Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nick Connis"'
Autor:
Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, Janet Wiegand, Peiyi Zhang, Xuan Zhang, Vivekananda Budamagunta, Nan Hua, Yang Yang, Umasankar De, Lingtao Jin, Weizhou Zhang, Guangrong Zheng, Robert Hromas, Christine Hann, Maria Zajac-Kaye, Frederic J. Kaye, Daohong Zhou
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Small-cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. The dismal prognosis in SCLC is in part associated with an upregulation of BCL-2 family anti-apoptotic proteins, including BCL-XL and MCL-1. Unfortun
Externí odkaz:
https://doaj.org/article/35172677c9ab498385ddea2d7bbcff21
Autor:
I-Mei Siu, Jacob Ruzevick, Qi Zhao, Nick Connis, Yuchen Jiao, Chetan Bettegowda, Xuewei Xia, Peter C Burger, Christine L Hann, Gary L Gallia
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78895 (2013)
Chordomas are rare primary bone tumors that occur along the neuraxis. Primary treatment is surgery, often followed by radiotherapy. Treatment options for patients with recurrence are limited and, notably, there are no FDA approved therapeutic agents.
Externí odkaz:
https://doaj.org/article/6730dfb885de47f5b56a2e97daee58b1
Autor:
Xing Wang, Natasha Raman, Ghali Lemtiri-Chlieh, Jinhee Chang, Shreya Jagtap, Dipanwita Dutta Chowdhury, Matthew Ballew, Francesca Anna Carrieri, Triet Nguyen, Katriana Nugent, Travis Peck, Michelle S. Levine, Aaron Chan, Christine Lam, Reem Malek, Tung Hoang, Ryan Phillips, ZhuoAn Cheng, Kekoa Taparra, Nick Connis, Christine L. Hann, Andrew Holland, Phuoc T. Tran, Audrey Lafargue, Hailun Wang
Publikováno v:
Molecular Cancer Therapeutics. 22:519-528
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Autor:
Hailun Wang, Audrey Lafargue, Phuoc T. Tran, Andrew Holland, Christine L. Hann, Nick Connis, Kekoa Taparra, ZhuoAn Cheng, Ryan Phillips, Tung Hoang, Reem Malek, Christine Lam, Aaron Chan, Michelle S. Levine, Travis Peck, Katriana Nugent, Triet Nguyen, Francesca Anna Carrieri, Matthew Ballew, Dipanwita Dutta Chowdhury, Shreya Jagtap, Jinhee Chang, Ghali Lemtiri-Chlieh, Natasha Raman, Xing Wang
Figure S1 shows basal centrosome amplification in cell lines. Figure S2 shows the effect of GF on cell viability. Figure S3 shows HSET expression in cell lines. Figure S4 shows the effect of GF on clonogenic potential after RT. Figure S5 shows the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c532a3a2eded80823b7fec1b40a3091
https://doi.org/10.1158/1535-7163.22552221.v1
https://doi.org/10.1158/1535-7163.22552221.v1
Autor:
Hailun Wang, Audrey Lafargue, Phuoc T. Tran, Andrew Holland, Christine L. Hann, Nick Connis, Kekoa Taparra, ZhuoAn Cheng, Ryan Phillips, Tung Hoang, Reem Malek, Christine Lam, Aaron Chan, Michelle S. Levine, Travis Peck, Katriana Nugent, Triet Nguyen, Francesca Anna Carrieri, Matthew Ballew, Dipanwita Dutta Chowdhury, Shreya Jagtap, Jinhee Chang, Ghali Lemtiri-Chlieh, Natasha Raman, Xing Wang
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66f7a770018e1fbf7d210f058e865a5
https://doi.org/10.1158/1535-7163.c.6534769.v2
https://doi.org/10.1158/1535-7163.c.6534769.v2
Autor:
Christine L. Hann, Jordan J. Green, Charles M. Rudin, Nick Connis, Ron B. Shmueli, Chandrashekhar D. Kamat
Small cell lung cancer (SCLC) is an aggressive disease with one of the highest case-fatality rates among cancer. The recommended therapy for SCLCs has not changed significantly over the past 30 years; new therapeutic approaches are a critical need. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3411e2c9d6b112940d9f761d01b0e1
https://doi.org/10.1158/1535-7163.c.6536083
https://doi.org/10.1158/1535-7163.c.6536083
Autor:
Christine L. Hann, Jordan J. Green, Charles M. Rudin, Nick Connis, Ron B. Shmueli, Chandrashekhar D. Kamat
PDF file - 86 KB, High-throughput screen of a library of PBAE polymers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0967b589d9f4d3ad41428a4fd711bf0a
https://doi.org/10.1158/1535-7163.22499170
https://doi.org/10.1158/1535-7163.22499170
Autor:
Caren L. Freel Meyers, Christine L. Hann, Michelle A. Rudek, Ashani T. Weeraratna, Ming Zhao, Nick Connis, Chandrashekhar Kamat, Marie R. Webster
PDF - 295K, Table S1. In vitro effects of CLO prodrug in NCI-60 cell screen. Table S2. In vitro effects of the CLO prodrug on SK-Mel-5 and UACC-62 melanoma cells. Figure S1. Bisphosphonamidate prodrugs are cell permeable and undergo intracellular act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966f3076782d9bb7bc676458096d5b4c
https://doi.org/10.1158/1535-7163.22499718.v1
https://doi.org/10.1158/1535-7163.22499718.v1
Autor:
Christine L. Hann, Jordan J. Green, Charles M. Rudin, Nick Connis, Ron B. Shmueli, Chandrashekhar D. Kamat
PDF file - 167 KB, The transfection efficiency of 456 polymers is limited by events downstream of binding and uptake.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4035e34c118143e29991a07b1578ba
https://doi.org/10.1158/1535-7163.22499164
https://doi.org/10.1158/1535-7163.22499164