Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nick Boice"'
Autor:
Mateusz Opyrchal, Kian-Huat Lim, Jace Webster, Saiama N. Waqar, Albert C. Lockhart, Ningying Wu, Christopher G. Maher, Nick Boice, Joel Picus, Andrea Wang-Gillam, Benjamin R. Tan, Feng Gao, Maria Q. Baggstrom, Abhi Acharya, Daniel Morgensztern, Ramaswamy Govindan
Publikováno v:
European Journal of Cancer. 154:102-110
Aim Aurora kinase A (AURKA) is a pleiotropic serine/threonine kinase that orchestrates mitotic progression. Paclitaxel stabilises microtubules and disrupts mitotic spindle assembly. The combination of AURKA inhibitor (alisertib) plus paclitaxel may b
Autor:
Andrea S. Teague, Jesse Huffman, Benjamin R. Tan, A. Craig Lockhart, Patrick M. Grierson, Kian-Huat Lim, Nick Boice, Lingling Du, Manik Amin, Jingxia Liu, Andrea Wang-Gillam, Rama Suresh, Katrina S. Pedersen
Publikováno v:
Journal of Gastrointestinal Oncology. 11:61-67
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with limited therapeutic options. We evaluated the safety and efficacy of the aminopeptidase inhibitor tosedostat with capecitabine in advanced PDAC. Methods: We conducte