Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nick C. Matthews"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
As the use of hematopoietic stem cell transplantation (HSCT) has become a more widespread and effective treatment for hematological malignant and non-malignant conditions, the need to minimize the harmful effects of graft- vs.-host disease (GvHD) has
Externí odkaz:
https://doaj.org/article/9d15e559695c4625ab1d2283f8c752fb
Publikováno v:
Clinical and Experimental Immunology. 205:257-273
Summary Chronic graft-versus-host disease (cGVHD) is a frequent complication of allogeneic haematopoietic stem cell transplantation. Low density neutrophils (LDNs) in autoimmunity, which shares disease features with cGVHD, are proinflammatory, wherea
Publikováno v:
Clin Exp Immunol
Chronic graft‐versus‐host disease (cGVHD) is a frequent complication of allogeneic haematopoietic stem cell transplantation. Low density neutrophils (LDNs) in autoimmunity, which shares disease features with cGVHD, are proinflammatory, whereas th
Autor:
Elizabeth H. Mann, Catherine M. Hawrylowicz, Tak H. Lee, Paul E Pfeffer, Nick C Matthews, Christopher Corrigan, Frank J. Kelly
Exposure to urban particulate matter (UPM) exacerbates asthmatic lung inflammation. Lung dendritic cells (DCs) are critical for stimulating T cell immunity and in maintaining airway tolerance, but they also react to airway UPM. The adjuvant role of U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f71067ca7cbe44bafdf755984899a1
https://ora.ox.ac.uk/objects/uuid:03bfcfc2-2729-4559-8ef1-f3e1902c0d70
https://ora.ox.ac.uk/objects/uuid:03bfcfc2-2729-4559-8ef1-f3e1902c0d70
Autor:
Ian Mudway, Elizabeth H. Mann, Elfy B Chevretton, Tzer-Ren Ho, Catherine M. Hawrylowicz, Paul E Pfeffer, Nick C Matthews, Frank J. Kelly
Publikováno v:
Mann, E H, Ho, T-R, Pfeffer, P E, Matthews, N C, Chevretton, E, Mudway, I S, Kelly, F J & Hawrylowicz, C M 2017, ' Vitamin D counteracts an IL-23-dependent IL-17A+IFN-γ+ response driven by urban particulate matter ', American Journal of Respiratory Cell and Molecular Biology, vol. 57, no. 3, pp. 355-366 . https://doi.org/10.1165/rcmb.2016-0409OC
Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL-17A, which UPM is reported to promote. Here, we used a myeloid dend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e3d471e25d01deb6044770ce3f7828
https://doi.org/10.1165/rcmb.2016-0409oc
https://doi.org/10.1165/rcmb.2016-0409oc
Autor:
Elizabeth H, Mann, Tzer-Ren, Ho, Paul E, Pfeffer, Nick C, Matthews, Elfy, Chevretton, Ian, Mudway, Frank J, Kelly, Catherine M, Hawrylowicz
Publikováno v:
American journal of respiratory cell and molecular biology. 57(3)
Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL-17A, which UPM is reported to promote. Here, we used a myeloid dend
Publikováno v:
European Journal of Immunology. 41:1958-1968
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class
Publikováno v:
International Immunology. 19:703-712
The functional capability of human neonatal CD4 T cells to respond to vaccine antigens is frequently described as Th2 biased, but whether this is due to defective T-cell or antigen-presenting cell (APC) function is unclear. In this study, we used pur
Publikováno v:
British Journal of Haematology. 113:925-931
Dendritic cells (DCs) are the most potent antigen-presenting cells described to date. In human peripheral blood, both myeloid and lymphoid subsets of DCs have been identified. In contrast, cord blood (CB) DCs have recently been described as being exc
Autor:
Tzer-Ren Ho, Nick C Matthews, Paul E Pfeffer, Catherine M. Hawrylowicz, Elizabeth H. Mann, Frank J. Kelly
Publikováno v:
Thorax. 69:A27-A28
Background High levels of ambient urban particulate matter (UPM), a component of air pollution, are associated with respiratory tract infections and exacerbations of airways diseases. Dendritic cells (DCs) exposed to inhaled UPM orchestrate the resul