Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nick, Palmer"'
Autor:
Bryton Praslicka, Matthew Johnson, Erik Plugge, Nick Palmer, Donald F. Knight, Adam White, Thomas Simms, Daniel Zamarron, Hamid A. Toliyat
Publikováno v:
IEEE/ASME Transactions on Mechatronics. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f296527c6abc6fdca0b931cc338fd740
https://doi.org/10.1109/tmech.2023.3266111
https://doi.org/10.1109/tmech.2023.3266111
Autor:
Mohaned Egred, Alan Bagnall, Ioakim Spyridopoulos, Ian F. Purcell, Rajiv Das, Nick Palmer, Ever D. Grech, Ajay Jain, Gregg W. Stone, Robin Nijveldt, Thomas McAndrew, Azfar Zaman
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 28, Iss , Pp 100526- (2020)
Background: The aim of this clinical research was to investigate the effects of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size at 5 days after primary percutaneous coronary intervention (pPCI) in patients with ST-se
Externí odkaz:
https://doaj.org/article/c975f23ce7914ee3be9b92d31daaca14
Autor:
Bryton Praslicka, Donald F. Knight, Tazio L. Stefanelli, Nick Palmer, Adam White, Joshua Jones, Hamid A. Toliyat
Publikováno v:
2022 IEEE Energy Conversion Congress and Exposition (ECCE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c1ccc1c81fddea0678a38628aeb615
https://doi.org/10.1109/ecce50734.2022.9947669
https://doi.org/10.1109/ecce50734.2022.9947669
Autor:
Michael Reader, Aurélie Courtin, Steven Howard, Nicola G. Wallis, Jonathan Shannon, Hugh Walton, Christopher William Murray, Joseph E. Coyle, Joanne M. Munck, Alison Jo-Anne Woolford, Torren M. Peakman, David C. Rees, James Edward Harvey Day, Charlotte Mary Griffiths-Jones, Marc O'Reilly, Alpesh Shah, David Norton, Valerio Berdini, Lynsey Fazal, Maria Grazia Carr, Charlotte East, Tom D. Heightman, Nicola E. Wilsher, Ildiko Maria Buck, Luke Bevan, Stuart Thomas Onions, Michael Cooke, Justyna Kucia-Tran, Sandra Muench, Nick Palmer, Sharna J. Rich, Vanessa Martins, David Cousin, Puja Pathuri, John P. Watts
Publikováno v:
Journal of medicinal chemistry. 64(16)
Aberrant activation of the mitogen-activated protein kinase pathway frequently drives tumor growth, and the ERK1/2 kinases are positioned at a key node in this pathway, making them important targets for therapeutic intervention. Recently, a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d0e8543148c5c72af0eca510047c9f
https://pubmed.ncbi.nlm.nih.gov/34387469
https://pubmed.ncbi.nlm.nih.gov/34387469
Autor:
Neil T. Thompson, Charlotte Mary Griffiths-Jones, John Lyons, Vanessa Martins, Nicola E. Wilsher, Tom D. Heightman, Harpreet K Saini, Juan Castro, Stuart Thomas Onions, David Cousin, Nicola G. Wallis, Valerio Berdini, Nick Palmer, Puja Pathuri, Caroline Richardson, Christopher William Murray, Charlotte East, John P. Watts, Marc O'Reilly, Sharna J. Rich, Hugh Walton, James Edward Harvey Day, Aurélie Courtin, Brent Graham, David C. Rees, Hannah Braithwaite, Michael Cooke, Ildiko Maria Buck, Michael Reader, Sandra Muench, Megan Cassidy, Jonathan Shannon, Joanne M. Munck, Alison Jo-Anne Woolford, David Norton, Lynsey Fazal
Publikováno v:
Journal of Medicinal Chemistry. 61:4978-4992
Aberrant activation of the MAPK pathway drives cell proliferation in multiple cancers. Inhibitors of BRAF and MEK kinases are approved for the treatment of BRAF mutant melanoma, but resistance frequently emerges, often mediated by increased signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64bcd2385197c9e1b7f9532e4d26523
https://doi.org/10.1021/acs.jmedchem.8b00421
https://doi.org/10.1021/acs.jmedchem.8b00421
Publikováno v:
Interventional Cardiology.
Aim Revascularisation of CTOs is a technically challenging procedure and complex cases often require dual access. Advancements in techniques have made bi-radial access more feasible. However, the limited evidence suggests that in patients with comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d641e9ad2d236975cf42388a0dec5ff9
https://doi.org/10.1136/heartjnl-2019-bcs.56
https://doi.org/10.1136/heartjnl-2019-bcs.56
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 10, Pp 1686-1687 (2009)
Externí odkaz:
https://doaj.org/article/3f500ce38dfb43e3a1a356d91b8befef
Publikováno v:
Organic & Biomolecular Chemistry. 14:1599-1610
This study describes general synthesis aspects of fragments for FBDD, as illustrated by the dihydroisoquinolones 1-3. Previous Rh(III) methodology is extended to incorporate amines, heteroatoms (N and S), and substituents (halogen, ester) as potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70915c38a9597db119dd6f8db55857e8
https://doi.org/10.1039/c5ob02461g
https://doi.org/10.1039/c5ob02461g
Autor:
Christopher Charles Frederick Hamlett, Shimamura Tadashi, Steve Hiscock, Keisha Hearn, Juan Castro, T.G. Davies, Philip J. Day, James Edward Harvey Day, Yasuo Kodama, Kenichi Matsuo, Nicola G. Wallis, Amanda J. Price, Rhian S. Holvey, Valerio Berdini, Nick Palmer, Christopher N. Johnson, Gianni Chessari, Jeffrey D. St. Denis, Yoko Nakatsuru, Glyn Williams, Satoshi Fukaya, Satoru Ito
Publikováno v:
Cancer Research. 80:1039-1039
The ubiquitously expressed protein tyrosine phosphatase SHP2 is required for signalling downstream of receptor tyrosine kinases (RTKs) and plays a role in regulating many cellular processes. Recent advances have shown that genetic knockdown and pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05e51817378141de98efd04bfce5ba9
https://doi.org/10.1158/1538-7445.am2020-1039
https://doi.org/10.1158/1538-7445.am2020-1039
Autor:
Pradeep Magapu, Nick Palmer
Publikováno v:
Cases in Structural Cardiac Intervention ISBN: 9781447149804
Patent foreman ovale (PFO) is common in the adult population with a prevalence of 25 %. The foreman ovale is an anatomical structure that develops during foetal growth which allows passage of blood from the right into the left atrium. In utero, it al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18f356a7f302be4218e2c5daa9e1fe2
https://doi.org/10.1007/978-1-4471-4981-1_6
https://doi.org/10.1007/978-1-4471-4981-1_6
