Shadows of Reality: A Catalogue of W.G. Sebald's Photographic Materials: Edited by Clive Scott and Nick Warr, Boiler House Press, 2023, 440 pp., ISBN 9781911343660.

Autor: Blaufuks, Daniel

Publikováno v: Photography & Culture; Mar2024, Vol. 17 Issue 1, p117-120, 4p

Gadd45g is required for timely Sry expression independently of RSPO1 activity

Autor: Nick Warr, Pam Siggers, Joel May, Nicolas Chalon, Madeleine Pope, Sara Wells, Marie-Christine Chaboissier, Andy Greenfield

Publikováno v: Reproduction
Reproduction, 2022, 163, pp.333-340. ⟨10.1530/REP-21-0443⟩

Sex determination in mammals is controlled by the dominance of either pro-testis (SRY-SOX9-FGF9) or pro-ovary (RSPO1-WNT4-FOXL2) genetic pathways during early gonad development in XY and XX embryos, respectively. We have previously shown that early,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d49f94595e554086181111647750e3
https://hal.science/hal-03650971

A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.

Autor: Pam Siggers, Gwenn-Aël Carré, Debora Bogani, Nick Warr, Sara Wells, Helen Hilton, Chris Esapa, Mohammad K Hajihosseini, Andy Greenfield

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e100447 (2014)

The secreted molecule fibroblast growth factor 9 (FGF9) plays a critical role in testis determination in the mouse. In embryonic gonadal somatic cells it is required for maintenance of SOX9 expression, a key determinant of Sertoli cell fate. Conditio

Externí odkaz: https://doaj.org/article/b46f7a2ea5db4085af07bdc27de8d884

Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome

Autor: Tiphanie Merel, Matthieu Peycelon, Serge Nef, Daisylyn Senna Tan, Evgenia Globa, Rita Bertalan, Inas Mazen, John C. Achermann, Andy Greenfield, Romain Le Ru, Jean-Pierre Siffroi, Anne Jorgensen, Ken McElreavey, Ágnes Sallai, Brigitte Mignot, Ralf Jauch, Laetitia Martinerie, Raissa G. G. Kay, Gerard S. Conway, Joelle Bignon-Topalovic, Juliane Léger, Nick Warr, Denis Houzelstein, Federica Buonocore, Anu Bashamboo, Raja Brauner, Caroline Eozenou, Lionel Van Maldergem, Yuliya Shcherbak, Jean-Claude Carel

Publikováno v: Genetics in Medicine
Genetics in Medicine, Nature Publishing Group, 2020, 22 (1), pp.150-159. ⟨10.1038/s41436-019-0606-y⟩
Genetics in Medicine, Nature Publishing Group, In press, ⟨10.1038/s41436-019-0606-y⟩
Genetics in Medicine (2019)
Genetics in Medicine, 2020, 22 (1), pp.150-159. ⟨10.1038/s41436-019-0606-y⟩

International audience; PURPOSE:XY individuals with disorders/differences of sex development (DSD) are characterized by reduced androgenization caused, in some children, by gonadal dysgenesis or testis regression during fetal development. The genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8f7f93f0dd958aeec82a17aa535799
https://hal-pasteur.archives-ouvertes.fr/pasteur-02376177

ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling

Autor: Silvia Corrochano, Abigail Harris, Hans Clevers, Caroline Eozenou, Isabelle Stévant, Joelle Bignon-Topalovic, Nick Warr, Neila Belguith, Sara Wells, Bochra Ben Rhouma, Pam Siggers, Serge Nef, Daniel T. Grimes, Ken McElreavey, Rebecca D. Burdine, Feng Cong, Makoto Suzuki, Andy Greenfield, Danielle Sagar, Anu Bashamboo, Bon-Kyoung Koo, Raja Brauner

Publikováno v: Proceedings of the National Academy of Sciences, Vol. 115, No 21 (2018) pp. 5474-5479
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474-5479. National Academy of Sciences

International audience; Mammalian sex determination is controlled by the antagonistic interactions of two genetic pathways: The SRY-SOX9-FGF9 network promotes testis determination partly by opposing proovarian pathways, while RSPO1/WNT-β-catenin/FOX

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f785b7c346bbb98027161ca7382405e7
https://hdl.handle.net/20.500.11755/a85a814a-a5a7-4064-9ca8-516f15a8bb58