueming Qian
Publikováno v:
Proceedings of the National Academy of Sciences. 103:14813-14818
Fertility of spermatozoa depends on maintenance of the mitochondrial transmembrane potential (Δψm), which is generated by the electron-transport chain and regulated by an oxidation–reduction equilibrium of reactive oxygen intermediates, pyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1667f70db2b325cdf561a335722ef1
https://doi.org/10.1073/pnas.0602678103
https://doi.org/10.1073/pnas.0602678103
Autor:
Rudolf Pullmann, Nick J. Gonchoroff, Paul E. Phillips, Brian Niland, Andras Perl, Péter Gergely
Publikováno v:
The Journal of Immunology. 169:1092-1101
Abnormal death signaling in lymphocytes of systemic lupus erythematosus (SLE) patients has been associated with elevation of the mitochondrial transmembrane potential (Δψm) and increased production of reactive oxygen intermediates (ROI). The result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405369edc2f41510f85145ea9071443e
https://doi.org/10.4049/jimmunol.169.2.1092
https://doi.org/10.4049/jimmunol.169.2.1092
Publikováno v:
Cytometry. 46:28-32
The myelodysplastic syndromes (MDS) are clonal hematologic malignancies characterized by pancytopenia, dysplastic hematopoiesis, and a propensity to leukemic transformation. Increased apoptosis has been noted in MDS as a possible explanation for inef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51796a445d16b03749b23565d159b5e
https://doi.org/10.1002/1097-0320(20010215)46:1<28::aid-cyto1034>3.0.co
https://doi.org/10.1002/1097-0320(20010215)46:1<28::aid-cyto1034>3.0.co
Publikováno v:
American Journal of Obstetrics and Gynecology. 183:462-468
Objective: This study was undertaken to determine the fetal E/e or e/e Rh genotype prenatally from peripheral maternal blood by examining sorted fetal cells from alloimmunized and nonalloimmunized pregnancies. Study Design: Eighteen maternal peripher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d833e2768ce2ad43cfab7dd6e08b5ab9
https://doi.org/10.1067/mob.2000.106005
https://doi.org/10.1067/mob.2000.106005
Publikováno v:
Journal of Biological Chemistry. 273:11944-11953
Dysregulated apoptosis may underlie the etiology of T cell depletion by human immunodeficiency virus type 1 (HIV-1). We show that HIV-induced apoptosis is preceded by an exponential increase in reactive oxygen intermediates (ROIs) produced in mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1857f6eb65a92a0443805cbfdc57eb32
https://doi.org/10.1074/jbc.273.19.11944
https://doi.org/10.1074/jbc.273.19.11944
Publikováno v:
Obstetrics & Gynecology. 91:506-510
Objective: To determine the fetal Rhc genotype by using the polymerase chain reaction (PCR) amplification procedure and maternal blood at the different steps of the fetal cell enrichment process. Methods: Maternal peripheral venous blood samples were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b1c7920944fd8ec609334b1fa4e023
https://doi.org/10.1097/00006250-199804000-00005
https://doi.org/10.1097/00006250-199804000-00005
Publikováno v:
Cytometry. 26:253-259
Multi-variable flow cytometry studies were done on paraffin-embedded surgical specimens from 97 patients with bronchiolalveolar carcinoma (BAC) and on 10 normal lung tissue specimens to assess the value of nuclear protein content besides DNA ploidy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fbe55316277f05c9ae276ef2e5ca01a
https://doi.org/10.1002/(sici)1097-0320(19961215)26:4<253::aid-cyto3>3.0.co
https://doi.org/10.1002/(sici)1097-0320(19961215)26:4<253::aid-cyto3>3.0.co
Glutathione Levels and Sensitivity to Apoptosis Are Regulated by Changes in Transaldolase Expression
Publikováno v:
Journal of Biological Chemistry. 271:32994-33001
Transaldolase (TAL) is a key enzyme of the reversible nonoxidative branch of the pentose phosphate pathway (PPP) that is responsible for the generation of NADPH to maintain glutathione at a reduced state (GSH) and, thus, to protect cellular integrity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c755f286fbceaa64929fb7ff871af6
https://doi.org/10.1074/jbc.271.51.32994
https://doi.org/10.1074/jbc.271.51.32994
Autor:
James E. Krook, James A. Mailliard, R J Fitzgibbons, Nick J. Gonchoroff, Michael J. O'Connell, James B. Gerstner, Harry S. Wieand, John H. Donohue, Martin Wiesenfeld, R Pazdur
Publikováno v:
Journal of Clinical Oncology. 13:2324-2329
PURPOSE The primary goal of this study was to assess the effectiveness of interferon gamma (IFN-gamma) to prevent tumor relapse following potentially curative surgery in patients with high-risk colon cancer. A secondary goal was to determine the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de48ef51f325f64814fa34b078b4f7a
https://doi.org/10.1200/jco.1995.13.9.2324
https://doi.org/10.1200/jco.1995.13.9.2324
Autor:
Daniel J. Schaid, James N. Ingle, Steven Cha, Lester E. Wold, Nick J. Gonchoroff, Roxanne L. Tabery, Clive S. Grant, Jerry A. Katzmann, Thomas E. Witzig
Publikováno v:
Cancer. 74:1752-1761
Background. Previous cell kinetic studies have shown that the percentage of cells in S-phase (%S) of the tumor may be an important prognostic factor for relapsefree survival (RFS) and overall survival (OS) in patients with resected lymph node negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62154c98c0c3b6ad00b664fb882b0e1d
https://doi.org/10.1002/1097-0142(19940915)74:6<1752::aid-cncr2820740618>3.0.co
https://doi.org/10.1002/1097-0142(19940915)74:6<1752::aid-cncr2820740618>3.0.co