Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nick A, Kuburich"'
Autor:
Nick A. Kuburich, Petra den Hollander, Maria Castaneda, Mika Pietilä, Ximing Tang, Harsh Batra, Francisco Martínez-Peña, Tanvi H. Visal, Tieling Zhou, Breanna R. Demestichas, Ritesh V. Dontula, Jojo Y. Liu, Joanna Joyce Maddela, Reethi S. Padmanabhan, Lan Thi Hanh Phi, Matthew J. Rosolen, Thiru Sabapathy, Dhiraj Kumar, Filippo G. Giancotti, Luke L. Lairson, Maria Gabriela Raso, Rama Soundararajan, Sendurai A. Mani
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113470- (2023)
Summary: Epithelial-mesenchymal transition (EMT) empowers epithelial cells with mesenchymal and stem-like attributes, facilitating metastasis, a leading cause of cancer-related mortality. Hybrid epithelial-mesenchymal (E/M) cells, retaining both epit
Externí odkaz:
https://doaj.org/article/253d5b2d577048579918e7d5d14d75ec
Publikováno v:
Seminars in Cancer Biology. 87:17-31
Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from metastatic disease. Combating cancer metastasis and post-therapeutic recurrence successfully requires understanding each step of metastatic progression. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9040e633a3593c110641145095a87308
https://doi.org/10.1016/j.semcancer.2022.10.006
https://doi.org/10.1016/j.semcancer.2022.10.006
Publikováno v:
Seminars in Cancer Biology. 86:816-826
The cytoskeleton plays an integral role in maintaining the integrity of epithelial cells. Epithelial cells primarily employ cytokeratin in their cytoskeleton, whereas mesenchymal cells use vimentin. During the epithelial-mesenchymal transition (EMT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abacd70cfe86327bba09a90f0a2e361
https://doi.org/10.1016/j.semcancer.2021.12.006
https://doi.org/10.1016/j.semcancer.2021.12.006
EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures
Autor:
Nick A. Kuburich, Suhas Vasaikar, Rama Soundararajan, Sridevi Addanki, Sriya Kudaravalli, Abhijeet Deshmukh, Jeffrey T. Chang, Robiya Joseph, Sendurai A. Mani, Petra den Hollander
Publikováno v:
British Journal of Cancer
Background The epithelial-mesenchymal transition (EMT) enables dissociation of tumour cells from the primary tumour mass, invasion through the extracellular matrix, intravasation into blood vessels and colonisation of distant organs. Cells that rever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f49b1c349d23654a0128ba427e6950
http://europepmc.org/articles/PMC7782839
http://europepmc.org/articles/PMC7782839
Autor:
Abhijeet P, Deshmukh, Petra, den Hollander, Nick A, Kuburich, Suhas, Vasaikar, Robiya, Joseph, Sendurai A, Mani
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. CSCs possess tumor initiation potential as well as the ability to resist toxic compounds and chemotherapeutic agents through the upregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c23aefee026ab15e90f83b5116814be
https://pubmed.ncbi.nlm.nih.gov/35507184
https://pubmed.ncbi.nlm.nih.gov/35507184
Autor:
Nick A, Kuburich, Petra, den Hollander, Abhijeet P, Deshmukh, Suhas, Vasaikar, Robiya, Joseph, Max S, Wicha, Sendurai A, Mani
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. In this chapter, we provide a detailed method for the quantification of CSCs in vitro through mammosphere formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c3441456ba1f72507a2515f936ba403
https://pubmed.ncbi.nlm.nih.gov/35507185
https://pubmed.ncbi.nlm.nih.gov/35507185
Autor:
Petra, den Hollander, Robiya, Joseph, Suhas, Vasaikar, Nick A, Kuburich, Abhijeet P, Deshmukh, Sendurai A, Mani
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. Calculating the frequency of tumor-initiating cells is important in the assessment of the number of CSCs present in a cell population. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc4abb560f21deb9f97568d07896ebe5
https://pubmed.ncbi.nlm.nih.gov/35507188
https://pubmed.ncbi.nlm.nih.gov/35507188
Publikováno v:
Microbiology. 166:129-140
Mitogen-activated protein kinase (MAPK) regulation of cAMP-specific phosphodiesterase function has been demonstrated in mammalian cells and suspected to occur in other eukaryotes. Epistasis analysis in the soil amoeba Dictyostelium discoideum suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e4f0f19656d038f47637d61d098bdda
https://doi.org/10.1099/mic.0.000868
https://doi.org/10.1099/mic.0.000868
Autor:
Nick A. Kuburich, Petra den Hollander, Abhijeet P. Deshmukh, Suhas Vasaikar, Robiya Joseph, Max S. Wicha, Sendurai A. Mani
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc0c3637cdf498ea863e482bf7b7c1e
https://doi.org/10.1007/978-1-0716-1979-7_35
https://doi.org/10.1007/978-1-0716-1979-7_35
Autor:
Abhijeet P. Deshmukh, Petra den Hollander, Nick A. Kuburich, Suhas Vasaikar, Robiya Joseph, Sendurai A. Mani
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::758def9083fd63efd315857e9424ee26
https://doi.org/10.1007/978-1-0716-1979-7_34
https://doi.org/10.1007/978-1-0716-1979-7_34